- Hyporesponsiveness Following Booster Immunization With Bacterial Polysaccharides Is Caused by Apoptosis of Memory B Cells
[作者：Brynjolfsson, SF; Henneken, M; Bjarnarson, SP; Mori, E; Del Giudice, G; Jonsdottir, I,期刊：Journal of Infectious Diseases, 页码：422-430 , 文章类型： Article，,卷期：2012年205-3]
- Background. Repeated immunizations with polysaccharide ( PS) vaccines cause hyporesponsiveness through undefined mechanisms. We assessed the effects of a PS booster on immune responses, frequency, and survival of PS-spec...
- Immunization of Mice With Vibrio cholerae Outer-Membrane Vesicles Protects Against Hyperinfectious Challenge and Blocks Transmission
[作者：Bishop, AL; Tarique, AA; Patimalla, B; Calderwood, SB; Qadri, F; Camilli, A,期刊：Journal of Infectious Diseases, 页码：412-421 , 文章类型： Article，,卷期：2012年205-3]
- Background. Vibrio cholerae excreted by cholera patients is "hyperinfectious'' ( HI), which can be modeled by passage through infant mice. Immunization of adult female mice with V. cholerae outer-membrane vesicles (OMVs)...
- RGS2-Mediated Intracellular Ca2+ Level Plays a Key Role in the Intracellular Replication of Brucella abortus Within Phagocytes
[作者：Kim, DH; Lim, JJ; Lee, JJ; Kim, DG; Lee, HJ; Min, W; Kim, KD; Chang, HH; Endale, M; Rhee, MH; Watarai, M; Kim, S,期刊：Journal of Infectious Diseases, 页码：445-452 , 文章类型： Article，,卷期：2012年205-3]
- Background. Brucella abortus can proliferate within professional and nonprofessional phagocytic host cells and thereby successfully bypass the bacteriocidal effects of phagocytes. However, the intracellular survival mech...
- Impact of the 2009 Influenza Pandemic on Pneumococcal Pneumonia Hospitalizations in the United States
[作者：Weinberger, DM; Simonsen, L; Jordan, R; Steiner, C; Miller, M; Viboud, C,期刊：Journal of Infectious Diseases, 页码：458-465 , 文章类型： Article，,卷期：2012年205-3]
- Background. Infection with influenza virus increases the risk for developing pneumococcal disease. The A/H1N1 influenza pandemic in autumn 2009 provided a unique opportunity to evaluate this relationship. Background. Inf...
- Determinants of Per-Coital-Act HIV-1 Infectivity Among African HIV-1-Serodiscordant Couples
[作者：Hughes, JP; Baeten, JM; Lingappa, JR; Magaret, AS; Wald, A; de Bruyn, G; Kiarie, J; Inambao, M; Kilembe, W; Farquhar, C; Celum, C,期刊：Journal of Infectious Diseases, 页码：358-365 , 文章类型： Article，,卷期：2012年205-3]
- Background. Knowledge of factors that affect per-act infectivity of human immunodeficiency virus type 1 (HIV-1) is important for designing HIV-1 prevention interventions and for the mathematical modeling of the spread of...
- Local Innate Immune Responses and Influenza Virus Transmission and Virulence in Ferrets
[作者：Maines, TR; Belser, JA; Gustin, KM; van Hoeven, N; Zeng, H; Svitek, N; von Messling, V; Katz, JM; Tumpey, TM,期刊：Journal of Infectious Diseases, 页码：474-485 , 文章类型： Article，,卷期：2012年205-3]
- Host innate immunity is the first line of defense against invading pathogens, including influenza viruses. Ferrets are well recognized as the best model of influenza virus pathogenesis and transmission, but little is kno...
- Longitudinal Analysis of Carcinogenic Human Papillomavirus Infection and Associated Cytologic Abnormalities in the Guanacaste Natural History Study: Looking Ahead to Cotesting
[作者：Markt, SC; Rodriguez, AC; Burk, RD; Hildesheim, A; Herrero, R; Wacholder, S; Hutchinson, M; Schiffman, M,期刊：Journal of Infectious Diseases, 页码：498-505 , 文章类型： Article，,卷期：2012年205-3]
- Background. Few studies have addressed the timing of cervical cytologic abnormalities and human papillomavirus (HPV) positivity during the course of an infection. It remains largely unknown how infections detected by HPV...
- Male Circumcision and Herpes Simplex Virus Type 2 Infection in Female Partners: A Randomized Trial in Rakai, Uganda
[作者：Tobian, AAR; Kigozi, G; Redd, AD; Serwadda, D; Kong, XR; Oliver, A; Nalugoda, F; Quinn, TC; Gray, RH; Wawer, MJ,期刊：Journal of Infectious Diseases, 页码：486-490 , 文章类型： Article，,卷期：2012年205-3]
- Male circumcision reduces acquisition of herpes simplex virus type 2 (HSV-2) in men. We assessed whether male circumcision reduces HSV-2 infection among female partners. HSV-2-negative, human immunodeficiency virus-negat...
- Systemic Dissemination of Clostridium difficile Toxins A and B Is Associated With Severe, Fatal Disease in Animal Models
[作者：Steele, J; Chen, K; Sun, XM; Zhang, YR; Wang, HY; Tzipori, S; Feng, HP,期刊：Journal of Infectious Diseases, 页码：384-391 , 文章类型： Article，,卷期：2012年205-3]
- Background. Clostridium difficile infection (CDI) can cause a wide range of disease, from mild diarrhea to fulminant systemic disease. The incidence of systemic CDI with fatal consequence has increased rapidly in recent ...
- The Effects of Sepsis on Mitochondria
[作者：Garrabou, G; Moren, C; Lopez, S; Tobias, E; Cardellach, F; Miro, O; Casademont, J,期刊：Journal of Infectious Diseases, 页码：392-400 , 文章类型： Article，,卷期：2012年205-3]
- Background. Sepsis is associated with mitochondrial dysfunction and impaired oxygen consumption, which may condition clinical outcome independent of tissue oxygenation. However, mitochondrial role in sepsis severity rema...
- No Evidence of Bias in Trial Showing BCG Reduces Neonatal Mortality
[作者：Aaby, P; Roth, A; Biering-Sorensen, S; Ravn, H; Rodrigues, A; Whittle, H; Benn, CS,期刊：Journal of Infectious Diseases, 页码：694-696 , 文章类型： Letter，,卷期：2012年205-3]
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- Adoptive Transfer of Dendritic Cells Pulsed With Fasciola hepatica Antigens and Lipopolysaccharides Confers Protection Against Fasciolosis in Mice
[作者：Falcon, CR; Carranza, FA; Aoki, P; Motran, CC; Cervi, L,期刊：Journal of Infectious Diseases, 页码：506-514 , 文章类型： Article，,卷期：2012年205-3]
- Dendritic cells (DCs) can function as adjuvants able to mediate protection against different pathogens. Given that successful vaccination against Fasciola hepatica is mostly related to the induction of Th1 responses, we ...
- Anthrax Lethal and Edema Toxins Fail to Directly Impair Human Platelet Function
[作者：Chauncey, KM; Szarowicz, SE; Sidhu, GS; During, RL; Southwick, FS,期刊：Journal of Infectious Diseases, 页码：453-457 , 文章类型： Article，,卷期：2012年205-3]
- Hemorrhage is a prominent clinical manifestation of systemic anthrax. Therefore, we have examined the effects of anthrax lethal and edema toxins on human platelets. We find that anthrax lethal toxin fails to cleave its t...
- Antiviral Activity of Coxsackievirus B3 3C Protease Inhibitor in Experimental Murine Myocarditis
[作者：Yun, SH; Lee, WG; Kim, YC; Ju, ES; Lim, BK; Choi, JO; Kim, DK; Jeon, ES,期刊：Journal of Infectious Diseases, 页码：491-497 , 文章类型： Article，,卷期：2012年205-3]
- Background. We investigated the efficacy of a 3C protease inhibitor (3CPI) in a murine coxsackievirus B3 (CVB3) myocarditis model. CVB3 is a primary cause of viral myocarditis. The CVB3 genome encodes a single polyprotei...
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