- Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors
[作者：Schuller, U; Zhao, Q; Godinho, SA; Heine, VA; Medema, RH; Pellman, D; Rowitch, DH,期刊：Molecular and Cellular Biology, 页码：8259-8270 , 文章类型： Article，,卷期：2007年27-23]
- The forkhead transcription factor FoxM1 has been reported to regulate, variously, proliferation and/or spindle formation during the G(2)/M transition of the cell cycle. Here we define specific functions of FoxM1 during b...
- Src-dependent phosphorylation of ASAP1 regulates podosomes
[作者：Bharti, S; Inoue, H; Bharti, K; Hirsch, DS; Nie, Z; Yoon, HY; Artym, V; Yamada, KA; Mueller, SC; Barr, VA; Randazzo, PA,期刊：Molecular and Cellular Biology, 页码：8271-8283 , 文章类型： Article，,卷期：2007年27-23]
- Invadopodia are Src-induced cellular structures that are thought to mediate tumor invasion. ASAP1, an Arf GTPase-activating protein (GAP) containing Src homology 3 (SH3) and Bin, amphiphysin, and RVS161/167 (BAR) domains...
- Drosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythms
[作者：Muskus, MJ; Preuss, F; Fan, JY; Bjes, ES; Price, JL,期刊：Molecular and Cellular Biology, 页码：8049-8064 , 文章类型： Article，,卷期：2007年27-23]
- A mutation (K38R) which specifically eliminates kinase activity was created in the Drosophila melanogaster W gene (doubletime [dbt]). In vitro, DBT protein carrying the K38R mutation (DBTK/R) interacted with Period prote...
- G protein-coupled receptor 83 is dispensable for the development and function of regulatory T cells
[作者：Lu, LF; Gavin, MA; Rasmussen, JP; Rudensky, AY,期刊：Molecular and Cellular Biology, 页码：8065-8072 , 文章类型： Article，,卷期：2007年27-23]
- Global analyses of gene expression in regulatory T (Treg) cells, whose development is critically dependent upon the transcription factor Foxp3, have provided many clues as to the molecular mechanisms these cells employ t...
- Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: Distinct roles for Ship2 and PTEN
[作者：Mandl, A; Sarkes, D; Carricaburu, V; Jung, V; Rameh, L,期刊：Molecular and Cellular Biology, 页码：8098-8112 , 文章类型： Article，,卷期：2007年27-23]
- Phosphoinositide 3-kinase (PI3K) activation and synthesis of phosphatidylinositol-3,4-bisphosphate (PI-3,4-P-2) and phosphatidylinositol-3,4,5-trisphosphate (PI-3,4,5-P-3) lipids mediate growth factor signaling that lead...
- Identification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling function
[作者：Shin, J; Gu, C; Park, E; Park, S,期刊：Molecular and Cellular Biology, 页码：8113-8126 , 文章类型： Article，,卷期：2007年27-23]
- Eph receptors and ephrins have been implicated in a variety of cellular processes, including morphology and motility, because of their ability to modulate intricate signaling networks. Here we show that the phosphotyrosi...
- RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-Cell signaling responses
[作者：Ruiz, S; Santos, E; Bustelo, XR,期刊：Molecular and Cellular Biology, 页码：8127-8142 , 文章类型： Article，,卷期：2007年27-23]
- The Ras pathway is critical for the development and function of T lymphocytes. The stimulation of this GTPase in T cells occurs primarily through the Vav1- and phospholipase C-gamma 1-dependent activation of RasGRP1, a d...
- Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c
[作者：Potthoff, MJ; Arnold, MA; McAnally, J; Richardson, JA; Bassel-Duby, R; Olson, EN,期刊：Molecular and Cellular Biology, 页码：8143-8151 , 文章类型： Article，,卷期：2007年27-23]
- Myocyte enhancer factor 2 (MEF2) transcription factors cooperate with the MyoD family of basic helixloop-helix (bHLH) transcription factors to drive skeletal muscle development during embryogenesis, but little is known a...
- Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
[作者：Fujino, G; Noguchi, T; Matsuzawa, A; Yamauchi, S; Saitoh, M; Takeda, K; Ichijo, H,期刊：Molecular and Cellular Biology, 页码：8152-8163 , 文章类型： Article，,卷期：2007年27-23]
- Apoptosis signal-regulating kinase 1 (ASK1), a member of the mitogen-activated protein kinase kinase kinase family, plays pivotal roles in reactive oxygen species (ROS)-induced cellular responses. In resting cells, endog...
- Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN
[作者：Han, MY; Kosako, H; Watanabe, T; Hattori, S,期刊：Molecular and Cellular Biology, 页码：8190-8204 , 文章类型： Article，,卷期：2007年27-23]
- Extracellular signal -regulated kinase (ERK) is important for various cellular processes, including cell migration. However, the detailed molecular mechanism by which ERK promotes cell motility remains elusive. Here we c...
- Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer
[作者：Li, H; Vogel, H; Holcomb, VB; Gu, YS; Hasty, P,期刊：Molecular and Cellular Biology, 页码：8205-8214 , 文章类型： Article，,卷期：2007年27-23]
- Ku70 forms a heterodimer with Ku80, called Ku, that is critical for repairing DNA double-stand breaks by nonhomologous end joining and for maintaining telomeres. Mice with either gene mutated exhibit similar phenotypes t...
- Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes
[作者：Faul, C; Dhume, A; Schecter, AD; Mundel, P,期刊：Molecular and Cellular Biology, 页码：8215-8227 , 文章类型： Article，,卷期：2007年27-23]
- Spatial and temporal resolution of intracellular signaling can be achieved by compartmentalizing transduction units. Myopodin is a dual-compartment, actin-bundling protein that shuttles between the nucleus and the Z-disc...
- Mutant p53 attenuates the SMAD-dependent transforming growth factor beta 1 (TGF-beta 1) signaling pathway by repressing the expression of TGF-beta receptor type II
[作者：Kalo, E; Buganim, Y; Shapira, KE; Besserglick, H; Goldfinger, N; Weisz, L; Stambolsky, P; Henis, YI; Rotter, V,期刊：Molecular and Cellular Biology, 页码：8228-8242 , 文章类型： Article，,卷期：2007年27-23]
- Both transforming growth factor beta (TGF-beta) and p53 have been shown to control normal cell growth. Acquired mutations either in the TGF-beta signaling pathway or in the p53 protein were shown to induce malignant tran...
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