- Suppression of phospholipase C gamma 1 phosphorylation by cinnamaldehyde inhibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells
[作者:Kageyama-Yahara, N; Wang, XY; Katagiri, T; Wang, P; Yamamoto, T; Tominaga, M; Kadowaki, M,期刊:Biochemical and Biophysical Research Communications, 页码:283-288 , 文章类型: Article,,卷期:2011年416-3-4]
- Antigen-IgE-mediated mucosal mast-cell activation is critical in the development of food allergies. Cinnamaldehyde, a major constituent of Cinnamomi cortex, dose-dependently inhibited the antigen-IgE-induced degranulatio...
- Transgenic overexpression of bone morphogenetic protein 11 propeptide in skeleton enhances bone formation
[作者:Li, ZC; Zeng, F; Mitchell, AD; Kim, YS; Wu, ZF; Yang, JZ,期刊:Biochemical and Biophysical Research Communications, 页码:289-292 , 文章类型: Article,,卷期:2011年416-3-4]
- Bone morphogenetic protein 11 (BMP11) is a key regulatory protein in skeletal development. BMP11 propeptide has been shown to antagonize GDF11 activity in vitro. To explore the role of BMP11 propeptide in skeletal format...
- Increased cardiogenesis in P19-GFP teratocarcinoma cells expressing the propeptide IGF-1Ea
[作者:Poudel, B; Bilbao, D; Sarathchandra, P; Germack, R; Rosenthal, N; Santini, MP,期刊:Biochemical and Biophysical Research Communications, 页码:293-299 , 文章类型: Article,,卷期:2011年416-3-4]
- The mechanism implicated in differentiation of endogenous cardiac stem cells into cardiomyocytes to regenerate the heart tissue upon an insult remains elusive, limiting the therapeutical goals to exogenous cell injection...
- Ubiquitination of Notch1 is regulated by MAML1-mediated p300 acetylation of Notch1
[作者:Popko-Scibor, AE; Lindberg, MJ; Hansson, ML; Holmlund, T; Wallberg, AE,期刊:Biochemical and Biophysical Research Communications, 页码:300-306 , 文章类型: Article,,卷期:2011年416-3-4]
- Earlier studies demonstrated the involvement of the p300 histone acetyltransferase in Notch signaling but the precise mechanisms by which p300 might modulate Notch function remains to be investigated. In this study, we s...
- Inverse correlation between metallothioneins and hypoxia-inducible factor 1 alpha in colonocytes and experimental colitis
[作者:Devisscher, L; Hindryckx, P; Olievier, K; Peeters, H; De Vos, M; Laukens, D,期刊:Biochemical and Biophysical Research Communications, 页码:307-312 , 文章类型: Article,,卷期:2011年416-3-4]
- A positive-feedback mechanism between hypoxia-inducible factor 1 alpha (HIF-1 alpha) and metallothioneins (MTs) has been identified in different diseases. Both proteins have been independently proposed in the pathogenesi...
- The lectin ArtinM binds to mast cells inducing cell activation and mediator release
[作者:Barbosa-Lorenzi, VC; Buranello, PAD; Roque-Barreira, MC; Jamur, MC; Oliver, C; Pereira-da-Silva, G,期刊:Biochemical and Biophysical Research Communications, 页码:318-324 , 文章类型: Article,,卷期:2011年416-3-4]
- Mast cells are inflammatory cells that respond to signals of innate and adaptive immunity with immediate and delayed release of mediators. ArtinM, a lectin from Artocarpus integrifolia with immunomodulatory activities, i...
- Thyroid-specific gene expression in chondrocytes
[作者:Endo, T; Kobayashi, T,期刊:Biochemical and Biophysical Research Communications, 页码:227-231 , 文章类型: Article,,卷期:2011年416-3-4]
- Previously, we demonstrated that Runx2 (Cbfa1/AML3), a chondrocyte-specific transcription factor, is expressed in thyroid glands of mice, where it stimulates expression of the thyroglobulin (Tg) gene. Here, we reverse tr...
- STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH(+)/CD133(+) stem cell-like human colon cancer cells
[作者:Lin, L; Fuchs, J; Li, CL; Olson, V; Bekaii-Saab, T; Lin, JY,期刊:Biochemical and Biophysical Research Communications, 页码:246-251 , 文章类型: Article,,卷期:2011年416-3-4]
- Persistent activation of Signal Transducers and Activators of Transcription 3 (STAT3) is frequently detected in colon cancer. Increasing evidence suggests the existence of a small population of colon cancer stem or cance...
- Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism
[作者:Fedorova, OA; Moiseeva, TN; Nikiforov, AA; Tsimokha, AS; Livinskaya, VA; Hodson, M; Bottrill, A; Evteeva, IN; Ermolayeva, JB; Kuznetzova, IM; Turoverov, KK; Eperon, I; Barlev, NA,期刊:Biochemical and Biophysical Research Communications, 页码:258-265 , 文章类型: Article,,卷期:2011年416-3-4]
- The 26S proteasome is a large multi-subunit protein complex that exerts specific degradation of proteins in the cell. The 26S proteasome consists of the 20S proteolytic particle and the 19S regulator. In order to be targ...
- Effects of a human plasma membrane-associated sialidase siRNA on prostate cancer invasion
[作者:Li, XJ; Zhang, L; Shao, YT; Liang, ZW; Shao, C; Wang, B; Guo, BF; Li, N; Zhao, XJ; Li, Y; Xu, DQ,期刊:Biochemical and Biophysical Research Communications, 页码:270-276 , 文章类型: Article,,卷期:2011年416-3-4]
- Human plasma membrane-associated sialidase (Neu3) is one of several sialidases that hydrolyze sialic acids in the terminal position of the carbohydrate groups of glycolipids and glycoproteins. Neu3 is mainly localized in...
- Expression and characterization of recombinant kurtoxin, an inhibitor of T-type voltage-gated calcium channels
[作者:Lee, CW; Eu, YJ; Min, HJ; Cho, EM; Lee, JH; Kim, HH; Nah, SY; Swartz, KJ; Kim, JI,期刊:Biochemical and Biophysical Research Communications, 页码:277-282 , 文章类型: Article,,卷期:2011年416-3-4]
- Kurtoxin, a 63-amino acid peptide stabilized by four disulfide bonds, is the first reported peptide inhibitor of T-type voltage-gated calcium channels. Although T-type calcium channels have been implicated in a number of...
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