- Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors
[作者：Kroehne, V; Freudenreich, D; Hans, S; Kaslin, J; Brand, M,期刊：Development, 页码：4831-4841 , 文章类型： Article，,卷期：2011年138-22]
- Severe traumatic injury to the adult mammalian CNS leads to life-long loss of function. By contrast, several non-mammalian vertebrate species, including adult zebrafish, have a remarkable ability to regenerate injured or...
- Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury
[作者：Mardaryev, AN; Meier, N; Poterlowicz, K; Sharov, AA; Sharova, TY; Ahmed, MI; Rapisarda, V; Lewis, C; Fessing, MY; Ruenger, TM; Bhawan, J; Werner, S; Paus, R; Botchkarev, VA,期刊：Development, 页码：4843-4852 , 文章类型： Article，,卷期：2011年138-22]
- The Lhx2 transcription factor plays essential roles in morphogenesis and patterning of ectodermal derivatives as well as in controlling stem cell activity. Here, we show that during murine skin morphogenesis, Lhx2 is exp...
- Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain
[作者：Theunissen, TW; Costa, Y; Radzisheuskaya, A; van Oosten, AL; Lavial, F; Pain, B; Castro, LFC; Silva, JCR,期刊：Development, 页码：4853-4865 , 文章类型： Article，,卷期：2011年138-22]
- Pluripotency is a developmental ground state that can be recreated by direct reprogramming. Establishment of pluripotency is crucially dependent on the homeodomain-containing transcription factor Nanog. Compared with oth...
- A computational statistics approach for estimating the spatial range of morphogen gradients
[作者：Kanodia, JS; Kim, Y; Tomer, R; Khan, Z; Chung, KH; Storey, JD; Lu, H; Keller, PJ; Shvartsman, SY,期刊：Development, 页码：4867-4874 , 文章类型： Article，,卷期：2011年138-22]
- A crucial issue in studies of morphogen gradients relates to their range: the distance over which they can act as direct regulators of cell signaling, gene expression and cell differentiation. To address this, we present...
- Rspo1/Wnt signaling promotes angiogenesis via Vegfc/Vegfr3
[作者：Gore, AV; Swift, MR; Cha, YR; Lo, B; McKinney, MC; Li, WL; Castranova, D; Davis, A; Mukouyama, YS; Weinstein, BM,期刊：Development, 页码：4875-4886 , 文章类型： Article，,卷期：2011年138-22]
- Here, we show that a novel Rspo1-Wnt-Vegfc-Vegfr3 signaling pathway plays an essential role in developmental angiogenesis. A mutation in R-spondin1 (rspo1), a Wnt signaling regulator, was uncovered during a forward-genet...
- Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery
[作者：Hancock, ML; Nowakowski, DW; Role, LW; Talmage, DA; Flanagan, JG,期刊：Development, 页码：4887-4898 , 文章类型： Article，,卷期：2011年138-22]
- Sensory axons must develop appropriate connections with both central and peripheral targets. Whereas the peripheral cues have provided a classic model for neuron survival and guidance, less is known about the central cue...
- Complex functions of Mef2 splice variants in the differentiation of endoderm and of a neuronal cell type in a sea anemone
[作者：Genikhovich, G; Technau, U,期刊：Development, 页码：4911-4919 , 文章类型： Article，,卷期：2011年138-22]
- In triploblastic animals, mesoderm gives rise to many tissues and organs, including muscle. By contrast, the representatives of the diploblastic phylum Cnidaria (corals, sea anemones, jellyfish and hydroids) lack mesoder...
- HESX1-and TCF3-mediated repression of Wnt/beta-catenin targets is required for normal development of the anterior forebrain
[作者：Andoniadou, CL; Signore, M; Young, RM; Gaston-Massuet, C; Wilson, SW; Fuchs, E; Martinez-Barbera, JP,期刊：Development, 页码：4931-4942 , 文章类型： Article，,卷期：2011年138-22]
- The Wnt/beta-catenin pathway plays an essential role during regionalisation of the vertebrate neural plate and its inhibition in the most anterior neural ectoderm is required for normal forebrain development. Hesx1 is a ...
- miR-124 function during Ciona intestinalis neuronal development includes extensive interaction with the Notch signaling pathway
[作者：Chen, JS; Pedro, MS; Zeller, RW,期刊：Development, 页码：4943-4953 , 文章类型： Article，,卷期：2011年138-22]
- The nervous system-enriched microRNA miR-124 is necessary for proper nervous system development, although the mechanism remains poorly understood. Here, through a comprehensive analysis of miR-124 and its gene targets, w...
- Erect Wing facilitates context-dependent Wnt/Wingless signaling by recruiting the cell-specific Armadillo-TCF adaptor Earthbound to chromatin
[作者：Xin, N; Benchabane, H; Tian, A; Nguyen, K; Klofas, L; Ahmed, Y,期刊：Development, 页码：4955-4967 , 文章类型： Article，,卷期：2011年138-22]
- During metazoan development, the Wnt/Wingless signal transduction pathway is activated repetitively to direct cell proliferation, fate specification, differentiation and apoptosis. Distinct outcomes are elicited by Wnt s...
- Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates
[作者：Ben, J; Elworthy, S; Ng, ASM; van Eeden, F; Ingham, PW,期刊：Development, 页码：4969-4978 , 文章类型： Article，,卷期：2011年138-22]
- Using zinc-finger nuclease-mediated mutagenesis, we have generated mutant alleles of the zebrafish orthologue of the chicken talpid3 (ta3) gene, which encodes a centrosomal protein that is essential for ciliogenesis. Ani...
- Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex
[作者：Watanabe, K; Takebayashi, H; Bepari, AK; Esumi, S; Yanagawa, Y; Tamamaki, N,期刊：Development, 页码：4979-4990 , 文章类型： Article，,卷期：2011年138-22]
- During corticogenesis, the regulation of neuronal migration is crucial for the functional organization of the neocortex. Glutamatergic neurons are major excitatory components of the mammalian neocortex. In order to eluci...
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