- Retinoid Receptors and Therapeutic Applications of RAR/RXR Modulators
[作者:le Maire, A; Alvarez, S; Shankaranarayanan, P; de Lera, AR; Bourguet, W; Gronemeyer, H,期刊:Current Topics in Medicinal Chemistry, 页码:505-527 , 文章类型: Review,,卷期:2012年12-6]
- Retinoic acid receptors (RARs) are ligand-controlled transcription factors that function as heterodimers with retinoid X receptors (RXRs) to regulate cell growth, differentiation, survival and death. Due to their regulat...
- Current Status of Vitamin D Signaling and Its Therapeutic Applications
[作者:Carlberg, C; Molnar, F,期刊:Current Topics in Medicinal Chemistry, 页码:528-547 , 文章类型: Review,,卷期:2012年12-6]
- Vitamin D and in particular its biologically most active metabolite, 1 alpha,25-dihydroxyvitamin D-3 (1 alpha,25(OH)(2)D-3), are central endocrine molecules that influence many aspects of human physiology, which are not ...
- Molecular Determinants of Gastrointestinal and Liver Cancers: Role of Bile Acid Activated Nuclear Receptors
[作者:Renga, B; Mencarelli, A; Cipriani, S; Distrutti, E,期刊:Current Topics in Medicinal Chemistry, 页码:625-636 , 文章类型: Review,,卷期:2012年12-6]
- Invasion and metastasis are critical determinants of gastrointestinal and liver cancers morbidity. Genes and molecules participating in these steps (e. g. growth factors and their receptors, cell cycle regulators, cell a...
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