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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Stroke as a Target in Medicinal Chemistry and Drug Discovery [作者：Tuttolomondo, A,期刊：Current Topics in Medicinal Chemistry, 页码：1237-1239 , 文章类型： Editorial Material，,卷期：2009年9-14] Inflammation as a Therapeutic Target in Acute Ischemic Stroke Treatment [作者：Tuttolomondo, A; Di Sciacca, R; Di Raimondo, D; Renda, C; Pinto, A; Licata, G,期刊：Current Topics in Medicinal Chemistry, 页码：1240-1260 , 文章类型： Review，,卷期：2009年9-14] Animal models of focal ischaemia induced by middle cerebral artery occlusion (MCAO) provide most evidence for cellular inflammatory responses in stroke. Permanent MCAO results in a modest neutrophil infiltration at 24 h ... Glucose Blood Levels as a Therapeutic Target in Acute Ischaemic Stroke Setting [作者：Guyomard, V; Jamieson, EI; Myint, PK,期刊：Current Topics in Medicinal Chemistry, 页码：1261-1277 , 文章类型： Review，,卷期：2009年9-14] Ischaemic stroke is extremely common in western societies contributing to 70-85% of strokes, one of the leading causes of mortality and long-term disability. Despite advancement in preventive measures, the total number o... Blood Pressure as a Therapeutic Target in Stroke [作者：Armario, P; de la Sierra, A,期刊：Current Topics in Medicinal Chemistry, 页码：1278-1284 , 文章类型： Review，,卷期：2009年9-14] Stroke, as a clinical manifestation of the cardiovascular diseases, is one of the leading causes of death and disability in both developed and developing countries. Hypertension is by far, the most important risk factor ... Thrombolysis for Acute Ischemic Stroke [作者：Uyttenboogaart, M; De Keyser, J; Luijckx, G,期刊：Current Topics in Medicinal Chemistry, 页码：1285-1290 , 文章类型： Review，,卷期：2009年9-14] In the last decennium, thrombolytic therapy has changed the management of acute ischemic stroke. Randomized clinical studies have demonstrated that intravenous thrombolysis with tissue plasminogen activator improves func... Dyslipidemia as a Risk Factor for Ischemic Stroke [作者：Tziomalos, K; Athyros, VG; Karagiannis, A; Mikhailidis, DP,期刊：Current Topics in Medicinal Chemistry, 页码：1291-1297 , 文章类型： Review，,卷期：2009年9-14] Ischemic stroke is a major cause of morbidity and mortality. Whereas dyslipidemia is a major risk factor for coronary heart disease (CHD), its role in the pathogenesis of ischemic stroke is less clear. Epidemiological st... Antiplatelet Treatment in Ischemic Stroke Treatment [作者：Pinto, A; Di Raimondo, D; Tuttolomondo, A; Di Sciacca, R; Arnao, V; La Placa, S; Milio, G; Miceli, S; Licata, G,期刊：Current Topics in Medicinal Chemistry, 页码：1298-1316 , 文章类型： Review，,卷期：2009年9-14] Antiplatelets represent a diverse group of agents that share the ability to reduce platelet activity through a variety of mechanisms. Antithrombotic agents are effective in the secondary prevention of ischemic strokes. M... Neuron Protection as a Therapeutic Target in Acute Ischemic Stroke [作者：Tuttolomondo, A; Di Sciacca, R; Di Raimondo, D; Arnao, V; Renda, C; Pinto, A; Licata, G,期刊：Current Topics in Medicinal Chemistry, 页码：1317-1334 , 文章类型： Review，,卷期：2009年9-14] Involvement of various neurotransmitters and neuromodulators have been shown to contribute to the ischemic injury and neuronal death associated with stroke Role of excitatory amino acid receptor activation, calcium overl...