- Lipid cubic phases in topical drug delivery: Visualization of skin distribution using two-photon microscopy
[作者:Bender, J; Simonsson, C; Smedh, M; Engstrom, S; Ericson, MB,期刊:Journal of controlled release, 页码:163-169 , 文章类型: Article,,卷期:2008年129-3]
- The distribution of sulphorhodamine B (SRB), a fluorescent hydrophilic model drug, was investigated in human skin after passive diffusion using four different topical delivery systems. The delivery vehicles applied were ...
- Development of a reservoir-type transdermal enantioselective-controlled delivery system for racemic propranolol using a molecularly imprinted polymer composite membrane
[作者:Suedee, R; Bodhibukkana, C; Tangthong, N; Amnuaikit, C; Kaewnopparat, S; Srichana, T,期刊:Journal of controlled release, 页码:170-178 , 文章类型: Article,,卷期:2008年129-3]
- The aims of this study were to develop a transdermal patch for selective controlled delivery of the active S-enantiomer from racemic propranolol, and to evaluate its performance in vivo using Wistar rats. A molecularly i...
- Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist
[作者:Shamji, MF; Chen, J; Friedman, AH; Richardson, WJ; Chilkoti, A; Setton, LA,期刊:Journal of controlled release, 页码:179-186 , 文章类型: Article,,卷期:2008年129-3]
- Numerous antagonists of tumor necrosis factor alpha (TNF alpha) have been developed to attenuate inflammation and accompanying pain in many disease processes. Soluble TNF receptor type II (sTNFRII) is one such antagonist...
- Healing of articular cartilage defects treated with a novel drug-releasing rod-type implant after microfracture surgery
[作者:Shim, IK; Yook, YJ; Lee, SY; Lee, SH; Park, KD; Lee, MC; Lee, SJ,期刊:Journal of controlled release, 页码:187-191 , 文章类型: Article,,卷期:2008年129-3]
- Microfracture therapy is a widely used technique for the repair of articular cartilage defects because it can be readily performed arthroscopically. However, the regenerated cartilage after microfracture surgery clearly ...
- Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance
[作者:Lee, ES; Gao, ZG; Kim, D; Park, K; Kwon, IC; Bae, YH,期刊:Journal of controlled release, 页码:228-236 , 文章类型: Article,,卷期:2008年129-3]
- As an alternative to cell specific cancer targeting strategies (which are often afflicted with the heterogeneity of cancer cells as with most biological systems), a novel polymeric micelle constitute of two block copolym...
- Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: Potential for enhanced topical photodynamic therapy
[作者:Donnelly, RF; Morrow, DIJ; McCarron, PA; Woolfson, AD; Morrissey, A; Juzenas, P; Juzeniene, A; Iani, V; McCarthy, HO; Moan, J,期刊:Journal of controlled release, 页码:154-162 , 文章类型: Article,,卷期:2008年129-3]
- Photodynamic therapy of deep or nodular skin tumours is currently limited by the poor tissue penetration of the porphyrin precursor 5-aminolevulinic acid (ALA). In this study, silicon microneedle arrays were used, for th...
- Synchronic release of two hormonal contraceptives for about one month from the PLGA microspheres: In vitro and in vivo studies
[作者:Sun, Y; Wang, JC; Zhang, X; Zhang, ZJ; Zheng, Y; Chen, DW; Zhang, Q,期刊:Journal of controlled release, 页码:192-199 , 文章类型: Article,,卷期:2008年129-3]
- A controlled drug release system based on the injectable PLGA microspheres loaded with gestodene and ethinyl estradiol was prepared and evaluated for the feasibility of monthly synchronic delivery of the two hormonal con...
- Non-toxic phototriggered gene transfection by PAMAM-porphyrin conjugates
[作者:Shieh, MJ; Peng, CL; Lou, PJ; Chiu, CH; Tsai, TY; Hsu, CY; Yeh, CY; Lai, PS,期刊:Journal of controlled release, 页码:200-206 , 文章类型: Article,,卷期:2008年129-3]
- Development of controllable and non-toxic gene transfection systems is a core issue in gene therapy. Photochemical internalization, an innovative strategy in cytosolic release, provides us with an opportunity to develop ...
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