- FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan-protein linkage region
[作者:Koike, T; Izumikawa, T; Tamura, JI; Kitagawa, H,期刊:Biochemical Journal, 页码:157-162 , 文章类型: Article,,卷期:2009年421-Part 2]
- 2-O-phosphorylation of xylose has been detected in the glycosaminoglycan-protein linkage region, GlcA beta 1-3Gal beta 1-3Gal beta 1-4Xyl beta 1-O-Ser, of proteoglycans. Recent Mutant analyses in zebrafish suggest that x...
- A cotton kinesin GhKCH2 interacts with both microtubules and microfilaments
[作者:Xu, T; Qu, Z; Yang, XY; Qin, XH; Xiong, JY; Wang, YQ; Ren, DT; Liu, GQ,期刊:Biochemical Journal, 页码:171-180 , 文章类型: Article,,卷期:2009年421-Part 2]
- Many biological processes require the co-operative involvement of both microtubules and microfilaments; however, only a few proteins mediating the interaction between microtubules and microfilaments have been identified ...
- Hsp70 is required for optimal cell proliferation in mouse A6 mesoangioblast stem cells
[作者:Turturici, G; Geraci, F; Candela, ME; Cossu, G; Giudice, G; Sconzo, G,期刊:Biochemical Journal, 页码:193-200 , 文章类型: Article,,卷期:2009年421-Part 2]
- Mouse Hsp70 (70 kDa heat shock protein) is preferentially induced by heat or stress stimuli. We previously found that Hsp70 is constitutively expressed in A6 Mouse mesoangioblast stem cells, but its possible role in thes...
- NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A(2)
[作者:Zhu, DH; Hu, CH; Sheng, WW; Tan, KS; Haidekker, MA; Sun, AY; Sun, GY; Lee, JCM,期刊:Biochemical Journal, 页码:201-210 , 文章类型: Article,,卷期:2009年421-Part 2]
- ROS (reactive oxygen species) overproduction is an important underlying factor for the activation of astrocytes in various neuropathological conditions. In the present Study, we examined ROS production in astrocytes and ...
- The carbohydrate-binding domain on galectin-1 is more extensive for a complex glycan than for simple saccharides: implications for galectin-glycan interactions at the cell surface
[作者:Miller, MC; Nesmelova, IV; Platt, D; Klyosov, A; Mayo, KH,期刊:Biochemical Journal, 页码:211-221 , 文章类型: Article,,卷期:2009年421-Part 2]
- gal-1 (galectin-1) mediates cell-cell and cell-extracellular matrix adhesion, essentially by interacting with beta-galactoside-containing glycans of cell-surface glycoconjugates. Although most structural studies with gal...
- Characterization of SENP7, a SUMO-2/3-specific isopeptidase
[作者:Shen, LN; Geoffroy, MC; Jaffray, EG; Hay, RT,期刊:Biochemical Journal, 页码:223-230 , 文章类型: Article,,卷期:2009年421-Part 2]
- The modification of proteins by SUMO (small ubiquitin-related modifier) plays important roles in regulating the activity, stability and cellular localization of target proteins. Similar to ubiquitination, SUMO modificati...
- Functional characterization of LePGT1, a membrane-bound prenyltransferase involved in the geranylation of p-hydroxybenzoic acid
[作者:Ohara, K; Muroya, A; Fijkushima, N; Yazaki, K,期刊:Biochemical Journal, 页码:231-241 , 文章类型: Article,,卷期:2009年421-Part 2]
- The AS-PT (aromatic substrate prenyltransferase) family plays a critical role in the biosynthesis of important quinone compounds such as ubiquinone and plastoquinone, although biochemical characterizations of AS-PTs have...
- NEMO oligomerization and its ubiquitin-binding properties
[作者:Ivins, FJ; Montgomery, MG; Smith, SJM; Morris-Davies, AC; Taylor, IA; Rittinger, K,期刊:Biochemical Journal, 页码:243-251 , 文章类型: Article,,卷期:2009年421-Part 2]
- The IKK [I kappa B (inhibitory kappa B) kinase] complex is a key regulatory component of NF-kappa B (nuclear factor kappa B) activation and is responsible for mediating the degradation of I kappa B, thereby allowing nucl...
- Pseudomonas aeruginosa MurE amide ligase: enzyme kinetics and peptide inhibitor
[作者:Paradis-Bleau, C; Lloyd, A; Sanschagrin, F; Maaroufi, H; Clarke, T; Blewett, A; Dowson, C; Roper, DI; Bugg, TDH; Levesque, RC,期刊:Biochemical Journal, 页码:263-272 , 文章类型: Article,,卷期:2009年421-Part 2]
- The enzyme kinetics of the amide ligase MurE, a cell wall biosynthesis enzyme, from Pseudomonas aeruginosa were determined using the synthesized nucleotide substrate UDP-MurNAc-Ala-Glu (uridine 5'-diphosphoryl N-acetylmu...
- The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways
[作者:Schiavone, D; Dewilde, S; Vallania, F; Turkson, J; Di Cunto, F; Poli, V,期刊:Biochemical Journal, 页码:283-292 , 文章类型: Article,,卷期:2009年421-Part 2]
- STAT3 (signal transducer and activator of transcription 3) is a transcription factor activated by cytokines, growth factors and oncogenes, whose activity is required for cell survival/proliferation of a wide variety of p...
- Dynamic aspects of ascorbic acid metabolism in the circulation: analysis by ascorbate oxidase with a prolonged in vivo half-life
[作者:Kasahara, E; Kashiba, M; Jikumaru, M; Kuratsune, D; Orita, K; Yamate, Y; Hara, K; Sekiyama, A; Sato, EF; Inoue, M,期刊:Biochemical Journal, 页码:293-299 , 文章类型: Article,,卷期:2009年421-Part 2]
- Because AA (L-ascorbic acid) scavenges various types of free radicals to form MDAA (monodehydroascorbic acid) and DAA (dehydroascorbic acid), its regeneration from the oxidized metabolites is critically important for hum...
- Nuclear factor kappa B (NF-kappa B) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist
[作者:Lee, J; Hayashi, M; Lo, JF; Fearns, C; Chu, WM; Luo, YP; Xiang, R; Chuang, TH,期刊:Biochemical Journal, 页码:301-310 , 文章类型: Article,,卷期:2009年421-Part 2]
- TLR7 (Toll-like receptor 7) mediates anti-viral immunity by recognizing ssRNA (single-stranded RNA) viruses. Small-molecular-mass TLR7 agonists have been approved, or are being evaluated, for treatment of cancers or infe...
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