- Expression of microRNA 210 associates with poor survival and age of tumor onset of soft-tissue sarcoma patients
[作者:Greither, T; Wurl, P; Grochola, L; Bond, G; Bache, M; Kappler, M; Lautenschlager, C; Holzhausen, HJ; Wach, S; Eckert, AW; Taubert, H,期刊:International Journal of Cancer, 页码:1230-1235 , 文章类型: Article,,卷期:2012年130-5]
- Expression of microRNAs can affect age of tumor onset and prognosis of cancer patients. However, nothing is known about the effects of microRNAs on altered age of cancer onset and disease-specific survival of soft-tissue...
- Differential carcinogenicity of cigarette smoke in mice exposed either transplacentally, early in life or in adulthood
[作者:Balansky, R; Ganchev, G; Iltcheva, M; Nikolov, M; Steele, VE; De Flora, S,期刊:International Journal of Cancer, 页码:1001-1010 , 文章类型: Article,,卷期:2012年130-5]
- Cigarette smoke (CS) plays a dominant role in the epidemiology of human cancer. However, it is difficult to reproduce its carcinogenicity in laboratory animals. Recently, we showed that CS becomes a potent carcinogen in ...
- AP1B plays an important role in intestinal tumorigenesis with the truncating mutation of an APC gene
[作者:Mimura, M; Masuda, A; Nishiumi, S; Kawakami, K; Fujishima, Y; Yoshie, T; Mizuno, S; Miki, I; Ohno, H; Hase, K; Minamoto, T; Azuma, T; Yoshida, M,期刊:International Journal of Cancer, 页码:1011-1020 , 文章类型: Article,,卷期:2012年130-5]
- Recent evidence has suggested that carcinoma is accompanied by the loss of cell polarity. An epithelial cell-specific form of the AP-1 clathrin adaptor complex, AP1B, is involved in the polarized transport of membrane pr...
- Oct1 regulates cell growth of LNCaP cells and is a prognostic factor for prostate cancer
[作者:Obinata, D; Takayama, K; Urano, T; Murata, T; Kumagai, J; Fujimura, T; Ikeda, K; Horie-Inoue, K; Homma, Y; Ouchi, Y; Takahashi, S; Inoue, S,期刊:International Journal of Cancer, 页码:1021-1028 , 文章类型: Article,,卷期:2012年130-5]
- The androgen receptor (AR) plays a critical role in the development and the progression of prostate cancer. Alterations in the expression of AR coregulators lead to AR hypersensitivity, which is one of the mechanisms und...
- HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation
[作者:He, XP; Khurana, A; Maguire, JL; Chien, J; Shridhar, V,期刊:International Journal of Cancer, 页码:1029-1035 , 文章类型: Article,,卷期:2012年130-5]
- HtrA1, a member of serine protease family, has been previously found to be involved in resistance to chemotherapy in ovarian cancer although the underlying mechanism is not clear. Using mixture-based oriented peptide lib...
- Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1
[作者:Chung, TKH; Lau, TS; Cheung, TH; Yim, SF; Lo, KWK; Siu, NSS; Chan, LKY; Yu, MY; Kwong, J; Doran, G; Barroilhet, LM; Ng, ASW; Wong, RRY; Wang, VW; Mok, SC; Smith, DI; Berkowitz, RS; Wong, YF,期刊:International Journal of Cancer, 页码:1036-1045 , 文章类型: Article,,卷期:2012年130-5]
- MicroRNAs (miRNAs) regulate mRNA stability and protein expression, and certain miRNAs have been demonstrated to act either as oncogenes or tumor suppressors. Differential miRNA expression signatures have been documented ...
- Down-regulation of Thanatos-associated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression
[作者:Nakamura, S; Yokota, D; Tan, L; Nagata, Y; Takemura, T; Hirano, I; Shigeno, K; Shibata, K; Fujisawa, S; Ohnishi, K,期刊:International Journal of Cancer, 页码:1046-1059 , 文章类型: Article,,卷期:2012年130-5]
- Bcr-Abl activates various signaling pathways in chronic myelogenous leukemia (CML) cells. The proliferation of Bcr-Abl transformed cells is promoted by c-Myc through the activation of Akt, JAK2 and NF-?B. However, the me...
- Anomalous inhibition of c-Met by the kinesin inhibitor aurintricarboxylic acid
[作者:Milanovic, M; Radtke, S; Peel, N; Howell, M; Carriere, V; Joffre, C; Kermorgant, S; Parker, PJ,期刊:International Journal of Cancer, 页码:1060-1070 , 文章类型: Article,,卷期:2012年130-5]
- c-Met [the hepatocyte growth factor (HGF) receptor] is a receptor tyrosine kinase playing a role in various biological events. Overexpression of the receptor has been observed in a number of cancers, correlating with inc...
- D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the antioxidant enzyme MnSOD
[作者:Ganapathy, E; Su, F; Meriwether, D; Devarajan, A; Grijalva, V; Gao, F; Chattopadhyay, A; Anantharamaiah, GM; Navab, M; Fogelman, AM; Reddy, ST; Farias-Eisner, R,期刊:International Journal of Cancer, 页码:1071-1081 , 文章类型: Article,,卷期:2012年130-5]
- We recently reported that apoA-I and apoA-I mimetic peptides prevent the development of flank tumors in immunocompetent C57BL/6J mice. To delineate the mechanism(s) of action of apoA-I mimetic peptides in tumor developme...
- A distinct DNA methylation profile associated with microsatellite and chromosomal stable sporadic colorectal cancers
[作者:Silver, A; Sengupta, N; Propper, D; Wilson, P; Hagemann, T; Patel, A; Parker, A; Ghosh, A; Feakins, R; Dorudi, S; Suraweera, N,期刊:International Journal of Cancer, 页码:1082-1092 , 文章类型: Article,,卷期:2012年130-5]
- Aberrant DNA methylation, microsatellite instability (MSI) and chromosomal instability (CIN) are well-characterised molecular features of sporadic colorectal cancers (CRCs). In addition to CpG island methylator phenotype...
- Potentially functional polymorphisms in IL-23 receptor and risk of esophageal cancer in a Chinese population
[作者:Chu, HJ; Cao, WK; Chen, W; Pan, SD; Xiao, Y; Liu, Y; Gu, HY; Guo, W; Xu, L; Hu, ZB; Shen, H,期刊:International Journal of Cancer, 页码:1093-1097 , 文章类型: Article,,卷期:2012年130-5]
- Interleukin-23 (IL-23)/IL-23 receptor (IL-23R) is essential for Th17 cell-mediated immune response, involved in autoimmune diseases and cancer pathogenesis. Two potentially functional genetic single nucleotide polymorphi...
- Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization
[作者:Vandewoestyne, M; Kumps, C; Swerts, K; Menten, B; Lammens, T; Philippe, J; De Preter, K; Laureys, G; Van Roy, N; Speleman, F; Deforce, D,期刊:International Journal of Cancer, 页码:1098-1108 , 文章类型: Article,,卷期:2012年130-5]
- In neuroblastoma, tumor biopsies are used for prognostic evaluation and risk assessment by molecular genetic analyses such as fluorescence in situ hybridization (FISH) and array comparative genomic hybridization (array C...
- Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer
[作者:Eruslanov, E; Neuberger, M; Daurkin, I; Perrin, GQ; Algood, C; Dahm, P; Rosser, C; Vieweg, J; Gilbert, SM; Kusmartsev, S,期刊:International Journal of Cancer, 页码:1109-1119 , 文章类型: Article,,卷期:2012年130-5]
- Both cancer-related inflammation and tumor-induced immune suppression are associated with expansion of myeloid cell subsets including myeloid-derived suppressor cells. However, little known regarding characteristics of m...
- Nuclear HER3 is associated with favorable overall survival in uveal melanoma
[作者:Trocme, E; Mougiakakos, D; Johansson, CC; All-Eriksson, C; Economou, MA; Larsson, O; Seregard, S; Kiessling, R; Lin, YB,期刊:International Journal of Cancer, 页码:1120-1127 , 文章类型: Article,,卷期:2012年130-5]
- HER3 is a member of the epidermal growth factor receptor (EGFR) family and is expressed in several types of cancer. Both the cytoplasmic and nuclear appearances of the receptor have been reported. Here, we investigate th...
- Experience with high-risk human papillomavirus testing on vaginal brush-based self-samples of non-attendees of the cervical screening program
[作者:Gok, M; van Kemenade, FJ; Heideman, DAM; Berkhof, J; Rozendaal, L; Spruyt, JWM; Belien, JAM; Babovic, M; Snijders, PJF; Meijer, CJLM,期刊:International Journal of Cancer, 页码:1128-1135 , 文章类型: Article,,卷期:2012年130-5]
- We evaluated the effect of offering brush-based vaginal self-sampling for high-risk human papillomavirus (hrHPV) testing to non-attendees of the cervical screening program on response rate, compliance to follow-up and ce...
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