- AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster
[作者:Kametaka, S; Kametaka, A; Yonekura, S; Haruta, M; Takenoshita, S; Goto, S; Waguri, S,期刊:Journal of cell science, 页码:634-648 , 文章类型: Article,,卷期:2012年125-3]
- Clathrin adaptor protein complex-1 (AP-1) and its accessory proteins play a role in the sorting of integral membrane proteins at the trans-Golgi network and endosomes. Their physiological functions in complex organisms, ...
- Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution
[作者:Loschberger, A; van de Linde, S; Dabauvalle, MC; Rieger, B; Heilemann, M; Krohne, G; Sauer, M,期刊:Journal of cell science, 页码:570-575 , 文章类型: Article,,卷期:2012年125-3]
- One of the most complex molecular machines of cells is the nuclear pore complex (NPC), which controls all trafficking of molecules in and out of the nucleus. Because of their importance for cellular processes such as gen...
- CASK (LIN2) interacts with Cx43 in wounded skin and their coexpression affects cell migration
[作者:Marquez-Rosado, L; Singh, D; Rincon-Arano, H; Solan, JL; Lampe, PD,期刊:Journal of cell science, 页码:695-702 , 文章类型: Article,,卷期:2012年125-3]
- Vertebrate gap junctions are composed of proteins from the connexin family. Co-immunoprecipitation, in vitro binding and far western experiments demonstrate that mammalian CASK (also known as LIN2) directly interacts wit...
- Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells
[作者:Smoligovets, AA; Smith, AW; Wu, HJ; Petit, RS; Groves, JT,期刊:Journal of cell science, 页码:735-742 , 文章类型: Article,,卷期:2012年125-3]
- T cell triggering through T-cell antigen receptors (TCRs) results in spatial assembly of the receptors on multiple length scales. This assembly is mediated by the T cell actin cytoskeleton, which reorganizes in response ...
- Differential regulation of myosin X movements by its cargos, DCC and neogenin
[作者:Liu, Y; Peng, Y; Dai, PG; Du, QS; Mei, L; Xiong, WC,期刊:Journal of cell science, 页码:751-762 , 文章类型: Article,,卷期:2012年125-3]
- Myosin X (Myo X), also known as MYO10, is an unconventional actin-based motor protein that plays an important role in filopodium formation. Its intra-filopodia movement, an event tightly associated with the function of M...
- N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors
[作者:Gligorijevic, B; Wyckoff, J; Yamaguchi, H; Wang, YR; Roussos, ET; Condeelis, J,期刊:Journal of cell science, 页码:724-734 , 文章类型: Article,,卷期:2012年125-3]
- Invadopodia are proteolytic membrane protrusions formed by highly invasive cancer cells, commonly observed on substrate(s) mimicking extracellular matrix. Although invadopodia are proposed to have roles in cancer invasio...
- The transient appearance of zipper-like actin superstructures during the fusion of osteoclasts
[作者:Takito, J; Nakamura, M; Yoda, M; Tohmonda, T; Uchikawa, S; Horiuchi, K; Toyama, Y; Chiba, K,期刊:Journal of cell science, 页码:662-672 , 文章类型: Article,,卷期:2012年125-3]
- Multinucleated osteoclasts are responsible for bone resorption. Hypermultinucleated osteoclasts are often observed in some bone-related diseases such as Paget's disease and cherubism. The cellular mechanics controlling t...
- Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division
[作者:Itoyama, A; Honsho, M; Abe, Y; Moser, A; Yoshida, Y; Fujiki, Y,期刊:Journal of cell science, 页码:589-602 , 文章类型: Article,,卷期:2012年125-3]
- Peroxisome division is regulated by several factors, termed fission factors, as well as the conditions of the cellular environment. Over the past decade, the idea of metabolic control of peroxisomal morphogenesis has bee...
- Down's-syndrome-related kinase Dyrk1A modulates the p120-catenin-Kaiso trajectory of the Wnt signaling pathway
[作者:Hong, JY; Park, JI; Lee, M; Munoz, WA; Miller, RK; Ji, H; Gu, DM; Sokol, SY; McCrea, PD,期刊:Journal of cell science, 页码:561-569 , 文章类型: Article,,卷期:2012年125-3]
- The Wnt pathways contribute to many processes in cancer and development, with beta-catenin being a key canonical component. p120-catenin, which is structurally similar to beta-catenin, regulates the expression of certain...
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