- Structural Determinants of MALT1 Protease Activity
[作者：Wiesmann, C; Leder, L; Blank, J; Bernardi, A; Melkko, S; Decock, A; D'Arcy, A; Villard, F; Erbel, P; Hughes, N; Freuler, F; Nikolay, R; Alves, J; Bornancin, F; Renatus, M,期刊：Journal of Molecular Biology, 页码：4-21 , 文章类型： Article，,卷期：2012年419-40910]
- The formation of the CBM (CARD11-BCL10-MALT1) complex is pivotal for antigen-receptor-mediated activation of the transcription factor NF-kappa B. Signaling is dependent on MALT1 (mucosa-associated lymphoid tissue lymphom...
- Mutations in Drosophila Myosin Rod Cause Defects in Myofibril Assembly
[作者：Salvi, SS; Kumar, RP; Ramachandra, NB; Sparrow, JC; Nongthomba, U,期刊：Journal of Molecular Biology, 页码：22-40 , 文章类型： Article，,卷期：2012年419-40910]
- The roles of myosin during muscle contraction are well studied, but how different domains of this protein are involved in myofibril assembly in vivo is far less understood. The indirect flight muscles (IFMs) of Drosophil...
- Allosteric Modulation Balances Thermodynamic Stability and Restores Function of Delta F508 CFTR
[作者：Aleksandrov, AA; Kota, P; Cui, LY; Jensen, T; Alekseev, AE; Reyes, S; He, LH; Gentzsch, M; Aleksandrov, LA; Dokholyan, NV; Riordan, JR,期刊：Journal of Molecular Biology, 页码：41-60 , 文章类型： Article，,卷期：2012年419-40910]
- Most cystic fibrosis is caused by a deletion of a single residue (F508) in CFTR (cystic fibrosis transmembrane conductance regulator) that disrupts the folding and biosynthetic maturation of the ion channel protein. Prog...
- CC2D1A Is a Regulator of ESCRT-III CHMP4B
[作者：Martinelli, N; Hartlieb, B; Usami, Y; Sabin, C; Dordor, A; Miguet, N; Avilov, SV; Ribeiro, EA; Gottlinger, H; Weissenhorn, W,期刊：Journal of Molecular Biology, 页码：75-88 , 文章类型： Article，,卷期：2012年419-40910]
- Endosomal sorting complexes required for transport (ESCRTs) regulate diverse processes ranging from receptor sorting at endosomes to distinct steps in cell division and budding of some enveloped viruses. Common to all pr...
- Engineered Oligomerization State of OmpF Protein through Computational Design Decouples Oligomer Dissociation from Unfolding
[作者：Naveed, H; Jimenez-Morales, D; Tian, J; Pasupuleti, V; Kenney, LJ; Liang, J,期刊：Journal of Molecular Biology, 页码：89-101 , 文章类型： Article，,卷期：2012年419-40910]
- Biogenesis of beta-barrel membrane proteins is a complex, multistep, and as yet incompletely characterized process. The bacterial porin family is perhaps the best-studied protein family among beta-barrel membrane protein...
- Anti-LRP/LR-Specific Antibody IgG1-iS18 Significantly Reduces Adhesion and Invasion of Metastatic Lung, Cervix, Colon and Prostate Cancer Cells
[作者：Omar, A; Reusch, U; Knackmuss, S; Little, M; Weiss, SFT,期刊：Journal of Molecular Biology, 页码：102-109 , 文章类型： Article，,卷期：2012年419-40910]
- The 37-kDa/67-kDa laminin receptor [laminin receptor precursor/high-affinity laminin receptor (LRP/LR)] is thought to play a major role in invasion and adhesion, key components of metastatic cancer. Lung cancer, cervical...
- Structure of an Essential Type IV Pilus Biogenesis Protein Provides Insights into Pilus and Type II Secretion Systems
[作者：Yamagata, A; Milgotina, E; Scanlon, K; Craig, L; Tainer, JA; Donnenberg, MS,期刊：Journal of Molecular Biology, 页码：110-124 , 文章类型： Article，,卷期：2012年419-40910]
- Type IV pili (T4Ps) are long cell surface filaments, essential for microcolony formation, tissue adherence, motility, transformation, and virulence by human pathogens. The enteropathogenic Escherichia coli bundle-forming...
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