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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共23条记录   Bacterial Transition Metal P(1B)-ATPases: Transport Mechanism and Roles in Virulence [作者：Arguello, JM; Gonzalez-Guerrero, M; Raimunda, D,期刊：Biochemistry, 页码：9940-9949 , 文章类型： Article，,卷期：2011年50-46] P(1B)-type ATPases are polytopic membrane proteins that couple the hydrolysis of ATP to the efflux of cytoplasmic transition metals. This paper reviews recent progress in out understanding of the structure and function o... The Enzyme Function Initiative [作者：Gerlt, JA; Allen, KN; Almo, SC; Armstrong, RN; Babbitt, PC; Cronan, JE; Dunaway-Mariano, D; Imker, HJ; Jacobson, MP; Minor, W; Poulter, CD; Raushel, FM; Sali, A; Shoichet, BK; Sweedler, JV,期刊：Biochemistry, 页码：9950-9962 , 文章类型： Article，,卷期：2011年50-46] The Enzyme Function Initiative (EFI) was recently established to address the challenge of assigning reliable functions to enzymes discovered in bacterial genome projects; in this Current Topic, we review the structure an... Analysis of Conformational Changes in the DNA Junction-Resolving Enzyme T7 Endonuclease I on Binding a Four-Way Junction Using EPR [作者：Freeman, ADJ; Ward, R; El Mkami, H; Lilley, DMJ; Norman, DG,期刊：Biochemistry, 页码：9963-9972 , 文章类型： Article，,卷期：2011年50-46] The four-way (Holiday) DNA junction is the central intermediate in homologous recombination. It is ultimately resolved into two nicked-duplex species by the action of a junction-resolving enzyme. These enzymes are highly... The Divalent Cations Ca(2+) and Mg(2+) Play Specific Roles in Stabilizing Histone-DNA Interactions within Nucleosomes That Are Partially Redundant with the Core Histone Tail Domains [作者：Yang, Z; Hayes, JJ,期刊：Biochemistry, 页码：9973-9981 , 文章类型： Article，,卷期：2011年50-46] We previously reported that reconstituted nucleosomes undergo sequence-dependent translational repositioning upon removal of the core histone tail domains under physiological conditions, indicating that the tails influen... A Calorimetric and Spectroscopic Comparison of the Effects of Lathosterol and Cholesterol on the Thermotropic Phase Behavior and Organization of Dipalmitoylphosphatidylcholine Bilayer Membranes [作者：Benesch, MGK; Mannock, DA; Lewis, RNAH; McElhaney, RN,期刊：Biochemistry, 页码：9982-9997 , 文章类型： Article，,卷期：2011年50-46] We performed differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopic measurements to study the effects of lathosterol (Lath) on the thermotropic phase behavior and organization of dipa... Post-Translational Modifications and Lipid Binding Profile of Insect Cell-Expressed Full-Length Mammalian Synaptotagmin 1 [作者：Vrljic, M; Strop, P; Hill, RC; Hansen, KC; Chu, S; Brunger, AT,期刊：Biochemistry, 页码：9998-10012 , 文章类型： Article，,卷期：2011年50-46] Synaptotagmin 1 (Syt1) is a Ca(2+) sensor for SNARE-mediated, Ca(2+)-triggered synaptic vesicle fusion in neurons. It is composed of luminal, transmembrane, linker, and two Ca(2+)-binding (C2) domains. Here we describe e... Solid-State Nuclear Magnetic Resonance (NMR) Spectroscopy of Human Immunodeficiency Virus gp41 Protein That Includes the Fusion Peptide: NMR Detection of Recombinant Fgp41 in Inclusion Bodies in Whole Bacterial Cells and Structural Characterization of Purified and Membrane-Associated Fgp41 [作者：Vogel, EP; Curtis-Fisk, J; Young, KM; Weliky, DP,期刊：Biochemistry, 页码：10013-10026 , 文章类型： Article，,卷期：2011年50-46] Human immunodeficiency virus (HIV) infection of a host cell begins with fusion of the HIV and host cell membranes and is mediated by the gp41 protein, a single-pass integral membrane protein of HIV. The 175 N-terminal re... Probing the Dynamics of a His73-Heme Alkaline Transition in a Destabilized Variant of Yeast Iso-1-cytochrome c with Conformationally Gated Electron Transfer Methods [作者：Bandi, S; Bowler, BE,期刊：Biochemistry, 页码：10027-10040 , 文章类型： Article，,卷期：2011年50-46] The alkaline transition of cytochrome c involves substitution of the Met80 heme ligand of the native state with a lysine ligand from a surface Omega-loop (residues 70 to 85). The standard mechanism for the alkaline trans... Allosteric Activation of Cytochrome P450 3A4 by alpha-Naphthoflavone: Branch Point Regulation Revealed by Isotope Dilution Analysis [作者：Woods, CM; Fernandez, C; Kunze, KL; Atkins, WM,期刊：Biochemistry, 页码：10041-10051 , 文章类型： Article，,卷期：2011年50-46] Cytochrome P450 3A4 (CYP3A4) is the dominant xenobiotic metabolizing CYP. Despite great interest in CYP enzymology, two in vitro aspects of CYP3A4 catalysis are still not well understood, namely, sequential metabolism an... Increasing Stability and Toxicity of Pseudomonas Exotoxin by Attaching an Antiproteasic Peptide [作者：Mere, J; Chopard, C; Bonhoure, A; Morlon-Guyot, J; Beaumelle, B,期刊：Biochemistry, 页码：10052-10060 , 文章类型： Article，,卷期：2011年50-46] Trypsin-like activities are present within the endocytic pathway and allow cells to inactivate a fraction of incoming toxins, such as Pseudomonas exotoxin (PE), that require endocytic uptake before reaching the cytosol t... In Calmodulin-IQ Domain Complexes, the Ca(2+)-Free and Ca(2+)-Bound Forms of the Calmodulin C-Lobe Direct the N-Lobe to Different Binding Sites [作者：Black, DJ; Persechini, A,期刊：Biochemistry, 页码：10061-10068 , 文章类型： Article，,卷期：2011年50-46] We have investigated the roles played by the calmodulin (CaM) N- and C-lobes in establishing the conformations of CaM-IQ domain complexes in different Ca(2+)-free and Ca(2+)-bound states. Our results indicate a dominant ... The Conserved Trp-Cys Hydrogen Bond Dampens the "Push Effect" of the Heme Cysteinate Proximal Ligand during the First Catalytic Cycle of Nitric Oxide Synthase [作者：Lang, J; Santolini, J; Couture, M,期刊：Biochemistry, 页码：10069-10081 , 文章类型： Article，,卷期：2011年50-46] Residues surrounding and interacting with the heme proximal ligand are important for efficient catalysis by heme proteins. The nitric oxide synthases (NOSs) are thiolate-coordinated enzymes that catalyze the hydroxylatio... (S)-Styryl-alpha-alanine Used To Probe the Intermolecular Mechanism of an Intramolecular MIO-Aminomutase [作者：Wanninayake, U; DePorre, Y; Ondari, M; Walker, KD,期刊：Biochemistry, 页码：10082-10090 , 文章类型： Article，,卷期：2011年50-46] A Taxus canadensis phenylalanine aminomutase (TcPAM) catalyzes the isomerization of (S)-alpha- to (R)-beta-phenylalanine, making (E)-cinnamate (similar to 10%) as a byproduct at steady state. A currently accepted mechani... Substrate Specificity of Low-Molecular Mass Bacterial DD-Peptidases [作者：Nemmara, VV; Dzhekieva, L; Sarkar, KS; Adediran, SA; Duez, C; Nicholas, RA; Prattt, RF,期刊：Biochemistry, 页码：10091-10101 , 文章类型： Article，,卷期：2011年50-46] The bacterial DD-peptidases or penicillin-binding proteins (PBPs) catalyze the formation and regulation of cross-links in peptidoglycan biosynthesis. They are classified into two groups, the high-molecular mass (HMM) and... Characterization of Purified New Delhi Metallo-beta-lactamase-1 [作者：Thomas, PW; Zheng, M; Wu, SS; Guo, H; Liu, DL; Xu, DG; Fast, W,期刊：Biochemistry, 页码：10102-10113 , 文章类型： Article，,卷期：2011年50-46] New Delhi metallo-beta-lactmase-1 (NDM-1) has recently emerged as a global threat because of its ability to confer resistance to almost all clinically used beta-lactam antibiotics, its presence within an easily transmiss... Conformational Basis for Substrate Recruitment in Protein Tyrosine Phosphatase 10D [作者：Madan, LL; Gopal, B,期刊：Biochemistry, 页码：10114-10125 , 文章类型： Article，,卷期：2011年50-46] The coordinated activity of protein tyrosine phosphatases (PTPs) is crucial for the initiation, modulation, and termination of diverse cellular processes. The catalytic activity of this protein depends on a nucleophilic ...