- 5-HT1 receptor augmentation strategies as enhanced efficacy therapeutics for psychiatric disorders
[作者:Dawson, LA; Bromidge, SM,期刊:Current Topics in Medicinal Chemistry, 页码:1008-1023 , 文章类型: Review,,卷期:2008年8-12]
Since the initial observations linking 5-HT to psychiatric illness, evidence for a role of 5-HT and, in particular, a decreased brain serotonergic function in the pathology of a plethora of related disorders, has grow...
- D-2 receptor partial agonists: Treatment of CNS disorders of dopamine function
[作者:Kehne, JH; Andree, TH; Heinrich, JN,期刊:Current Topics in Medicinal Chemistry, 页码:1068-1088 , 文章类型: Review,,卷期:2008年8-12]
A remarkable diversity of psychiatric and neurological disorders have been associated with dysfunction of dopamine (DA)-containing neurons, including schizophrenia, bipolar disorder (BD), Parkinson's disease (PD), and...
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