- Conformationally Locked Calixarene-Based Histone Deacetylase Inhibitors
[作者:CHINI MARIA GIOVANNA; TERRACCIANO STEFANIA; RICCIO RAFFAELE; BIFULCO GIUSEPPE; CIAO ROBERTA; GAETA CARMINE; TROISI FRANCESCO; NERI PLACIDO,期刊:Organic Letters, 页码:5382-5385 , 文章类型: Article,,卷期:2010年12-23]
- Alkyl- and arylamidocalix[4]arene derivatives 1-11 have been designed and theoretically evaluated by docking studies as potential histone. deacetylase inhibitors (HDACi). On the basis of the trimodal distribution of the ...
- Di- and Trisubstituted gamma-Lactams via Rh(II)-carbenoid Reaction of N-C-alpha-Branched, N-Bis(trimethylsilyl)methyl alpha-Diazoamides. Synthesis of (+/-)-alpha-Allokainic Acid
[作者:ZHANG BAO; WEE ANDREW G H,期刊:Organic Letters, 页码:5386-5389 , 文章类型: Article,,卷期:2010年12-23]
- AcyclicN-C-alpha-branched, N-bis(trimethylsilyl)methyl (N-BTMSM) diazoamides undergo regio-, chemo-, and diastereoselective Rh(II)-carbenoid C-H insertion to give 4,5-disubstituted and 3,4,5-trisubstituted gamma-lactams....
- Preparation of 2-Magnesiated 1,3,5-Triazines via an Iodine-Magnesium Exchange
[作者:PENG ZHIHUA; HAAG BENJAMIN A; KNOCHEL PAUL,期刊:Organic Letters, 页码:5398-5401 , 文章类型: Article,,卷期:2010年12-23]
- Functionalized iodo- and diiodo-1,3,5-triazine derivatives readily undergo an I/Mg exchange with BuMgCl, sBuMgCl, or OctMgBr at low temperatures. furnishing 2-magnesiated and 2-zincated 1,3,5-triazines (after transmetala...
|