- Temporal progression of hypothalamic patterning by a dual action of BMP
[作者:Ohyama, K; Das, R; Placzek, M,期刊:Development, 页码:3325-3331 , 文章类型: Article,,卷期:2008年135-20]
- In the developing chick hypothalamus, Shh and BMPs are expressed in a spatially overlapping, but temporally consecutive, manner. Here, we demonstrate how the temporal integration of Shh and BMP signalling leads to the la...
- A functional role for semaphorin 4D/plexin B1 interactions in epithelial branching morphogenesis during organogenesis
[作者:Korostylev, A; Worzfeld, T; Deng, SH; Friedel, RH; Swiercz, JM; Vodrazka, P; Maier, V; Hirschberg, A; Ohoka, Y; Inagaki, S; Offermanns, S; Kuner, R,期刊:Development, 页码:3333-3343 , 文章类型: Article,,卷期:2008年135-20]
- Semaphorins and their receptors, plexins, carry out important functions during development and disease. In contrast to the well-characterized plexin A family, however, very little is known about the functional relevance ...
- Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development
[作者:Mravec, J; Kubes, M; Bielach, A; Gaykova, V; Petrasek, J; Skupa, P; Chand, S; Benkova, E; Zazimalova, E; Friml, J,期刊:Development, 页码:3345-3354 , 文章类型: Article,,卷期:2008年135-20]
- The signalling molecule auxin controls plant morphogenesis via its activity gradients, which are produced by intercellular auxin transport. Cellular auxin efflux is the rate-limiting step in this process and depends on P...
- Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand (vol 132, pg 133, 2005)
[作者:Tian, H; Jeong, J; Harfe, BD; Tabin, CJ; McMahon, AP,期刊:Development, 页码:3471-3472 , 文章类型: Correction,,卷期:2008年135-20]
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- A dual requirement for Iroquois genes during Xenopus kidney development (vol 135, pg 3197, 2008)
[作者:Alarcon, P; Rodriguez-Seguel, E; Fernandez-Gonzalez, A; Rubio, R; Gomez-Skarmeta, JL,期刊:Development, 页码:3473-3473 , 文章类型: Correction,,卷期:2008年135-20]
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- odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate
[作者:Mudumana, SP; Hentschel, D; Liu, Y; Vasilyev, A; Drummond, IA,期刊:Development, 页码:3355-3367 , 文章类型: Article,,卷期:2008年135-20]
- The kidney and vasculature are intimately linked both functionally and during development, when nephric and blood/vascular progenitor cells occupy adjacent bands of mesoderm in zebrafish and frog embryos. Developmental m...
- Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors
[作者:Wassef, MA; Chomette, D; Pouilhe, M; Stedman, A; Havis, E; Dinh, CDT; Schneider-Maunoury, S; Gilardi-Hebenstreit, P; Charnay, P; Ghislain, J,期刊:Development, 页码:3369-3378 , 文章类型: Article,,卷期:2008年135-20]
- The morphogenesis of the vertebrate hindbrain involves the generation of metameric units called rhombomeres (r), and Krox20 encodes a transcription factor that is expressed in r3 and r5 and plays a major role in this seg...
- Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5
[作者:Mao, CA; Wang, SW; Pan, P; Klein, WH,期刊:Development, 页码:3379-3388 , 文章类型: Article,,卷期:2008年135-20]
- Retinal progenitor cells (RPCs) express basic helix-loop-helix ( bHLH) factors in a strikingly mosaic spatiotemporal pattern, which is thought to contribute to the establishment of individual retinal cell identity. Here,...
- Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
[作者:Satyanarayana, A; Berthet, C; Lopez-Molina, J; Coppola, V; Tessarollo, L; Kaldis, P,期刊:Development, 页码:3389-3400 , 文章类型: Article,,卷期:2008年135-20]
- It was believed that Cdk2-cyclin E complexes are essential to drive cells through the G1-S phase transition. However, it was discovered recently that the mitotic kinase Cdk1 (Cdc2a) compensates for the loss of Cdk2. In t...
- Dopaminergic neuronal cluster size is determined during early forebrain patterning
[作者:Russek-Blum, N; Gutnick, A; Nabel-Rosen, H; Blechman, J; Staudt, N; Dorsky, RI; Houart, C; Levkowitz, G,期刊:Development, 页码:3401-3413 , 文章类型: Article,,卷期:2008年135-20]
- We have explored the effects of robust neural plate patterning signals, such as canonical Wnt, on the differentiation and configuration of neuronal subtypes in the zebrafish diencephalon at single-cell resolution. Surpri...
- Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish
[作者:Wang, LB; Sewell, WF; Kim, SD; Shin, JT; MacRae, CA; Zon, LI; Seidman, JG; Seidman, CE,期刊:Development, 页码:3425-3434 , 文章类型: Article,,卷期:2008年135-20]
- To investigate the mechanisms by which mutations in the human transcriptional co-activator EYA4 gene cause sensorineural hearing loss that can occur in association with dilated cardiomyopathy, we studied eya4 expression ...
- Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast
[作者:Cheng, X; Huber, TL; Chen, VC; Gadue, P; Keller, GM,期刊:Development, 页码:3447-3458 , 文章类型: Article,,卷期:2008年135-20]
- During embryonic development, the establishment of the primitive erythroid lineage in the yolk sac is a temporally and spatially restricted program that defines the onset of hematopoiesis. In this report, we have used th...
- Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon
[作者:Omodei, D; Acampora, D; Mancuso, P; Prakash, N; Di Giovannantonio, LG; Wurst, W; Simeone, A,期刊:Development, 页码:3459-3470 , 文章类型: Article,,卷期:2008年135-20]
- Meso-diencephalic dopaminergic (mdDA) neurons control voluntary movement, cognition and the reward response, and their degeneration is associated with Parkinson's disease (PD). Prospective cell transplantation therapies ...
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