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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   What precedes the initial tyrosine phosphorylation of the high affinity IgE receptor in antigen-activated mast cell? [作者：Bugajev, V; Bambouskova, M; Draberova, L; Draber, P,期刊：FEBS Letters, 页码：4949-4955 , 文章类型： Review，,卷期：2010年584-24] An interaction of multivalent antigen with its IgE bound to the high-affinity IgE receptor (Fc epsilon RI) on the surface of mast cells or basophils initiates a series of signaling events leading to degranulation and rel... Signalling by immunoreceptors Preface [作者：Pecht, I,期刊：FEBS Letters, 页码：4813-4813 , 文章类型： Editorial Material，,卷期：2010年584-24] Computational analysis of T cell receptor signaling and ligand discrimination - Past, present, and future [作者：Germain, RN,期刊：FEBS Letters, 页码：4814-4822 , 文章类型： Review，,卷期：2010年584-24] Signaling through the T cell receptor for antigen (TCR) has been studied for years by conventional biochemical means. More recently, attempts have been made to develop computational models of signaling through this recep... Signaling microdomains in T cells [作者：Choudhuri, K; Dustin, ML,期刊：FEBS Letters, 页码：4823-4831 , 文章类型： Review，,卷期：2010年584-24] Sub-micron scale signaling domains induced in the plasma membrane of cells are thought to play important roles in signal transduction. In T cells, agonist MHC-peptide complexes induce small diffraction-limited domains en... Pre-clustered TCR complexes [作者：Molnar, E; Deswal, S; Schamel, WWA,期刊：FEBS Letters, 页码：4832-4837 , 文章类型： Review，,卷期：2010年584-24] The T-cell antigen receptor (TCR) is a multisubunit transmembrane complex that mediates the antigen-specific activation of T cells. Using a variety of techniques, several research groups have shown that TCRs are at least... CD46 signaling in T cells: Linking pathogens with polarity [作者：Hawkins, ED; Oliaro, J,期刊：FEBS Letters, 页码：4838-4844 , 文章类型： Review，,卷期：2010年584-24] CD46 is a cell surface protein that regulates complement activity and is utilized as a receptor by numerous viral and bacterial pathogens that infect humans. CD46 is not just an entry site for pathogens, but can affect v... Cytoskeletal cross-talk in the control of T cell antigen receptor signaling [作者：Lasserre, R; Alcover, A,期刊：FEBS Letters, 页码：4845-4850 , 文章类型： Review，,卷期：2010年584-24] T cell antigen receptor signaling is triggered and controlled in specialized cellular interfaces formed between T cells and antigen-presenting cells named immunological synapses. Both microtubules and actin cytoskeleton ... The space and time frames of T cell activation at the immunological synapse [作者：Valitutti, S; Coombs, D; Dupre, L,期刊：FEBS Letters, 页码：4851-4857 , 文章类型： Review，,卷期：2010年584-24] The selective recognition of antigenic peptides by T cells requires the spatio/temporal integration of a panoply of molecular triggers. The space frame of T cell antigen receptors (TCR) interaction with peptide/MHC compl... Multiple pathways leading from the T-cell antigen receptor to the actin cytoskeleton network [作者：Reicher, B; Barda-Saad, M,期刊：FEBS Letters, 页码：4858-4864 , 文章类型： Review，,卷期：2010年584-24] Dynamic rearrangements of the actin cytoskeleton, following T-cell antigen receptor (TCR) engagement, provide the structural matrix and flexibility to enable intracellular signal transduction, cellular and subcellular re... Dynamic regulation of T cell activation and co-stimulation through TCR-microclusters [作者：Saito, T; Yokosuka, T; Hashimoto-Tane, A,期刊：FEBS Letters, 页码：4865-4871 , 文章类型： Review，,卷期：2010年584-24] TCR-microclusters (MC) are generated upon TCR stimulation prior to the immune synapse formation independently of lipid rafts. TCR-MCs contain receptors, kinases and adaptors, and function as the signaling unit for T cell... The dissociation activation model of B cell antigen receptor triggering [作者：Yang, JY; Reth, M,期刊：FEBS Letters, 页码：4872-4877 , 文章类型： Review，,卷期：2010年584-24] To detect its cognate antigen, each B lymphocyte contains up to 120 000 B cell antigen receptor (BCR) complexes on its cell surface. How these abundant receptors remain silent on resting B cells and how they can be activ... The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: Potential molecular mechanisms [作者：Waterman, PM; Cambier, JC,期刊：FEBS Letters, 页码：4878-4882 , 文章类型： Review，,卷期：2010年584-24] Immunoreceptor signals must be appropriately transduced and regulated to achieve effective immunity while controlling inflammation and autoimmunity. It is generally held that these processes are mediated by the interplay... Receptors and signaling mechanisms for B-lymphocyte activation, proliferation and differentiation - Insights from both in vivo and in vitro approaches [作者：Maddaly, R; Pai, G; Balaji, S; Sivaramakrishnan, P; Srinivasan, L; Sunder, SS; Paul, SFD,期刊：FEBS Letters, 页码：4883-4894 , 文章类型： Review，,卷期：2010年584-24] During the last three decades, a number of B-lymphocyte specific surface antigens have been defined some of which may also show activation/differentiation specific expression. Here, we review the various signaling events... Paired NK cell receptors controlling NK cytotoxicity [作者：Stanietsky, N; Mandelboim, O,期刊：FEBS Letters, 页码：4895-4900 , 文章类型： Review，,卷期：2010年584-24] Human natural killer (NK) cells possess an arsenal of receptors programmed to regulate the NK cell functions, once encountering a target cell. In general, the activating receptors mediate cytotoxicity when engaged by the... Understanding signal integration through targeted mutations of an adapter protein [作者：Zou, T; May, RM; Koretzky, GA,期刊：FEBS Letters, 页码：4901-4909 , 文章类型： Review，,卷期：2010年584-24] Immunoreceptor engagement leads to the activation of multiple second messenger cascades, and integration of these pathways requires proper function of a number of adapter proteins. Although adapters possess no intrinsic ... Ikaros in immune receptor signaling, lymphocyte differentiation, and function [作者：Merkenschlager, M,期刊：FEBS Letters, 页码：4910-4914 , 文章类型： Review，,卷期：2010年584-24] Ikaros is the founding member of a family of transcription factors. Ikaros proteins are required for the normal development of lymphocytes and other blood cell lineages, and have an important role in haematopoietic malig...