- Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells
[作者:Higashimura, Y; Nakajima, Y; Yamaji, R; Harada, N; Shibasaki, F; Nakano, Y; Inui, H,期刊:Archives of Biochemistry and Biophysics , 页码:1-8 , 文章类型: Article,,卷期:2011年509-1]
- Hypoxia up-regulates the expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in a cell type-specific manner. It is unknown whether this occurs in breast cancer. Here, we report that hypoxia up-regulates the GA...
- Heterologous expression and characterization of the sterol 14 alpha-demethylase CYP51F1 from Candida albicans
[作者:Park, HG; Lee, IS; Chun, YJ; Yun, CH; Johnston, JB; de Montellano, PRO; Kim, D,期刊:Archives of Biochemistry and Biophysics , 页码:9-15 , 文章类型: Article,,卷期:2011年509-1]
- Lanosterol 14 alpha-demethylase (CYP51F1) from Candida albicans is known to be an essential enzyme in fungal sterol biosynthesis. Wild-type CYP51F1 and several of its mutants were heterologously expressed in Escherichia ...
- Hypochlorite-modified high-density lipoprotein promotes induction of HO-1 in endothelial cells via activation of p42/44 MAPK and zinc finger transcription factor Egr-1
[作者:Rossmann, C; Rauh, A; Hammer, A; Windischhofer, W; Zirkl, S; Sattler, W; Malle, E,期刊:Archives of Biochemistry and Biophysics , 页码:16-25 , 文章类型: Article,,卷期:2011年509-1]
- Modification/chlorination of high-density lipoprotein (HDL) by hypochlorous acid (HOCl), formed by the myeloperoxidase-H2O2-chloride system of activated phagocytes, converts an anti-atherogenic lipoprotein into a pro-inf...
- Cytochrome b(5) reductase-cytochrome b(5) as an active P450 redox enzyme system in Phanerochaete chrysosporium: Atypical properties and in vivo evidence of electron transfer capability to CYP63A2
[作者:Syed, K; Kattamuri, C; Thompson, TB; Yadav, JS,期刊:Archives of Biochemistry and Biophysics , 页码:26-32 , 文章类型: Article,,卷期:2011年509-1]
- Two central redox enzyme systems exist to reduce eukaryotic P450 enzymes, the P450 oxidoreductase (POR) and the cyt b(5) reductase-cyt b(5). In fungi, limited information is available for the cyt b(5) reductase-cyt b(5) ...
- A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1 alpha,25-dihydroxyvitamin D-3
[作者:Rhieu, SY; Annalora, AJ; Gathungu, RM; Vouros, P; Uskokovic, MR; Schuster, I; Palmore, GTR; Reddy, GS,期刊:Archives of Biochemistry and Biophysics , 页码:33-43 , 文章类型: Article,,卷期:2011年509-1]
- We examined the metabolism of two synthetic analogs of 1 alpha,25-dihydroxyvitamin D-3 (1), namely 1 alpha,25-dihydroxy-16-ene-23-yne-vitamin D-3 (2) and 1 alpha,25-dihydroxy-16-ene-23-yne-26,27-dimethyl-vitamin D-3 (4) ...
- Characterization of the regulatory subunit of Yarrowia lipolytica cAMP-dependent protein kinase. Evidences of a monomeric protein
[作者:Kronberg, F; Giacometti, R; Ruiz-Herrera, J; Passeron, S,期刊:Archives of Biochemistry and Biophysics , 页码:66-75 , 文章类型: Article,,卷期:2011年509-1]
- cAMP-dependent protein kinase (PKA) catalytic (C) and regulatory (R) subunits from Yarrowia lipolytica are encoded by single genes, TPK1 and RKA1, respectively. Here we performed the heterologous expression, purification...
- Crystal structure and immunogenicity of the class C acid phosphatase from Pasteurella multocida
[作者:Singh, H; Malinski, TJ; Reilly, TJ; Henzl, MT; Tanner, JJ,期刊:Archives of Biochemistry and Biophysics , 页码:76-81 , 文章类型: Article,,卷期:2011年509-1]
- Pasteurella multocida is a pathogen of veterinary and medical importance. Here, we report the 1.85 angstrom resolution crystal structure of the class C acid phosphatase from this organism (denoted rPmCCAP). The structure...
- Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies
[作者:Palmieri-Thiers, C; Alberti, JC; Canaan, S; Brunini, V; Gambotti, C; Tomi, F; Oliw, EH; Berti, L; Maury, J,期刊:Archives of Biochemistry and Biophysics , 页码:82-89 , 文章类型: Article,,卷期:2011年509-1]
- Lipoxygenases (LOXs) are a class of widespread dioxygenases catalyzing the hydroperoxidation of polyunsaturated fatty acids (PUFA). Recently, we isolated a cDNA encoding a LOX, named olive LOX1, from olive fruit of which...
- On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis
[作者:de Carvalho, LPS; Ling, Y; Shen, C; Warren, JD; Rhee, KY,期刊:Archives of Biochemistry and Biophysics , 页码:90-99 , 文章类型: Article,,卷期:2011年509-1]
- Succinic semialdehyde dehydrogenases (SSADHs) are ubiquitous enzymes that catalyze the NAD(P)(+)-coupled oxidation of succinic semialdehyde (SSA) to succinate, the last step of the gamma-aminobutyrate shunt. Mycobacteriu...
- Characterization of Ceriporiopsis subvermispora bicupin oxalate oxidase expressed in Pichia pastoris
[作者:Moussatche, P; Angerhofer, A; Imaram, W; Hoffer, E; Uberto, K; Brooks, C; Bruce, C; Sledge, D; Richards, NGJ; Moomaw, EW,期刊:Archives of Biochemistry and Biophysics , 页码:100-107 , 文章类型: Article,,卷期:2011年509-1]
- Oxalate oxidase (E.C. 1.2.3.4) catalyzes the oxygen-dependent oxidation of oxalate to carbon dioxide in a reaction that is coupled with the formation of hydrogen peroxide. Although there is currently no structural inform...
- Crystal structure determination and dynamic studies of Mycobacterium tuberculosis Cytidine deaminase in complex with products
[作者:Sanchez-Quitian, ZA; Timmers, LFSM; Caceres, RA; Rehm, JG; Thompson, CE; Basso, LA; de Azevedo, WF; Santos, DS,期刊:Archives of Biochemistry and Biophysics , 页码:108-115 , 文章类型: Article,,卷期:2011年509-1]
- Cytidine deaminase (CDA) is a key enzyme in the pyrimidine salvage pathway. It is involved in the hydrolytic deamination of cytidine or 2'-deoxycytidine to uridine or 2'-deoxyuridine, respectively. Here we report the cry...
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