- Deconstructing export of malaria proteins
[作者：Bonnefoy, S; Menard, R,期刊：Cell, 页码：20-22 , 文章类型： Editorial Material，,卷期：2008年134-1]
- The virulence of the malaria parasite Plasmodium falciparum is mediated by parasite proteins exported to the surface of infected erythrocytes. In this issue, Maier et al. ( 2008) report a screen of malaria parasite genes...
- Interchromosomal huddle kickstarts antiviral defense
[作者：Schoenfelder, S; Fraser, P,期刊：Cell, 页码：14-16 , 文章类型： Editorial Material，,卷期：2008年134-1]
- Long-distance chromosomal interactions are emerging as a potential mechanism of gene expression control. In this issue, Apostolou and Thanos (2008) describe how viral infection elicits interchromosomal associations betwe...
- Clearing the way for unpaused polymerases
[作者：Weake, VM; Workman, JL,期刊：Cell, 页码：16-18 , 文章类型： Editorial Material，,卷期：2008年134-1]
- Heat shock loci in the polytene chromosomes of the fruit fly Drosophila undergo a characteristic change in appearance that coincides with the onset of gene expression. Petesch and Lis ( 2008) now show that nucleosomes ar...
- Rab5 and Rac team up in cell motility
[作者：Zech, T; Machesky, L,期刊：Cell, 页码：18-20 , 文章类型： Editorial Material，,卷期：2008年134-1]
- Cell motility requires actin assembly mediated by Rac, a Rho family GTPase. In this issue, Palamidessi et al. (2008) show that Rab5-directed trafficking of Rac to the cell membrane is required for Rac-mediated actin asse...
- The mitochondrial proteom: From inventory to function
[作者：Meisinger, C; Sickmann, A; Pfanner, N,期刊：Cell, 页码：22-24 , 文章类型： Editorial Material，,卷期：2008年134-1]
- Mitochondria are central to cellular energetics, metabolism, and signaling. In this issue, Pagliarini et al. (2008) report the largest compendium of mammalian mitochondrial proteins to date. Together with proteomic studi...
- Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci
[作者：Petesch, SJ; Lis, JT,期刊：Cell, 页码：74-84 , 文章类型： Article，,卷期：2008年134-1]
- To efficiently transcribe genes, RNA Polymerase II (Pol II) must overcome barriers imposed by nucleosomes and higher- order chromatin structure. Many genes, including Drosophila melanogaster Hsp70, undergo changes in chr...
- A mitochondrial protein compendium elucidates complex I disease biology
[作者：Pagliarini, DJ; Calvo, SE; Chang, B; Sheth, SA; Vafai, SB; Ong, SE; Walford, GA; Sugiana, C; Boneh, A; Chen, WK; Hill, DE; Vidal, M; Evans, JG; Thorburn, DR; Carr, SA; Mootha, VK,期刊：Cell, 页码：112-123 , 文章类型： Article，,卷期：2008年134-1]
- Mitochondria are complex organelles whose dysfunction underlies a broad spectrum of human diseases. Identifying all of the proteins resident in this organelle and understanding how they integrate into pathways represent ...
- LXR signaling couples sterol metabolism to proliferation in the acquired immune response
[作者：Bensinger, SJ; Bradley, MN; Joseph, SB; Zelcer, N; Janssen, EM; Hausner, MA; Shih, R; Parks, JS; Edwards, PA; Jamieson, BD; Tontonoz, P,期刊：Cell, 页码：97-111 , 文章类型： Article，,卷期：2008年134-1]
- Cholesterol is essential for membrane synthesis; however, the mechanisms that link cellular lipid metabolism to proliferation are incompletely understood. We demonstrate here that cellular cholesterol levels in dividing ...
- Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration
[作者：Palamidessi, A; Frittoli, E; Garre, M; Faretta, M; Mione, M; Testa, I; Diaspro, A; Lanzetti, L; Scita, G; Di Fiore, PP,期刊：Cell, 页码：135-147 , 文章类型： Article，,卷期：2008年134-1]
- The small GTPases, Rab5 and Rac, are essential for endocytosis and actin remodeling, respectively. Coordination of these processes is critical to achieve spatial restriction of intracellular signaling, which is essential...
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