- Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension
[作者：Launay, JM; Herve, P; Callebert, J; Mallat, Z; Collet, C; Doly, S; Belmer, A; Diaz, SL; Hatia, S; Cote, F; Humbert, M; Maroteaux, L,期刊：Blood, 页码：1772-1780 , 文章类型： Article，,卷期：2012年119-7]
- Pulmonary arterial hypertension (PAH) is a progressive disease characterized by lung endothelial dysfunction and vascular remodeling. Recently, bone marrow progenitor cells have been localized to PAH lungs, raising the q...
- Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization
[作者：Brozzo, MS; Bjelic, S; Kisko, K; Schleier, T; Leppanen, VM; Alitalo, K; Winkler, FK; Ballmer-Hofer, K,期刊：Blood, 页码：1781-1788 , 文章类型： Article，,卷期：2012年119-7]
- VEGFs activate 3 receptor tyrosine kinases, VEGFR-1, VEGFR-2, and VEGFR-3, promoting angiogenic and lymphangiogenic signaling. The extracellular receptor domain (ECD) consists of 7 Ig-homology domains; domains 2 and 3 (D...
- The FLT3 and Pim kinases inhibitor SGI-1776 preferentially target FLT3-ITD AML cells
[作者：Hospital, MA; Green, AS; Lacombe, C; Mayeux, P; Bouscary, D; Tamburini, J,期刊：Blood, 页码：1791-1792 , 文章类型： Letter，,卷期：2012年119-7]
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- e-Blood Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cells
[作者：Hwang, KK; Chen, X; Kozink, DM; Gustilo, M; Marshall, DJ; Whitesides, JF; Liao, HX; Catera, R; Chu, CC; Yan, XJ; Luftig, MA; Haynes, BF; Chiorazzi, N,期刊：Blood, 页码：E35-E44 , 文章类型： Article，,卷期：2012年119-7]
- B-cell chronic lymphocytic leukemia (B-CLL) is characterized by the clonal expansion of CD5-expressing B lymphocytes that produce mAbs often reactive with microbial or autoantigens. Long-term culture of B-CLL clones woul...
- Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs
[作者：Van den Bossche, J; Malissen, B; Mantovani, A; De Baetselier, P; Van Ginderachter, JA,期刊：Blood, 页码：1623-1633 , 文章类型： Review，,卷期：2012年119-7]
- E-cadherin is best characterized as adherens junction protein, which through homotypic interactions contributes to the maintenance of the epithelial barrier function. In epithelial cells, the cytoplasmic tail of E-cadher...
- Model systems of genetically modified platelets
[作者：Thijs, T; Deckmyn, H; Broos, K,期刊：Blood, 页码：1634-1642 , 文章类型： Review，,卷期：2012年119-7]
- Although platelets are the smallest cells in the blood, they are implied in various processes ranging from immunology and oncology to thrombosis and hemostasis. Many large-scale screening programs, genome-wide associatio...
- Prognostic factors in transformed mycosis fungoides: a retrospective analysis of 100 cases
[作者：Benner, MF; Jansen, PM; Vermeer, MH; Willemze, R,期刊：Blood, 页码：1643-1649 , 文章类型： Article，,卷期：2012年119-7]
- Large cell transformation (LCT) in mycosis fungoides (MF) is generally associated with an aggressive clinical course and poor survival, requiring aggressive therapeutic approach. However, a proportion of cases may follow...
- Morbidity and mortality in common variable immune deficiency over 4 decades
[作者：Resnick, ES; Moshier, EL; Godbold, JH; Cunningham-Rundles, C,期刊：Blood, 页码：1650-1657 , 文章类型： Article，,卷期：2012年119-7]
- The demographics, immunologic parameters, medical complications, and mortality statistics from 473 subjects with common variable immune deficiency followed over 4 decades in New York were analyzed. Median immunoglobulin ...
- Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia
[作者：Kawedia, JD; Liu, CC; Pei, DQ; Cheng, C; Fernandez, CA; Howard, SC; Campana, D; Panetta, JC; Bowman, WP; Evans, WE; Pui, CH; Relling, MV,期刊：Blood, 页码：1658-1664 , 文章类型： Article，,卷期：2012年119-7]
- We have previously hypothesized that higher systemic exposure to asparaginase may cause increased exposure to dexamethasone, both critical chemotherapeutic agents for acute lymphoblastic leukemia. Whether interpatient ph...
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