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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共16条记录   Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19(ARF) expression [作者：Suzuki, A; Sekiya, S; Buscher, D; Belmonte, JCI; Taniguchi, H,期刊：Development, 页码：1589-1595 , 文章类型： Article，,卷期：2008年135-9] Although the T-box family of transcription factors function in many different tissues, their role in liver development is unknown. Here we show that Tbx3, the T-box gene that is mutated in human ulnar-mammary syndrome, i... Requirement for Foxd3 in the maintenance of neural crest progenitors [作者：Teng, L; Mundell, NA; Frist, AY; Wang, QH; Labosky, PA,期刊：Development, 页码：1615-1624 , 文章类型： Article，,卷期：2008年135-9] Understanding the molecular mechanisms of stem cell maintenance is crucial for the ultimate goal of manipulating stem cells for the treatment of disease. Foxd3 is required early in mouse embryogenesis; Foxd3(-/-) embryos... Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme [作者：Rajagopal, J; Carroll, TJ; Guseh, JS; Bores, SA; Blank, LJ; Anderson, WJ; Yu, J; Zhou, Q; McMahon, AP; Melton, DA,期刊：Development, 页码：1625-1634 , 文章类型： Article，,卷期：2008年135-9] The effects of Wnt7b on lung development were examined using a conditional Wnt7b-null mouse. Wnt7b-null lungs are markedly hypoplastic, yet display largely normal patterning and cell differentiation. In contrast to findi... Critical numbers of neural crest cells are required in the pathways from the neural tube to the foregut to ensure complete enteric nervous system formation [作者：Barlow, AJ; Wallace, AS; Thapar, N; Burns, AJ,期刊：Development, 页码：1681-1691 , 文章类型： Article，,卷期：2008年135-9] The enteric nervous system (ENS) is mainly derived from vagal neural crest cells (NCC) that arise at the level of somites 1-7. To understand how the size and composition of the NCC progenitor pool affects ENS development... Tbx2b is required for the development of the parapineal organ [作者：Snelson, CD; Santhakumar, K; Halpern, ME; Gamse, JT,期刊：Development, 页码：1693-1702 , 文章类型： Article，,卷期：2008年135-9] Structural differences between the left and right sides of the brain exist throughout the vertebrate lineage. By studying the zebrafish pineal complex, which exhibits notable asymmetries, both the genes and the cell move... Different autonomous myogenic cell populations revealed by ablation of Myf5-expressing cells during mouse embryogenesis [作者：Gensch, N; Borchardt, T; Schneider, A; Riethmacher, D; Braun, T,期刊：Development, 页码：1597-1604 , 文章类型： Article，,卷期：2008年135-9] The development of myogenic cells is mainly determined by expression of two myogenic factors, Myf5 and Myod1 (MyoD), which genetically compensate for each other during embryogenesis. Here, we demonstrate by conditional c... Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells [作者：Schwarz, Q; Vieira, JM; Howard, B; Eickholt, BJ; Ruhrberg, C,期刊：Development, 页码：1605-1613 , 文章类型： Article，,卷期：2008年135-9] Neuropilin (NRP) receptors and their class 3 semaphorin (SEMA3) ligands play well-established roles in axon guidance, with loss of NRP1, NRP2, SEMA3A or SEMA3F causing defasciculation and errors in growth cone guidance o... Cell type specificity of a diffusible inducer is determined by a GATA family transcription factor [作者：Keller, T; Thompson, CRL,期刊：Development, 页码：1635-1645 , 文章类型： Article，,卷期：2008年135-9] One poorly understood mechanism of developmental patterning involves the intermingled differentiation of different cell types that then sort out to generate pattern. Examples of this are known in nematodes and vertebrate... Live imaging of the Dictyostelium cell cycle reveals widespread S phase during development, a G2 bias in spore differentiation and a premitotic checkpoint [作者：Muramoto, T; Chubb, JR,期刊：Development, 页码：1647-1657 , 文章类型： Article，,卷期：2008年135-9] The regulation of the Dictyostelium cell cycle has remained ambiguous owing to difficulties in long-term imaging of motile cells and a lack of markers for defining cell cycle phases. There is controversy over whether cel... Dynamic regulation of the expression of neurotrophin receptors by Runx3 [作者：Nakamura, S; Senzaki, K; Yoshikawa, M; Nishimura, M; Inoue, KI; Ito, Y; Ozaki, S; Shiga, T,期刊：Development, 页码：1703-1711 , 文章类型： Article，,卷期：2008年135-9] Sensory neurons in the dorsal root ganglion (DRG) specifically project axons to central and peripheral targets according to their sensory modality. However, the molecular mechanisms that govern sensory neuron differentia... The mutation ROR2(W749X), linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome [作者：Raz, R; Stricker, S; Gazzerro, E; Clor, JL; Witte, F; Nistala, H; Zabski, S; Pereira, RC; Stadmeyer, L; Wang, X; Gowen, L; Sleeman, MW; Yancopoulos, GD; Canalis, E; Mundlos, S; Valenzuela, DM; Economides, AN,期刊：Development, 页码：1713-1723 , 文章类型： Article，,卷期：2008年135-9] Mutations in ROR2 result in a spectrum of genetic disorders in humans that are classified, depending on the nature of the mutation and the clinical phenotype, as either autosomal dominant brachydactyly type B (BDB, MIM 1... Smt3 is required for Drosophila melanogaster metamorphosis [作者：Talamillo, A; Sanchez, J; Cantera, R; Perez, C; Martin, D; Caminero, E; Barrio, R,期刊：Development, 页码：1659-1668 , 文章类型： Article，,卷期：2008年135-9] Sumoylation, the covalent attachment of the small ubiquitin-related modifier SUMO to target proteins, regulates different cellular processes, although its role in the control of development remains unclear. We studied th... The YPWM motif links Antennapedia to the basal transcriptional machinery [作者：Prince, F; Katsuyama, T; Oshima, Y; Plaza, S; Resendez-Perez, D; Berry, M; Kurata, S; Gehring, WJ,期刊：Development, 页码：1669-1679 , 文章类型： Article，,卷期：2008年135-9] HOX genes specify segment identity along the anteroposterior axis of the embryo. They code for transcription factors harbouring the highly conserved homeodomain and a YPWM motif, situated amino terminally to it. Despite ... Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes [作者：Trowe, MO; Maier, H; Schweizer, M; Kispert, A,期刊：Development, 页码：1725-1734 , 文章类型： Article，,卷期：2008年135-9] In the cochlea, fibrocytes play important physiological roles, including the maintenance of the ionic composition of the endolymph. Human deafness upon fibrocyte alterations witnesses their crucial role for hearing. We d... Stem cell researchers find their niche [作者：Dzierzak, E; Enver, T,期刊：Development, 页码：1569-1573 , 文章类型： Review，,卷期：2008年135-9] The EuroSTELLS Workshop 'Stem Cell Niches', organised by Anna Bigas, Ernest Arenas and Pasqualino Loi, took place in January 2008 in Barcelona, Spain. The goal of the conference was to promote scientific collaboration an... Neural stem cells: balancing self-renewal with differentiation [作者：Doe, CQ,期刊：Development, 页码：1575-1587 , 文章类型： Review，,卷期：2008年135-9] Stem cells are captivating because they have the potential to make multiple cell types yet maintain their undifferentiated state. Recent studies of Drosophila and mammalian neural stem cells have shed light on how stem c...