- Molecular Identification and Functional Characterization of a Mitochondrial Sulfonylurea Receptor 2 Splice Variant Generated by Intraexonic Splicing
[作者：Ye, B; Kroboth, SL; Pu, JL; Sims, JJ; Aggarwal, NT; McNally, EM; Makielski, JC; Shi, NQ,期刊：Circulation Research, 页码：1083-U99 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: Cardioprotective pathways may involve a mitochondrial ATP-sensitive potassium (mitoK(ATP)) channel but its composition is not fully understood. Objective: We hypothesized that the mitoK(ATP) channel contains a...
- Conditional Ablation of Nonmuscle Myosin II-B Delineates Heart Defects in Adult Mice
[作者：Ma, XF; Takeda, K; Singh, A; Yu, ZX; Zerfas, P; Blount, A; Liu, CY; Towbin, JA; Schneider, MD; Adelstein, RS; Wei, QZ,期刊：Circulation Research, 页码：1102-U128 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: Germline ablation of the cytoskeletal protein nonmuscle myosin II (NMII)-B results in embryonic lethality, with defects in both the brain and heart. Tissue-specific ablation of NMII-B by a Cre recombinase stra...
- Metabolic Remodeling Induced by Mitochondrial Aldehyde Stress Stimulates Tolerance to Oxidative Stress in the Heart
[作者：Endo, J; Sano, M; Katayama, T; Hishiki, T; Shinmura, K; Morizane, S; Matsuhashi, T; Katsumata, Y; Zhang, Y; Ito, H; Nagahata, Y; Marchitti, S; Nishimaki, K; Wolf, AM; Nakanishi, H; Hattori, F; Vasiliou, V; Adachi, T; Ohsawa, I; Taguchi, R; Hirabayashi, Y; Ohta, S; Suematsu, M; Ogawa, S; Fukuda, K,期刊：Circulation Research, 页码：1118-U170 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: Aldehyde accumulation is regarded as a pathognomonic feature of oxidative stress-associated cardiovascular disease. Objective: We investigated how the heart compensates for the accelerated accumulation of alde...
- Progenitor Cells From the Explanted Heart Generate Immunocompatible Myocardium Within the Transplanted Donor Heart
[作者：D'Alessandro, DA; Kajstura, J; Hosoda, T; Gatti, A; Bello, R; Mosna, F; Bardelli, S; Zheng, HQ; D'Amario, D; Padin-Iruegas, ME; Carvalho, AB; Rota, M; Zembala, MO; Stern, D; Rimoldi, O; Urbanek, K; Michler, RE; Leri, A; Anversa, P,期刊：Circulation Research, 页码：1128-U221 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: Chronic rejection, accelerated coronary atherosclerosis, myocardial infarction, and ischemic heart failure determine the unfavorable evolution of the transplanted heart in humans. Objective: Here we tested whe...
- Discoidin Domain Receptor 1 on Bone Marrow-Derived Cells Promotes Macrophage Accumulation During Atherogenesis
[作者：Franco, C; Britto, K; Wong, E; Hou, GP; Zhu, SN; Chen, M; Cybulsky, MI; Bendeck, MP,期刊：Circulation Research, 页码：1141-U238 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: We described a critical role for the discoidin domain receptor (DDR) 1 collagen receptor tyrosine kinase during atherosclerotic plaque development. Systemic deletion of Ddr1 in Ldlr(-/-) mice accelerated matri...
- Pressure-Mediated Hypertrophy and Mechanical Stretch Induces IL-1 Release and Subsequent IGF-1 Generation to Maintain Compensative Hypertrophy by Affecting Akt and JNK Pathways
[作者：Honsho, S; Nishikawa, S; Amano, K; Zen, K; Adachi, Y; Kishita, E; Matsui, A; Katsume, A; Yamaguchi, S; Nishikawa, K; Isoda, K; Riches, DWH; Matoba, S; Okigaki, M; Matsubara, H,期刊：Circulation Research, 页码：1149-U265 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: It has been reported that interleukin (IL)-1 is associated with pathological cardiac remodeling and LV dilatation, whereas IL-1 beta has also been shown to induce cardiomyocyte hypertrophy. Thus, the role of I...
- Spiral Waves and Reentry Dynamics in an In Vitro Model of the Healed Infarct Border Zone
[作者：Chang, MG; Zhang, YB; Chang, CY; Xu, LM; Emokpae, R; Tung, L; Marban, E; Abraham, MR,期刊：Circulation Research, 页码：1062-U56 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: Reentry underlies most ventricular tachycardias (VTs) seen postmyocardial infarction (MI). Mapping studies reveal that the majority of VTs late post-MI arise from the infarct border zone (IBZ). Objective: To i...
- Defective Phagocytosis of Apoptotic Cells by Macrophages in Atherosclerotic Lesions of ob/ob Mice and Reversal by a Fish Oil Diet
[作者：Li, SZ; Sun, Y; Liang, CP; Thorp, EB; Han, S; Jehle, AW; Saraswathi, V; Pridgen, B; Kanter, JE; Li, R; Welch, CL; Hasty, AH; Bornfeldt, KE; Breslow, JL; Tabas, I; Tall, AR,期刊：Circulation Research, 页码：1072-U82 , 文章类型： Article，,卷期：2009年105-11]
- Rationale: The complications of atherosclerosis are a major cause of death and disability in type 2 diabetes. Defective clearance of apoptotic cells by macrophages (efferocytosis) is thought to lead to increased necrotic...
|