- The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity
[作者：Laue, K; Daujat, S; Crump, JG; Plaster, N; Roehl, HH; Kimmel, CB; Schneider, R; Hammerschmidt, M,期刊：Development, 页码：1935-1946 , 文章类型： Article，,卷期：2008年135-11]
- The Trithorax group (TrxG) is composed of diverse, evolutionary conserved proteins that form chromatin-associated complexes accounting for epigenetic transcriptional memory. However, the molecular mechanisms by which par...
- Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization
[作者：Shimada, M; Yanai, Y; Okazaki, T; Noma, N; Kawashima, I; Mori, T; Richards, JS,期刊：Development, 页码：2001-2011 , 文章类型： Article，,卷期：2008年135-11]
- The toll-like receptor (TLR) system is expressed in cumulus cells of ovulated cumulus-oocyte complexes (COCs) and is activated by bacterial lipopolysaccharides (LPS). However, the endogenous ligand(s) for the TLRs and th...
- The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability
[作者：Dohmann, EMN; Levesque, MP; De Veylder, L; Reichardt, I; Juergens, G; Schmid, M; Schwechheimer, C,期刊：Development, 页码：2013-2022 , 文章类型： Article，,卷期：2008年135-11]
- The COP9 signalosome (CSN) is required for the full activity of cullin-RING E3 ubiquitin ligases (CRLs) in eukaryotes. CSN exerts its function on CRLs by removing the ubiquitin-related NEDD8 conjugate from the cullin sub...
- FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos
[作者：Ueno, H; Nakajo, N; Watanabe, M; Isoda, M; Sagata, N,期刊：Development, 页码：2023-2030 , 文章类型： Article，,卷期：2008年135-11]
- In vertebrate embryogenesis, neural induction is the earliest step through which the fate of embryonic ectoderm to neuroectoderm becomes determined. Cells in the neuroectoderm or neural precursors actively proliferate be...
- Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning
[作者：Liu, Y; Padgett, D; Takahashi, M; Li, H; Sayeed, A; Teichert, RW; Olivera, BM; McArdle, JJ; Green, WN; Lin, W,期刊：Development, 页码：1957-1967 , 文章类型： Article，,卷期：2008年135-11]
- Formation of the vertebrate neuromuscular junction (NMJ) takes place in a stereotypic pattern in which nerves terminate at select sarcolemmal sites often localized to the central region of the muscle fibers. Several line...
- PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila
[作者：Benoit, P; Papin, C; Kwak, JE; Wickens, M; Simonelig, M,期刊：Development, 页码：1969-1979 , 文章类型： Article，,卷期：2008年135-11]
- Cytoplasmic polyadenylation has an essential role in activating maternal mRNA translation during early development. In vertebrates, the reaction requires CPEB, an RNA-binding protein and the poly(A) polymerase GLD-2. GLD...
- ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells
[作者：Pan, L; Deng, M; Xie, XL; Gan, L,期刊：Development, 页码：1981-1990 , 文章类型： Article，,卷期：2008年135-11]
- LIM-homeodomain (HD) and POU-HD transcription factors play crucial roles in neurogenesis. However, it remains largely unknown how they cooperate in this process and what downstream target genes they regulate. Here, we sh...
- The TTG1-bHLH-MYB complex controls trichome cell fate and patterning through direct targeting of regulatory loci
[作者：Zhao, M; Morohashi, K; Hatlestad, G; Grotewold, E; Lloyd, A,期刊：Development, 页码：1991-1999 , 文章类型： Article，,卷期：2008年135-11]
- A network of three classes of proteins consisting of bHLH and MYB transcription factors, and a WD40 repeat protein, TRANSPARENT TESTA GLABRA1 (TTG1), act in concert to activate trichome initiation and patterning. Using Y...
- Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscle
[作者：Conti, FJ; Felder, A; Monkley, S; Schwander, M; Wood, MR; Lieber, R; Critchley, D; Mueller, U,期刊：Development, 页码：2043-2053 , 文章类型： Article，,卷期：2008年135-11]
- The development and function of skeletal muscle depend on molecules that connect the muscle fiber cytoskeleton to the extracellular matrix (ECM). beta 1 integrins are ECM receptors in skeletal muscle, and mutations that ...
- Post-meiotic transcription in Drosophila testes
[作者：Barreau, C; Benson, E; Gudmannsdottir, E; Newton, F; White-Cooper, H,期刊：Development, 页码：1897-1902 , 文章类型： Article，,卷期：2008年135-11]
- Post-meiotic transcription was accepted to be essentially absent from Drosophila spermatogenesis. We identify 24 Drosophila genes whose mRNAs are most abundant in elongating spermatids. By single-cyst quantitative RT-PCR...
- A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development
[作者：Rodrigues, CO; Nerlick, ST; White, EL; Cleveland, JL; King, ML,期刊：Development, 页码：1903-1911 , 文章类型： Article，,卷期：2008年135-11]
- Myc-deficient mice fail to develop normal vascular networks and Myc-deficient embryonic stem cells fail to provoke a tumor angiogenic response when injected into immune compromised mice. However, the molecular underpinni...
- The gradient of Gurken, a long-range morphogen, is directly regulated by Cbl-mediated endocytosis
[作者：Chang, WL; Liou, W; Pen, HC; Chou, HY; Chang, YW; Li, WH; Chiang, W; Pai, LM,期刊：Development, 页码：1923-1933 , 文章类型： Article，,卷期：2008年135-11]
- The asymmetric localization of gurken mRNA and post-translational sorting mechanisms are responsible for the polar distribution of Gurken protein in Drosophila. However, endocytosis of Egfr, the receptor for Gurken in th...
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