- Development of Extracellular Signal-Regulated Kinase Inhibitors
[作者：Burkhard, K; Smith, S; Deshmukh, R; MacKerell, AD; Shapiro, P,期刊：Current Topics in Medicinal Chemistry, 页码：678-689 , 文章类型： Review，,卷期：2009年9-8]
- Activation of the extracellular signal-regulated kinase (ERK) signaling pathway has been implicated in mediating a diverse array of cellular functions including cell differentiation, proliferation, and inflammatory respo...
- ITK Inhibitors in Inflammation and Immune-Mediated Disorders
[作者：Sahu, N; August, A,期刊：Current Topics in Medicinal Chemistry, 页码：690-703 , 文章类型： Review，,卷期：2009年9-8]
- Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine recept...
- IRAK-4 Inhibitors for Inflammation
[作者：Wang, ZL; Wesche, H; Stevens, T; Walker, N; Yeh, WC,期刊：Current Topics in Medicinal Chemistry, 页码：724-737 , 文章类型： Review，,卷期：2009年9-8]
- Interleukin-1 receptor-associated kinases (IRAKs) are key components in the signal transduction pathways utilized by interleukin-1 receptor (IL-1R), interleukin-18 receptor (IL-18R), and Toll-like receptors (TLRs). Out o...
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