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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共14条记录   Actin takes its hat off to dynamin [作者：Roux, A; Plastino, J,期刊：EMBO journal, 页码：3591-3592 , 文章类型： Editorial Material，,卷期：2010年29-21] A major player in membrane traffic, the large GTPase dynamin, is known in the actin dynamics field for its indirect association with the actin cytoskeleton via actin-binding proteins (ABPs) like cortactin. In this issue ... Direct dynamin-actin interactions regulate the actin cytoskeleton [作者：Gu, C; Yaddanapudi, S; Weins, A; Osborn, T; Reiser, J; Pollak, M; Hartwig, J; Sever, S,期刊：EMBO journal, 页码：3593-3606 , 文章类型： Article，,卷期：2010年29-21] The large GTPase dynamin assembles into higher order structures that are thought to promote endocytosis. Dynamin also regulates the actin cytoskeleton through an unknown, GTPase-dependent mechanism. Here, we identify a h... Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders [作者：Fraldi, A; Annunziata, F; Lombardi, A; Kaiser, HJ; Medina, DL; Spampanato, C; Fedele, AO; Polishchuk, R; Sorrentino, NC; Simons, K; Ballabio, A,期刊：EMBO journal, 页码：3607-3620 , 文章类型： Article，,卷期：2010年29-21] The function of lysosomes relies on the ability of the lysosomal membrane to fuse with several target membranes in the cell. It is known that in lysosomal storage disorders (LSDs), lysosomal accumulation of several types... CtsR, the Gram-positive master regulator of protein quality control, feels the heat [作者：Elsholz, AKW; Michalik, S; Zuhlke, D; Hecker, M; Gerth, U,期刊：EMBO journal, 页码：3621-3629 , 文章类型： Article，,卷期：2010年29-21] Protein quality networks are required for the maintenance of proper protein homeostasis and essential for viability and growth of all living organisms. Hence, regulation and coordination of these networks are critical fo... Spatial and temporal organization of the E. coli PTS components [作者：Lopian, L; Elisha, Y; Nussbaum-Shochat, A; Amster-Choder, O,期刊：EMBO journal, 页码：3630-3645 , 文章类型： Article，,卷期：2010年29-21] The phosphotransferase system (PTS) controls preferential use of sugars in bacteria. It comprises of two general proteins, enzyme I (EI) and HPr, and various sugar-specific permeases. Using fluorescence microscopy, we sh... Molecular organization and dynamics of the melatonin MT1 receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling [作者：Maurice, P; Daulat, AM; Turecek, R; Ivankova-Susankova, K; Zamponi, F; Kamal, M; Clement, N; Guillaume, JL; Bettler, B; Gales, C; Delagrange, P; Jockers, R,期刊：EMBO journal, 页码：3646-3659 , 文章类型： Article，,卷期：2010年29-21] Functional asymmetry of G-protein-coupled receptor (GPCR) dimers has been reported for an increasing number of cases, but the molecular architecture of signalling units associated to these dimers remains unclear. Here, w... CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation [作者：Kasper, LH; Lerach, S; Wang, JM; Wu, S; Jeevan, T; Brindle, PK,期刊：EMBO journal, 页码：3660-3672 , 文章类型： Article，,卷期：2010年29-21] It remains uncertain how the DNA sequence of mammalian genes influences the transcriptional response to extracellular signals. Here, we show that the number of CREB-binding sites (CREs) affects whether the related histon... Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion [作者：Kokura, K; Sun, LD; Bedford, MT; Fang, J,期刊：EMBO journal, 页码：3673-3687 , 文章类型： Article，,卷期：2010年29-21] H3K9 methylation has been linked to a variety of biological processes including position-effect variegation, heterochromatin formation and transcriptional regulation. To further understand the function of H3K9 methylatio... Hen1 is required for oocyte development and piRNA stability in zebrafish [作者：Kamminga, LM; Luteijn, MJ; den Broeder, MJ; Redl, S; Kaaij, LJT; Roovers, EF; Ladurner, P; Berezikov, E; Ketting, RF,期刊：EMBO journal, 页码：3688-3700 , 文章类型： Article，,卷期：2010年29-21] Piwi-interacting RNAs (piRNAs) are germ line-specific small RNA molecules that have a function in genome defence and germ cell development. They associate with a specific class of Argonaute proteins, named Piwi, and func... Optimization of speed and accuracy of decoding in translation [作者：Wohlgemuth, I; Pohl, C; Rodnina, MV,期刊：EMBO journal, 页码：3701-3709 , 文章类型： Article，,卷期：2010年29-21] The speed and accuracy of protein synthesis are fundamental parameters for understanding the fitness of living cells, the quality control of translation, and the evolution of ribosomes. In this study, we analyse the spee... Polypyrimidine tract-binding protein stimulates the poliovirus IRES by modulating eIF4G binding [作者：Kafasla, P; Morgner, N; Robinson, CV; Jackson, RJ,期刊：EMBO journal, 页码：3710-3722 , 文章类型： Article，,卷期：2010年29-21] Tethered hydroxyl-radical probing has been used to determine the orientation of binding of polypyrimidine tract-binding protein (PTB) to the poliovirus type 1 (Mahoney) (PV-1(M)) internal ribosome entry site/segment (IRE... TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint [作者：Cescutti, R; Negrini, S; Kohzaki, M; Halazonetis, TD,期刊：EMBO journal, 页码：3723-3732 , 文章类型： Article，,卷期：2010年29-21] TopBP1 is a checkpoint protein that colocalizes with ATR at sites of DNA replication stress. In this study, we show that TopBP1 also colocalizes with 53BP1 at sites of DNA double-strand breaks (DSBs), but only in the G1-... The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27 [作者：Zhang, ZG; Kulkarni, K; Hanrahan, SJ; Thompson, AJ; Barford, D,期刊：EMBO journal, 页码：3733-3744 , 文章类型： Article，,卷期：2010年29-21] The anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase responsible for controlling cell cycle transitions, is a multisubunit complex assembled from 13 different proteins. Numerous APC/C subunits incorpo... Cellular pathways controlling integron cassette site folding (vol 29, pg 2623, 2010) [作者：Loot, C; Bikard, D; Rachlin, A; Mazel, D,期刊：EMBO journal, 页码：3745-3745 , 文章类型： Correction，,卷期：2010年29-21]