- Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential
[作者:Ruan, KH; So, SP; Wu, HJ; Cervantes, V,期刊:Archives of Biochemistry and Biophysics , 页码:41-50 , 文章类型: Article,,卷期:2008年480-1]
- Recently, we reported that a novel hybrid enzyme (TriCat enzyme), engineered by linking human cyclooxygenase-2 (COX-2) with prostacyclin (PGl(2)) synthase (PGIS) together through a transmembrane domain, was able to direc...
- The structure of urease activation complexes examined by flexibility analysis, mutagenesis, and small-angle X-ray scattering
[作者:Quiroz-Valenzuela, S; Sukuru, SCK; Hausinger, RP; Kuhn, LA; Heller, WT,期刊:Archives of Biochemistry and Biophysics , 页码:51-57 , 文章类型: Article,,卷期:2008年480-1]
- Conformational changes of Klebsiella aerogenes urease apoprotein (UreABC)(3) induced upon binding of the UreD and UreF accessory proteins were examined by a combination of flexibility analysis, mutagenesis, and small-ang...
- Human mevalonate diphosphate decarboxylase: Characterization, investigation of the mevalonate diphosphate binding site, and crystal structure
[作者:Voynova, NE; Fu, ZJ; Battaile, KP; Herdendorf, TJ; Kim, JJP; Miziorko, HM,期刊:Archives of Biochemistry and Biophysics , 页码:58-67 , 文章类型: Article,,卷期:2008年480-1]
- Expression in Escherichia coli of his-tagged human mevalonate diphosphate decarboxylase (hMDD) has expedited enzyme isolation, characterization, functional investigation of the mevalonate diphosphate binding site, and cr...
- Formation of phosphatidic acid in stressed mitochondria
[作者:Yurkova, IL; Stuckert, F; Kisel, MA; Shadyro, OI; Arnhold, J; Huster, D,期刊:Archives of Biochemistry and Biophysics , 页码:17-26 , 文章类型: Article,,卷期:2008年480-1]
- Mitochondria are an important intracellular source of ROS as well as a sensitive target for oxidative damage Under certain pathological conditions such as iron or copper overload. Mitochondrial membranes are rich in the ...
- Resveratrol protects against oxidative injury induced by H2O2 in acute hippocampal slice preparations from Wistar rats
[作者:de Almeida, LMV; Leite, MC; Thomazi, AP; Battu, C; Nardin, P; Tortorelli, LS; Zanotto, C; Posser, T; Wofchuk, ST; Leal, RB; Goncalves, CA; Gottfried, C,期刊:Archives of Biochemistry and Biophysics , 页码:27-32 , 文章类型: Article,,卷期:2008年480-1]
- There is a current interest in dietary compounds (such as trans-resveratrol) that can inhibit or reverse oxidative stress, the common pathway for a variety of brain disorders, including Alzheimer's disease and stroke. Th...
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