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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共24条记录   Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo [作者：Migeotte, I; Grego-Bessa, J; Anderson, KV,期刊：Development, 页码：3011-3020 , 文章类型： Article，,卷期：2011年138-14] The establishment of the mammalian body plan depends on signal-regulated cell migration and adhesion, processes that are controlled by the Rho family of GTPases. Here we use a conditional allele of Rac1, the only Rac gen... Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila [作者：Kolahgar, G; Bardet, PL; Langton, PF; Alexandre, C; Vincent, JP,期刊：Development, 页码：3021-3031 , 文章类型： Article，,卷期：2011年138-14] Epithelial homeostasis and the avoidance of diseases such as cancer require the elimination of defective cells by apoptosis. Here, we investigate how loss of apical determinants triggers apoptosis in the embryonic epider... Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration [作者：Walsh, GS; Grant, PK; Morgan, JA; Moens, CB,期刊：Development, 页码：3033-3042 , 文章类型： Article，,卷期：2011年138-14] Components of the planar cell polarity (PCP) pathway are required for the caudal tangential migration of facial branchiomotor (FBM) neurons, but how PCP signaling regulates this migration is not understood. In a forward ... Spatial, temporal and molecular hierarchies in the link between death, delamination and dorsal closure [作者：Muliyil, S; Krishnakumar, P; Narasimha, M,期刊：Development, 页码：3043-3054 , 文章类型： Article，,卷期：2011年138-14] Dead cells in most epithelia are eliminated by cell extrusion. Here, we explore whether cell delamination in the amnioserosa, a seemingly stochastic event that results in the extrusion of a small fraction of cells and kn... Msx genes define a population of mural cell precursors required for head blood vessel maturation [作者：Lopes, M; Goupille, O; Saint Cloment, C; Lallemand, Y; Cumano, A; Robert, B,期刊：Development, 页码：3055-3066 , 文章类型： Article，,卷期：2011年138-14] Vessels are primarily formed from an inner endothelial layer that is secondarily covered by mural cells, namely vascular smooth muscle cells (VSMCs) in arteries and veins and pericytes in capillaries and veinules. We pre... How to make stripes: deciphering the transition from non-periodic to periodic patterns in Drosophila segmentation [作者：Schroeder, MD; Greer, C; Gaul, U,期刊：Development, 页码：3067-3078 , 文章类型： Article，,卷期：2011年138-14] The generation of metameric body plans is a key process in development. In Drosophila segmentation, periodicity is established rapidly through the complex transcriptional regulation of the pair-rule genes. The 'primary' ... hnRNP K post-transcriptionally co-regulates multiple cytoskeletal genes needed for axonogenesis [作者：Liu, YY; Szaro, BG,期刊：Development, 页码：3079-3090 , 文章类型： Article，,卷期：2011年138-14] The RNA-binding protein, hnRNP K, is essential for axonogenesis. Suppressing its expression in Xenopus embryos yields terminally specified neurons with severely disorganized microtubules, microfilaments and neurofilament... The transcription factor FoxB mediates temporal loss of cellular competence for notochord induction in ascidian embryos (vol 138, pg 2591, 2011) [作者：Hashimoto, H; Enomoto, T; Kumano, G; Nishida, H,期刊：Development, 页码：3091-3091 , 文章类型： Correction，,卷期：2011年138-14] Development of the musculoskeletal system: meeting the neighbors [作者：Kardon, G,期刊：Development, 页码：2855-2859 , 文章类型： Editorial Material，,卷期：2011年138-14] In March 2011, researchers met for the second Batsheva Seminar on Integrative Perspectives on the Development of the Musculoskeletal System. This meeting was a unique opportunity for researchers working on muscle, connec... The stem cell niche: lessons from the Drosophila testis [作者：de Cuevas, M; Matunis, EL,期刊：Development, 页码：2861-2869 , 文章类型： Review，,卷期：2011年138-14] In metazoans, tissue maintenance and regeneration depend on adult stem cells, which are characterized by their ability to self-renew and generate differentiating progeny in response to the needs of the tissues in which t... Ci-Pem-1 localizes to the nucleus and represses somatic gene transcription in the germline of Ciona intestinalis embryos [作者：Shirae-Kurabayashi, M; Matsuda, K; Nakamura, A,期刊：Development, 页码：2871-2881 , 文章类型： Article，,卷期：2011年138-14] In many animal embryos, germ-cell formation depends on maternal factors located in the germ plasm. To ensure the development of germ cells, germline progenitors must be prevented from differentiating inappropriately into... Serial specification of diverse neuroblast identities from a neurogenic placode by Notch and Egfr signaling [作者：Hwang, HJ; Rulifson, E,期刊：Development, 页码：2883-2893 , 文章类型： Article，,卷期：2011年138-14] We used the brain insulin-producing cell (IPC) lineage and its identified neuroblast (IPC NB) as a model to understand a novel example of serial specification of NB identities in the Drosophila dorsomedial protocerebral ... tcf21(+) epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration [作者：Kikuchi, K; Gupta, V; Wang, JH; Holdway, JE; Wills, AA; Fang, Y; Poss, KD,期刊：Development, 页码：2895-2902 , 文章类型： Article，,卷期：2011年138-14] Recent lineage-tracing studies have produced conflicting results about whether the epicardium is a source of cardiac muscle cells during heart development. Here, we examined the developmental potential of epicardial tiss... Symmetry breaking in mouse oocytes requires transient F-actin meshwork destabilization [作者：Azoury, J; Lee, KW; Georget, V; Hikal, P; Verlhac, MH,期刊：Development, 页码：2903-2908 , 文章类型： Article，,卷期：2011年138-14] Female meiotic divisions are extremely asymmetric, giving rise to a large oocyte and small degenerating polar bodies, keeping the maternal stores for further embryo development. This asymmetry is achieved via off-center ... Cxcl12 evolution - subfunctionalization of a ligand through altered interaction with the chemokine receptor [作者：Boldajipour, B; Doitsidou, M; Tarbashevich, K; Laguri, C; Yu, SR; Ries, J; Dumstrei, K; Thelen, S; Dorries, J; Messerschmidt, EM; Thelen, M; Schwille, P; Brand, M; Lortat-Jacob, H; Raz, E,期刊：Development, 页码：2909-2914 , 文章类型： Article，,卷期：2011年138-14] The active migration of primordial germ cells (PGCs) from their site of specification towards their target is a valuable model for investigating directed cell migration within the complex environment of the developing em... Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein [作者：Harterink, M; Kim, DH; Middelkoop, TC; Doan, TD; van Oudenaarden, A; Korswagen, HC,期刊：Development, 页码：2915-2924 , 文章类型： Article，,卷期：2011年138-14] The migration of neuroblasts along the anteroposterior body axis of C. elegans is controlled by multiple Wnts that act partially redundantly to guide cells to their precisely defined final destinations. How positional in...