- Cooperative effect of p21(Cip1/WAF-1) and 14-3-3 sigma on cell cycle arrest and apoptosis induction by p14(ARF)
[作者:Hemmati, PG; Normand, G; Gillissen, B; Wendt, J; Doerken, B; Daniel, PT,期刊:Oncogene, 页码:6707-6719 , 文章类型: Article,,卷期:2008年27-53]
- P14(ARF) (p19(ARF) in the mouse) plays a central role in the regulation of cellular proliferation. Although the capacity of p14(ARF) to induce a cell cycle arrest in G1 phase depends on a functional p53/p21-signaling axi...
- Cyclin D1 in low-dose radiation-induced adaptive resistance
[作者:Ahmed, KM; Fan, M; Nantajit, D; Cao, N; Li, JJ,期刊:Oncogene, 页码:6738-6748 , 文章类型: Article,,卷期:2008年27-53]
- Cyclin D1 is involved in cell-cycle arrest in DNA-damage response. This study tested the hypothesis that cyclin D1 regulates mitochondrial apoptosis. Cycl in D1 was induced by low-dose ionizing radiation (LDIR; 10-cGy X-...
- C/EBP alpha and C/EBP epsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene
[作者:Matsushita, H; Nakajima, H; Nakamura, Y; Tsukamoto, H; Tanaka, Y; Jin, G; Yabe, M; Asai, S; Ono, R; Nosaka, T; Sugita, K; Morimoto, A; Hayashi, Y; Hotta, T; Ando, K; Miyachi, H,期刊:Oncogene, 页码:6749-6760 , 文章类型: Article,,卷期:2008年27-53]
- CCAAT/enhancer binding proteins (C/EBPs) have an important function in granulocytic differentiation, and are also involved in the leukemogenesis of acute myeloid leukemia (AML). Their involvement in myelomonocytic leukem...
- UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes (vol 27, pg 4269, 2008)
[作者:Wischermann, K; Popp, S; Moshir, S; Scharffetter-Kochanek, K; Wlaschek, M; de Gruijl, F; Hartschuh, W; Greinert, R; Volkmer, B; Faust, A; Rapp, A; Schmezer, P; Boukamp, P,期刊:Oncogene, 页码:6790-6790 , 文章类型: Correction,,卷期:2008年27-53]
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- DNA-PKcs and ATM influence generation of ionizing radiation-induced bystander signals
[作者:Hagelstrom, RT; Askin, KF; Williams, AJ; Ramaiah, L; Desaintes, C; Goodwin, EH; Ullrich, RL; Bailey, SM,期刊:Oncogene, 页码:6761-6769 , 文章类型: Article,,卷期:2008年27-53]
- The phenomenon by which irradiated cells influence non-irradiated neighboring cells, referred to as the bystander effect (BSE), is not well understood in terms of the underlying pathways involved. We sought to enlighten ...
- Deletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein REL
[作者:Leeman, JR; Weniger, MA; Barth, TF; Gilmore, TD,期刊:Oncogene, 页码:6770-6781 , 文章类型: Article,,卷期:2008年27-53]
- Misregulation of REL, a nuclear factor-kappa B family transcription factor, has been implicated in several human lymphoid malignancies. REL has a conserved N-terminal DNA-binding/dimerization domain called the Rel homolo...
- Glucose-regulated protein 78 as a novel effector of BRCA1 for inhibiting stress-induced apoptosis
[作者:Yeung, BHY; Kwan, BWY; He, QY; Lee, AS; Liu, J; Wong, AST,期刊:Oncogene, 页码:6782-6789 , 文章类型: Article,,卷期:2008年27-53]
- The tumor suppressor BRCA1 is mutated in a high percentage of familial breast and ovarian cancer, but our understanding of its mechanisms of action remains incomplete. We report here that glucose-regulated protein (GRP)-...
- Proline oxidase, a p53-induced gene, targets COX-2/PGE(2) signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
[作者:Liu, Y; Borchert, GL; Surazynski, A; Phang, JM,期刊:Oncogene, 页码:6729-6737 , 文章类型: Article,,卷期:2008年27-53]
- Proline oxidase (POX), a flavoenzyme localized at the inner mitochondrial membrane, catalyzes the first step of proline degradation by converting proline to pyrroline-5-carboxylate (P5C). POX is markedly elevated during ...
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