- Thermal Stability of Fibroblast Growth Factor Protein Is a Determinant Factor in Regulating Self-Renewal, Differentiation, and Reprogramming in Human Pluripotent Stem Cells
[作者：Chen, G; Gulbranson, DR; Yu, PZ; Hou, ZG; Thomson, JA,期刊：Stem Cells, 页码：623-630 , 文章类型： Article，,卷期：2012年30-4]
- Fibroblast growth factor (FGF), transforming growth factor (TGF)/Nodal, and Insulin/insulin-like growth factor (IGF) signaling pathways are sufficient to maintain human embryonic stem cells (ESCs) and induced pluripotent...
- Activin and BMP4 Synergistically Promote Formation of Definitive Endoderm in Human Embryonic Stem Cells
[作者：Teo, AKK; Ali, Y; Wong, KY; Chipperfield, H; Sadasivam, A; Poobalan, Y; Tan, EK; Wang, ST; Abraham, S; Tsuneyoshi, N; Stanton, LW; Dunn, NR,期刊：Stem Cells, 页码：631-642 , 文章类型： Article，,卷期：2012年30-4]
- Human embryonic stem cells (hESCs) herald tremendous promise for the production of clinically useful cell types for the treatment of injury and disease. Numerous reports demonstrate their differentiation into definitive ...
- Role of MicroRNAs 99b, 181a, and 181b in the Differentiation of Human Embryonic Stem Cells to Vascular Endothelial Cells
[作者：Kane, NM; Howard, L; Descamps, B; Meloni, M; McClure, J; Lu, RF; McCahill, A; Breen, C; Mackenzie, RM; Delles, C; Mountford, JC; Milligan, G; Emanueli, C; Baker, AH,期刊：Stem Cells, 页码：643-654 , 文章类型： Article，,卷期：2012年30-4]
- MicroRNAs (miRNAs) are short noncoding RNAs, which post-transcriptionally regulate gene expression. miRNAs are transcribed as precursors and matured to active forms by a series of enzymes, including Dicer. miRNAs are imp...
- The Novel Function of OCT4B Isoform-265 in Genotoxic Stress
[作者：Gao, Y; Wei, JS; Han, J; Wang, X; Su, GN; Zhao, YN; Chen, B; Xiao, ZF; Cao, JN; Dai, JW,期刊：Stem Cells, 页码：665-672 , 文章类型： Article，,卷期：2012年30-4]
- OCT4 is a key transcription factor in maintaining the pluripotency and self-renewal of embryonic stem cells (ESCs). Human OCT4 gene can generate three mRNA isoforms (OCT4A, OCT4B, and OCT4B1) by alternative splicing and ...
- PKA/CREB Signaling Triggers Initiation of Endothelial and Hematopoietic Cell Differentiation via Etv2 Induction
[作者：Yamamizu, K; Matsunaga, T; Katayama, S; Kataoka, H; Takayama, N; Eto, K; Nishikawa, S; Yamashita, JK,期刊：Stem Cells, 页码：687-696 , 文章类型： Article，,卷期：2012年30-4]
- Ets family protein Etv2 (also called ER71 or Etsrp) is a key factor for initiation of vascular and blood development from mesodermal cells. However, regulatory mechanisms and inducing signals for Etv2 expression have bee...
- Novel Pathways to Erythropoiesis Induced by Dimerization of Intracellular C-Mpl in Human Hematopoietic Progenitors
[作者：Parekh, C; Sahaghian, A; Kim, W; Scholes, J; Ge, SD; Zhu, YH; Asgharzadeh, S; Hollis, R; Kohn, D; Ji, LY; Malvar, J; Wang, XY; Crooks, G,期刊：Stem Cells, 页码：697-708 , 文章类型： Article，,卷期：2012年30-4]
- The cytokine thrombopoietin (Tpo) plays a critical role in hematopoiesis by binding to the extracellular domain and inducing homodimerization of the intracellular signaling domain of its receptor, c-Mpl. Mpl homodimeriza...
- Noncanonical NF-?B Signaling Regulates Hematopoietic Stem Cell Self-Renewal and Microenvironment Interactions
[作者：Zhao, C; Xiu, Y; Ashton, J; Xing, LP; Morita, Y; Jordan, CT; Boyce, BF,期刊：Stem Cells, 页码：709-718 , 文章类型： Article，,卷期：2012年30-4]
- RelB and nuclear factor ?B (NF-?B2) are the main effectors of NF-?B noncanonical signaling and play critical roles in many physiological processes. However, their role in hematopoietic stem/progenitor cell (HSPC) mainten...
- An Endogenous Vitamin K-Dependent Mechanism Regulates Cell Proliferation in the Brain Subventricular Stem Cell Niche
[作者：Gely-Pernot, A; Coronas, V; Harnois, T; Prestoz, L; Mandairon, N; Didier, A; Berjeaud, JM; Monvoisin, A; Bourmeyster, N; De Frutos, PG; Philippe, M; Benzakour, O,期刊：Stem Cells, 页码：719-731 , 文章类型： Article，,卷期：2012年30-4]
- Neural stem cells (NSC) persist in the adult mammalian brain, within the subventricular zone (SVZ). The endogenous mechanisms underpinning SVZ stem and progenitor cell proliferation are not fully elucidated. Vitamin K-de...
- The In Vivo Response of Stem and Other Undifferentiated Spermatogonia to the Reversible Inhibition of Glial Cell Line-Derived Neurotrophic Factor Signaling in the Adult
[作者：Savitt, J; Singh, D; Zhang, C; Chen, LC; Folmer, J; Shokat, KM; Wright, WW,期刊：Stem Cells, 页码：732-740 , 文章类型： Article，,卷期：2012年30-4]
- Maintaining adequate numbers of spermatogonial stem cells is required for the production of the millions of sperm required for male fertility. To date, however, the mechanisms that regulate the size of this pool in the a...
- Genome-Wide Analysis of N1ICD/RBPJ Targets In Vivo Reveals Direct Transcriptional Regulation of Wnt, SHH, and Hippo Pathway Effectors by Notch1
[作者：Li, YC; Hibbs, MA; Gard, AL; Shylo, NA; Yun, KS,期刊：Stem Cells, 页码：741-752 , 文章类型： Article，,卷期：2012年30-4]
- The Notch pathway plays a pivotal role in regulating cell fate decisions in many stem cell systems. However, the full repertoire of Notch target genes in vivo and the mechanisms through which this pathway activity is int...
- Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem Cells
[作者：Lu, R; Qu, YLW; Ge, J; Zhang, LL; Su, ZT; Pflugfelder, SC; Li, DQ,期刊：Stem Cells, 页码：753-761 , 文章类型： Article，,卷期：2012年30-4]
- TCF4, a key transcription factor of Wnt signaling system, has been recently found to be essential for maintaining stem cells. However, its signaling pathway is not well elucidated. This study was to explore the functiona...
- Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling
[作者：Guihard, P; Danger, Y; Brounais, B; David, E; Brion, R; Delecrin, J; Richards, CD; Chevalier, S; Redini, F; Heymann, D; Gascan, H; Blanchard, F,期刊：Stem Cells, 页码：762-772 , 文章类型： Article，,卷期：2012年30-4]
- Bone resorption by osteoclasts and bone formation by osteoblasts are tightly coupled processes implicating factors in TNF, bone morphogenetic protein, and Wnt families. In osteoimmunology, macrophages were described as a...
- Histamine Stimulates Neurogenesis in the Rodent Subventricular Zone
[作者：Bernardino, L; Eiriz, MF; Santos, T; Xapelli, S; Grade, S; Rosa, AI; Cortes, L; Ferreira, R; Braganca, J; Agasse, F; Ferreira, L; Malva, JO,期刊：Stem Cells, 页码：773-784 , 文章类型： Article，,卷期：2012年30-4]
- Neural stem/progenitor cells present in the subventricular zone (SVZ) are a potential source of repairing cells after injury. Therefore, the identification of novel players that modulate neural stem cells differentiation...
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