- Concerted action of two cation filters in the aquaporin water channel
[作者:Wu, BH; Steinbronn, C; Alsterfjord, M; Zeuthen, T; Beitz, E,期刊:EMBO journal, 页码:2188-2194 , 文章类型: Article,,卷期:2009年28-15]
- Aquaporin (AQP) facilitated water transport is common to virtually all cell membranes and is marked by almost perfect specificity and high flux rates. Simultaneously, protons and cations are strictly excluded to maintain...
- Crosstalk between GABA(B) and mGlu1a receptors reveals new insight into GPCR signal integration
[作者:Rives, ML; Vol, C; Fukazawa, Y; Tinel, N; Trinquet, E; Ayoub, MA; Shigemoto, R; Pin, JP; Prezeau, L,期刊:EMBO journal, 页码:2195-2208 , 文章类型: Article,,卷期:2009年28-15]
- G protein-coupled receptors (GPCRs) have critical functions in intercellular communication. Although a wide range of different receptors have been identified in the same cells, the mechanism by which signals are integrat...
- Increased RNA polymerase availability directs resources towards growth at the expense of maintenance
[作者:Gummesson, B; Magnusson, LU; Lovmar, M; Kvint, K; Persson, O; Ballesteros, M; Farewell, A; Nystrom, T,期刊:EMBO journal, 页码:2209-2219 , 文章类型: Article,,卷期:2009年28-15]
- Nutritionally induced changes in RNA polymerase availability have been hypothesized to be an evolutionary primeval mechanism for regulation of gene expression and several contrasting models have been proposed to explain ...
- Transcriptional competence of the integrated HIV-1 provirus at the nuclear periphery
[作者:Dieudonne, M; Maiuri, P; Biancotto, C; Knezevich, A; Kula, A; Lusic, M; Marcello, A,期刊:EMBO journal, 页码:2231-2243 , 文章类型: Article,,卷期:2009年28-15]
- Spatial distribution of genes within the nucleus contributes to transcriptional control, allowing optimal gene expression as well as constitutive or regulated gene repression. Human immunodeficiency virus type 1 (HIV-1) ...
- Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy
[作者:Vergne, I; Roberts, E; Elmaoued, RA; Tosch, V; Delgado, MA; Proikas-Cezanne, T; Laporte, J; Deretic, V,期刊:EMBO journal, 页码:2244-2258 , 文章类型: Article,,卷期:2009年28-15]
- The majority of studies on autophagy, a cytoplasmic homeostatis pathway of broad biological and medical significance, have been hitherto focused on the phosphatidylinositol 3-kinases as the regulators of autophagy. Here,...
- Localisation of DivIVA by targeting to negatively curved membranes
[作者:Lenarcic, R; Halbedel, S; Visser, L; Shaw, M; Wu, LJ; Errington, J; Marenduzzo, D; Hamoen, LW,期刊:EMBO journal, 页码:2272-2282 , 文章类型: Article,,卷期:2009年28-15]
- DivIVA is a conserved protein in Gram-positive bacteria and involved in various processes related to cell growth, cell division and spore formation. DivIVA is specifically targeted to cell division sites and cell poles. ...
- Exon, intron and splice site locations in the spliceosomal B complex
[作者:Wolf, E; Kastner, B; Deckert, J; Merz, C; Stark, H; Luhrmann, R,期刊:EMBO journal, 页码:2283-2292 , 文章类型: Article,,卷期:2009年28-15]
- In recent years, electron microscopy (EM) has allowed the generation of three-dimensional structure maps of several spliceosomal complexes. However, owing to their limited resolution, little is known at present about the...
- Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2
[作者:Clerici, M; Mourao, A; Gutsche, I; Gehring, NH; Hentze, MW; Kulozik, A; Kadlec, J; Sattler, M; Cusack, S,期刊:EMBO journal, 页码:2293-2306 , 文章类型: Article,,卷期:2009年28-15]
- Nonsense-mediated decay (NMD) is a eukaryotic quality control mechanism that degrades mRNAs carrying premature stop codons. In mammalian cells, NMD is triggered when UPF2 bound to UPF3 on a downstream exon junction compl...
- Gene activation at the edge of the nucleus
[作者:Chubb, JR,期刊:EMBO journal, 页码:2145-2146 , 文章类型: Article,,卷期:2009年28-15]
- The position of a gene within the nucleus can be a determinant of the level of gene activity. In recent years, particular emphasis has been placed on the nuclear envelope as a transcriptionally silent nuclear location. A...
- Irresistible curves
[作者:Juarez, JR; Margolin, W,期刊:EMBO journal, 页码:2147-2148 , 文章类型: Article,,卷期:2009年28-15]
- The DivIVA protein helps to organize cell growth and polarity in Gram-positive bacteria by localizing specifically to the cytoplasmic membrane at the cell poles and division septum, independent of other proteins. In this...
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