- HIV Monoinfection Is Associated With Increased Aspartate Aminotransferase-to-Platelet Ratio Index, a Surrogate Marker for Hepatic Fibrosis
[作者:Price, JC; Seaberg, EC; Badri, S; Witt, MD; D'Acunto, K; Thio, CL,期刊:Journal of Infectious Diseases, 页码:1005-1013 , 文章类型: Article,,卷期:2012年205-6]
- Background. Although liver disease commonly causes morbidity and mortality among human immunodeficiency virus (HIV)-infected individuals, data are limited on its prevalence in HIV monoinfection. We used the aspartate ami...
- HIV-1 DNA Is Detected in Bone Marrow Populations Containing CD4(+) T Cells but Is not Found in Purified CD34(+) Hematopoietic Progenitor Cells in Most Patients on Antiretroviral Therapy
[作者:Durand, CM; Ghiaur, G; Siliciano, JD; Rabi, SA; Eisele, EE; Salgado, M; Shan, L; Lai, JF; Zhang, H; Margolick, J; Jones, RJ; Gallant, JE; Ambinder, RF; Siliciano, RF,期刊:Journal of Infectious Diseases, 页码:1014-1018 , 文章类型: Article,,卷期:2012年205-6]
- Identifying cellular reservoirs of human immunodeficiency virus type 1 (HIV-1) in patients on antiretroviral therapy (ART) is critical to finding a cure for HIV-1. In addition to resting CD4(+) T cells, CD34(+) hematopoi...
- Impaired Fitness of Mycobacterium africanum Despite Secretion of ESAT-6
[作者:Bold, TD; Davis, DC; Penberthy, KK; Cox, LM; Ernst, JD; de Jong, BC,期刊:Journal of Infectious Diseases, 页码:984-990 , 文章类型: Article,,卷期:2012年205-6]
- Background. When compared with Mycobacterium tuberculosis, individuals that live in the same household as an active case of smear-positive pulmonary tuberculosis exposed to M. africanum progress less frequently to active...
- Infection With Cryptosporidium hominis Provides Incomplete Protection of the Host Against Cryptosporidium parvum
[作者:Sheoran, A; Wiffin, A; Widmer, G; Singh, P; Tzipori, S,期刊:Journal of Infectious Diseases, 页码:1019-1023 , 文章类型: Article,,卷期:2012年205-6]
- Cryptosporidium hominis and Cryptosporidium parvum, which infect humans equally, are genetically/antigenically almost identical. It remains unclear, however, whether infection with C. hominis protects against C. parvum. ...
- Sensitive Detection Assays for Influenza RNA Do Not Reveal Viremia in US Blood Donors
[作者:Stramer, SL; Collins, C; Nugent, T; Wang, X; Fuschino, M; Heitman, JW; Law, J; Krysztof, DE; Kiely, N; Todd, D; Vermeulen, NMJ; Harrington, K; Kamel, H; Kelvin, DJ; Busch, MP; George, KS; Hewlett, IK; Linnen, JM; Norris, PJ,期刊:Journal of Infectious Diseases, 页码:886-894 , 文章类型: Article,,卷期:2012年205-6]
- Background. There have been anecdotal reports of influenza viremia since the 1960s. We present an assessment of the prevalence of seasonal and 2009 H1N1 influenza viremia (via RNA testing) in blood donor populations usin...
- Early Age at Time of Primary Epstein-Barr Virus Infection Results in Poorly Controlled Viral Infection in Infants From Western Kenya: Clues to the Etiology of Endemic Burkitt Lymphoma
[作者:Piriou, E; Asito, AS; Sumba, PO; Fiore, N; Middeldorp, JM; Moormann, AM; Ploutz-Snyder, R; Rochford, R,期刊:Journal of Infectious Diseases, 页码:906-913 , 文章类型: Article,,卷期:2012年205-6]
- Background. Infection with Epstein-Barr virus (EBV) early in life and repeated malaria exposure have been proposed as risk factors for endemic Burkitt lymphoma (eBL). Methods. Infants were enrolled from 2 rural sites in ...
- Leptospiral Immunoglobulin-like Proteins Interact With Human Complement Regulators Factor H, FHL-1, FHR-1, and C4BP
[作者:Castiblanco-Valencia, MM; Fraga, TR; da Silva, LB; Monaris, D; Abreu, PAE; Strobel, S; Jozsi, M; Isaac, L; Barbosa, AS,期刊:Journal of Infectious Diseases, 页码:995-1004 , 文章类型: Article,,卷期:2012年205-6]
- Leptospira, the causative agent of leptospirosis, interacts with several host molecules, including extracellular matrix components, coagulation cascade proteins, and human complement regulators. Here we demonstrate that ...
- Species-Specific Recognition of Aspergillus fumigatus by Toll-like Receptor 1 and Toll-like Receptor 6
[作者:Rubino, I; Coste, A; Le Roy, D; Roger, T; Jaton, K; Boeckh, M; Monod, M; Latge, JP; Calandra, T; Bochud, PY,期刊:Journal of Infectious Diseases, 页码:944-954 , 文章类型: Article,,卷期:2012年205-6]
- Background. Aspergillus fumigatus causes invasive aspergillosis, a potentially fatal infection in oncohematological patients. Innate immune detection of A. fumigatus involves Toll-like receptor (TLR) 4 and TLR2, which fo...
- Epidemiologic Consequences of Microvariation in Mycobacterium tuberculosis
[作者:Mathema, B; Kurepina, N; Yang, GB; Shashkina, E; Manca, C; Mehaffy, C; Bielefeldt-Ohmann, H; Ahuja, S; Fallows, DA; Izzo, A; Bifani, P; Dobos, K; Kaplan, G; Kreiswirth, BN,期刊:Journal of Infectious Diseases, 页码:964-974 , 文章类型: Article,,卷期:2012年205-6]
- Background. Evidence from genotype-phenotype studies suggests that genetic diversity in pathogens have clinically relevant manifestations that can impact outcome of infection and epidemiologic success. We studied 5 close...
- The Identification of Gene Duplication and the Role of Secreted Aspartyl Proteinase 1 in Candida parapsilosis Virulence
[作者:Horvath, P; Nosanchuk, JD; Hamari, Z; Vagvolgyi, C; Gacser, A,期刊:Journal of Infectious Diseases, 页码:923-933 , 文章类型: Article,,卷期:2012年205-6]
- In this study, we analyzed the role of Candida parapsilosis-secreted aspartyl proteinase isoenzyme 1 (SAPP1) in virulence. The in silico analysis of SAPP1 sequence revealed a 2871 base pair-duplicated region (SAPP1a and ...
- Failure of Topical Antibiotics to Prevent Disseminated Borrelia burgdorferi Infection Following a Tick Bite in C3H/HeJ Mice
[作者:Wormser, GP; Daniels, TJ; Bittker, S; Cooper, D; Wang, GQ; Pavia, CS,期刊:Journal of Infectious Diseases, 页码:991-994 , 文章类型: Article,,卷期:2012年205-6]
- A prior study in mice has shown that the timely application of topical antibiotics to the skin at the tick bite site could eradicate Borrelia burgdorferi infection. That study, however, did not evaluate antibiotic prepar...
- Myocardial Injury and Bacterial Pneumonia Contribute to the Pathogenesis of Fatal Influenza B Virus Infection
[作者:Paddock, CD; Liu, L; Denison, AM; Bartlett, JH; Holman, RC; DeLeon-Carnes, M; Emery, SL; Drew, CP; Shieh, WJ; Uyeki, TM; Zaki, SR,期刊:Journal of Infectious Diseases, 页码:895-905 , 文章类型: Article,,卷期:2012年205-6]
- Background. Influenza B virus infection causes rates of hospitalization and influenza-associated pneumonia similar to seasonal influenza A virus infection and accounts for a substantial percentage of all influenza-relate...
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