- CNP-1 (ARRD-17), a Novel Substrate of Calcineurin, Is Critical for Modulation of Egg-Laying and Locomotion in Response to Food and Lysine Sensation in Caenorhabditis elegans
[作者：Jee, C; Choi, TW; Kalichamy, K; Yee, JZ; Song, HO; Ji, YJ; Lee, J; Lee, JI; L'Etoile, ND; Ahnn, J; Lee, SK,期刊：Journal of Molecular Biology, 页码：165-178 , 文章类型： Article，,卷期：2012年417-3]
- Calcineurin is a Ca2+/calmodulin-dependent protein phosphatase involved in calcium signaling pathways. In Caenorhabditis elegans, the loss of calcineurin activity causes pleiotropic defects including hyperadaptation of s...
- Time-Dependent Predominance of Nonhomologous DNA End-Joining Pathways during Embryonic Development in Mice
[作者：Chiruvella, KK; Sebastian, R; Sharma, S; Karande, AA; Choudhary, B; Raghavan, SC,期刊：Journal of Molecular Biology, 页码：197-211 , 文章类型： Article，,卷期：2012年417-3]
- Repair of DNA double-strand breaks (DSBs) is crucial for maintaining genomic integrity during the successful development of a fertilized egg into a whole organism. To date, the mechanism of DSB repair in postimplantation...
- A Structural Model for the Generation of Continuous Curvature on the Surface of a Retroviral Capsid
[作者：Bailey, GD; Hyun, JK; Mitra, AK; Kingston, RL,期刊：Journal of Molecular Biology, 页码：212-223 , 文章类型： Article，,卷期：2012年417-3]
- The genome of a retrovirus is surrounded by a convex protein shell, or capsid, that helps facilitate infection. The major part of the capsid surface is formed by interlocking capsid protein (CA) hexamers. We report elect...
- Identification of a Minimal Region of the HIV-1 5 '-Leader Required for RNA Dimerization, NC Binding, and Packaging
[作者：Heng, X; Kharytonchyk, S; Garcia, EL; Lu, K; Divakaruni, SS; LaCotti, C; Edme, K; Telesnitsky, A; Summers, MF,期刊：Journal of Molecular Biology, 页码：224-239 , 文章类型： Article，,卷期：2012年417-3]
- Assembly of human immunodeficiency virus type 1 (HIV-1) particles is initiated in the cytoplasm by the formation of a ribonucleoprotein complex comprising the dimeric RNA genome and a small number of viral Gag polyprotei...
- A Novel Pim-1 Kinase Inhibitor Targeting Residues That Bind the Substrate Peptide
[作者：Tsuganezawa, K; Watanabe, H; Parker, L; Yuki, H; Taruya, S; Nakagawa, Y; Kamei, D; Mori, M; Ogawa, N; Tomabechi, Y; Handa, N; Honma, T; Yokoyama, S; Kojima, H; Okabe, T; Nagano, T; Tanaka, A,期刊：Journal of Molecular Biology, 页码：240-252 , 文章类型： Article，,卷期：2012年417-3]
- A new screening method using fluorescent correlation spectroscopy was developed to select kinase inhibitors that competitively inhibit the binding of a fluorescently labeled substrate peptide. Using the method, among app...
- Phagemid Vectors for Phage Display: Properties, Characteristics and Construction
[作者：Qi, H; Lu, HQ; Qiu, HJ; Petrenko, V; Liu, AH,期刊：Journal of Molecular Biology, 页码：129-143 , 文章类型： Review，,卷期：2012年417-3]
- Phagemids are filamentous-phage-derived vectors containing the replication origin of a plasmid. Phagemids usually encode no or only one kind of coat proteins. Other structural and functional proteins necessary to accompl...
- A Structural Basis for Reversible Photoswitching of Absorbance Spectra in Red Fluorescent Protein rsTagRFP
[作者：Pletnev, S; Subach, FV; Dauter, Z; Wlodawer, A; Verkhusha, VV,期刊：Journal of Molecular Biology, 页码：144-151 , 文章类型： Article，,卷期：2012年417-3]
- rsTagRFP is the first monomeric red fluorescent protein (FP) with reversibly photoswitchable absorbance spectra. The switching is realized by irradiation of rsTagRFP with blue (440 nm) and yellow (567 nm) light, turning ...
- Micrococcal Nuclease Does Not Substantially Bias Nucleosome Mapping
[作者：Allan, J; Fraser, RM; Owen-Hughes, T; Keszenman-Pereyra, D,期刊：Journal of Molecular Biology, 页码：152-164 , 文章类型： Article，,卷期：2012年417-3]
- We have mapped sequence-directed nucleosome positioning on genomic DNA molecules using high-throughput sequencing. Chromatins, prepared by reconstitution with either chicken or frog histones, were separately digested to ...
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