- Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies
[作者:Hassett, DJ; Korfhagen, TR; Irvin, RT; Schurr, MJ; Sauer, K; Lau, GW; Sutton, MD; Yu, HW; Hoiby, N,期刊:Expert Opinion on Therapeutic Targets, 页码:117-130 , 文章类型: Review,,卷期:2010年14-2]
- Importance of the field: CF airway mucus can be infected by opportunistic microorganisms, notably Pseudomonas aeruginosa. Once organisms are established as biofilms, even the most potent antibiotics have little effect on...
- Fractalkine/CX3CR1: why a single chemokine-receptor duo bears a major and unique therapeutic potential
[作者:D'Haese, JG; Demir, IE; Friess, H; Ceyhan, GO,期刊:Expert Opinion on Therapeutic Targets, 页码:207-219 , 文章类型: Review,,卷期:2010年14-2]
- Importance of the field. Fractalkine, also known as CX3CL1, is the unique member of the fourth class of chemokines and mediates both chemotaxis and adhesion of inflammatory cells via its highly selective receptor CX3CR1....
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