- Blind Testing of Routine, Fully Automated Determination of Protein Structures from NMR Data
[作者：Rosato, A; Aramini, JM; Arrowsmith, C; Bagaria, A; Baker, D; Cavalli, A; Doreleijers, JF; Eletsky, A; Giachetti, A; Guerry, P; Gutmanas, A; Guntert, P; He, YF; Herrmann, T; Huang, YPJ; Jaravine, V; Jonker, HRA; Kennedy, MA; Lange, OF; Liu, GH; Malliavin, TE; Mani, R; Mao, BC; Montelione, GT; Nilges, M; Rossi, P; van der Schot, G; Schwalbe, H; Szyperski, TA; Vendruscolo, M; Vernon, R; Vranken, WF; de Vries, S; Vuister, GW; Wu, B; Yang, YH; Bonvin, AMJJ,期刊：Structure, 页码：227-236 , 文章类型： Article，,卷期：2012年20-2]
- The protocols currently used for protein structure determination by nuclear magnetic resonance (NMR) depend on the determination of a large number of upper distance limits for proton-proton pairs. Typically, this task is...
- Iterative Stable Alignment and Clustering of 2D Transmission Electron Microscope Images
[作者：Yang, ZF; Fang, J; Chittuluru, J; Asturias, FJ; Penczek, PA,期刊：Structure, 页码：237-247 , 文章类型： Article，,卷期：2012年20-2]
- Identification of homogeneous subsets of images in a macromolecular electron microscopy (EM) image data set is a critical step in single-particle analysis. The task is handled by iterative algorithms, whose performance i...
- Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity
[作者：Feil, SC; Lawrence, S; Mulhern, TD; Holien, JK; Hotze, EM; Farrand, S; Tweten, RK; Parker, MW,期刊：Structure, 页码：248-258 , 文章类型： Article，,卷期：2012年20-2]
- The cholesterol-dependent cytolysins (CDCs) punch holes in target cell membranes through a highly regulated process. Streptococcus mitis lectinolysin (LLY) exhibits another layer of regulation with a lectin domain that e...
- Structures of Adnectin/Protein Complexes Reveal an Expanded Binding Footprint
[作者：Ramamurthy, V; Krystek, SR; Bush, A; Wei, AZ; Emanuel, SL; Das Gupta, R; Janjua, A; Cheng, L; Murdock, M; Abramczyk, B; Cohen, D; Lin, Z; Morin, P; Davis, JH; Dabritz, M; McLaughlin, DC; Russo, KA; Chao, G; Wright, MC; Jenny, VA; Engle, LJ; Furfine, E; Sheriff, S,期刊：Structure, 页码：259-269 , 文章类型： Article，,卷期：2012年20-2]
- Adnectins are targeted biologics derived from the tenth type III domain of human fibronectin ((10)Fn3), a member of the immunoglobulin superfamily. Target-specific binders are selected from libraries generated by diversi...
- The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor
[作者：Dagil, R; Knudsen, MJ; Olsen, JG; O'Shea, C; Franzmann, M; Goffin, V; Teilum, K; Breinholt, J; Kragelund, BB,期刊：Structure, 页码：270-282 , 文章类型： Article，,卷期：2012年20-2]
- The prolactin receptor (PRLR) is activated by binding of prolactin in a 2:1 complex, but the activation mechanism is poorly understood. PRLR has a conserved WSXWS motif generic to cytokine class I receptors. We have dete...
- Mutational Tipping Points for Switching Protein Folds and Functions
[作者：He, YA; Chen, YH; Alexander, PA; Bryan, PN; Orban, J,期刊：Structure, 页码：283-291 , 文章类型： Article，,卷期：2012年20-2]
- While disordered to ordered rearrangements are relatively common, the ability of proteins to switch from one ordered fold to a completely different fold is generally regarded as rare, and few fold switches have been char...
- Allosterically Gated Enzyme Dynamics in the Cysteine Synthase Complex Regulate Cysteine Biosynthesis in Arabidopsis thaliana
[作者：Feldman-Salit, A; Wirtz, M; Lenherr, ED; Throm, C; Hothorn, M; Scheffzek, K; Hell, R; Wade, RC,期刊：Structure, 页码：292-302 , 文章类型： Article，,卷期：2012年20-2]
- Plants and bacteria assimilate sulfur into cysteine. Cysteine biosynthesis involves a bienzyme complex, the cysteine synthase complex (CSC), which consists of serine-acetyl-transferase (SAT) and O-acetylserine-(thiol)-ly...
- Mechanism of Dengue Virus Broad Cross-Neutralization by a Monoclonal Antibody
[作者：Cockburn, JJB; Sanchez, MEN; Fretes, N; Urvoas, A; Staropoli, I; Kikuti, CM; Coffey, LL; Seisdedos, FA; Bedouelle, H; Rey, FA,期刊：Structure, 页码：303-314 , 文章类型： Article，,卷期：2012年20-2]
- The dengue virus (DENV) complex is composed of four distinct but serologically related flaviviruses, which together cause the present-day most important emerging viral disease. Although DENV infection induces lifelong im...
- Multiple Conformations of the FliG C-Terminal Domain Provide Insight into Flagellar Motor Switching
[作者：Lam, KH; Ip, WS; Lam, YW; Chan, SO; Ling, TKW; Au, SWN,期刊：Structure, 页码：315-325 , 文章类型： Article，,卷期：2012年20-2]
- Bacterial flagellar switching between counterclockwise and clockwise directions is mediated by the coupling of the chemotactic system and the motor switch complex. The conformational changes of FliG are closely associate...
- Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike
[作者：Browning, C; Shneider, MM; Bowman, VD; Schwarzer, D; Leiman, PG,期刊：Structure, 页码：326-339 , 文章类型： Article，,卷期：2012年20-2]
- Bacteriophages with contractile tails and the bacterial type VI secretion system have been proposed to use a special protein to create an opening in the host cell membrane during infection. These proteins have a modular ...
- Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes
[作者：Choi, SH; Wales, TE; Nam, Y; O'Donovan, DJ; Sliz, P; Engen, JR; Blacklow, SC,期刊：Structure, 页码：340-349 , 文章类型： Article，,卷期：2012年20-2]
- The Notch intracellular domain (NICD) forms a transcriptional activation complex with the DNA-binding factor CSL and a transcriptional co-activator of the Mastermind family (MAML). The "RAM" region of NICD recruits Notch...
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