- The virtual element in proximal promoter of porcine myostatin is regulated by myocyte enhancer factor 2C
[作者:Li, J; Deng, J; Yu, S; Zhang, JL; Cheng, D; Wang, HY,期刊:Biochemical and Biophysical Research Communications, 页码:175-181 , 文章类型: Article,,卷期:2012年419-2]
- Myostatin (myostatin) is a member of the transforming growth factor-beta superfamily. In this study, we investigated the transcriptional regulation of porcine myostatin expression in C2C12 cells. Sequence analysis of 2 k...
- Bioluminescent system for dynamic imaging of cell and animal behavior
[作者:Hara-Miyauchi, C; Tsuji, O; Hanyu, A; Okada, S; Yasuda, A; Fukano, T; Akazawa, C; Nakamura, M; Imamura, T; Matsuzaki, Y; Okano, HJ; Miyawaki, A; Okano, H,期刊:Biochemical and Biophysical Research Communications, 页码:188-193 , 文章类型: Article,,卷期:2012年419-2]
- The current utility of bioluminescence imaging is constrained by a low photon yield that limits temporal sensitivity. Here, we describe an imaging method that uses a chemiluminescent/fluorescent protein, ffLuc-cp156, whi...
- Formation of low-dimensional crystalline nucleus region during insulin amyloidogenesis process
[作者:Amdursky, N; Gazit, E; Rosenman, G,期刊:Biochemical and Biophysical Research Communications, 页码:232-237 , 文章类型: Article,,卷期:2012年419-2]
- Insulin, as other amyloid proteins, can form amyloid fibrils at certain conditions. The self-assembled aggregation process of insulin can result in a variety of conformations, starting from small oligomers, going through...
- Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro
[作者:Mizutani, T; Nakamura, T; Morikawa, R; Fukuda, M; Mochizuki, W; Yamauchi, Y; Nozaki, K; Yui, S; Nemoto, Y; Nagaishi, T; Okamoto, R; Tsuchiya, K; Watanabe, M,期刊:Biochemical and Biophysical Research Communications, 页码:238-243 , 文章类型: Article,,卷期:2012年419-2]
- P-glycoprotein (P-gp) is an efflux transporter that regulates bioavailability of orally administered drugs at the intestinal epithelium. To develop an in vitro experimental model that mimics P-gp-mediated intestinal drug...
- Fructose induces tubulointerstitial injury in the kidney of mice
[作者:Aoyama, M; Isshiki, K; Kume, S; Chin-Kanasaki, M; Araki, H; Araki, S; Koya, D; Haneda, M; Kashiwagi, A; Maegawa, H; Uzu, T,期刊:Biochemical and Biophysical Research Communications, 页码:244-249 , 文章类型: Article,,卷期:2012年419-2]
- Fructose induces several kinds of human metabolic disorders; however, information regarding fructose-induced kidney injury is still limited. This study examined fructose-induced kidney injury in mice and clarified the di...
- Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-kappa B signaling pathway
[作者:Soromou, LW; Chen, N; Jiang, LN; Huo, MX; Wei, MM; Chu, X; Millimouno, FM; Feng, HH; Sidime, Y; Deng, XM,期刊:Biochemical and Biophysical Research Communications, 页码:256-261 , 文章类型: Article,,卷期:2012年419-2]
- Astragalin (AG), a flavonoid from many traditional herbs and medicinal plants, has been described to exhibit in vitro anti-inflammatory activity. The present study aimed to determine the protective effects and the underl...
- Overexpression of alpha CP2, a translational repressor of GAP-43, inhibited axon outgrowth during development in Xenopus laevis
[作者:Wang, J; Sun, SG; Cao, XB; Deng, XJ; Zhang, YJ; Zhu, Q,期刊:Biochemical and Biophysical Research Communications, 页码:262-267 , 文章类型: Article,,卷期:2012年419-2]
- The 3'-untranslated regions (3'-UTRs) of growth-associated protein 43 (GAP-43), which is crucial for neural development and axonal regeneration, are highly conserved among vertebrates. Previous studies in mammals have id...
- Involvement of CNOT3 in mitotic progression through inhibition of MAD1 expression
[作者:Takahashi, A; Kikuguchi, C; Morita, M; Shimodaira, T; Tokai-Nishizumi, N; Yokoyama, K; Ohsugi, M; Suzuki, T; Yamamoto, T,期刊:Biochemical and Biophysical Research Communications, 页码:268-273 , 文章类型: Article,,卷期:2012年419-2]
- The stability of mRNA influences the dynamics of gene expression. The CCR4-NOT complex, the major deadenylase in mammalian cells, shortens the mRNA poly(A) tail and contributes to the destabilization of mRNAs. The CCR4-N...
- Human epididymis protein 4 (HE4) plays a key role in ovarian cancer cell adhesion and motility
[作者:Lu, RQ; Sun, XH; Xiao, R; Zhou, L; Gao, X; Guo, L,期刊:Biochemical and Biophysical Research Communications, 页码:274-280 , 文章类型: Article,,卷期:2012年419-2]
- Human epididymis protein 4 (HE4) is a novel and specific biomarker for epithelial ovarian cancer (EOC). We previously demonstrated that serum HE4 levels were significantly elevated in the majority of EOC patients but not...
- Tie1 regulates the Tie2 agonistic role of angiopoietin-2 in human lymphatic endothelial cells
[作者:Song, SH; Kim, KL; Lee, KA; Suh, W,期刊:Biochemical and Biophysical Research Communications, 页码:281-286 , 文章类型: Article,,卷期:2012年419-2]
- Although Angiopoietin (Ang) 2 has been shown to function as a Tie2 antagonist in vascular endothelial cells, several recent studies on Ang2-deficient mice have reported that, like Angl, Ang2 acts as a Tie2 agonist during...
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