- Comparative Analysis of Chromatin Binding by Sex Comb on Midleg (SCM) and Other Polycomb Group Repressors at a Drosophila Hox Gene
[作者:Wang, LJ; Jahren, N; Miller, EL; Ketel, CS; Mallin, DR; Simon, JA,期刊:Molecular and Cellular Biology, 页码:2584-2593 , 文章类型: Article,,卷期:2010年30-11]
- Sex Comb on Midleg (SCM) is a transcriptional repressor in the Polycomb group (PcG), but its molecular role in PcG silencing is not known. Although SCM can interact with Polycomb repressive complex 1 (PRC1) in vitro, bio...
- Functional and Spatial Regulation of Mitotic Centromere-Associated Kinesin by Cyclin-Dependent Kinase 1
[作者:Sanhaji, M; Friel, CT; Kreis, NN; Kramer, A; Martin, C; Howard, J; Strebhardt, K; Yuan, JP,期刊:Molecular and Cellular Biology, 页码:2594-2607 , 文章类型: Article,,卷期:2010年30-11]
- Mitotic centromere-associated kinesin (MCAK) plays an essential role in spindle formation and in correction of improper microtubule-kinetochore attachments. The localization and activity of MCAK at the centromere/kinetoc...
- The Ras Effector RASSF2 Controls the PAR-4 Tumor Suppressor
[作者:Donninger, H; Hesson, L; Vos, M; Beebe, K; Gordon, L; Sidransky, D; Liu, JW; Schlegel, T; Payne, S; Hartmann, A; Latif, F; Clark, GJ,期刊:Molecular and Cellular Biology, 页码:2608-2620 , 文章类型: Article,,卷期:2010年30-11]
- RASSF2 is a novel proapoptotic effector of K-Ras. Inhibition of RASSF2 expression enhances the transforming effects of K-Ras, and epigenetic inactivation of RASSF2 is frequently detected in mutant Ras-containing primary ...
- NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon
[作者:Coant, N; Ben Mkaddem, S; Pedruzzi, E; Guichard, C; Treton, X; Ducroc, R; Freund, JN; Cazals-Hatem, D; Bouhnik, Y; Woerther, PL; Skurnik, D; Grodet, A; Fay, M; Biard, D; Lesuffleur, T; Deffert, C; Moreau, R; Groyer, A; Krause, KH; Daniel, F; Ogier-Denis, E,期刊:Molecular and Cellular Biology, 页码:2636-2650 , 文章类型: Article,,卷期:2010年30-11]
- The homeostatic self-renewal of the colonic epithelium requires coordinated regulation of the canonical Wnt/beta-catenin and Notch signaling pathways to control proliferation and lineage commitment of multipotent stem ce...
- Genetic Analysis of Hierarchical Regulation for Gata1 and NF-E2 p45 Gene Expression in Megakaryopoiesis
[作者:Takayama, M; Fujita, R; Suzuki, M; Okuyama, R; Aiba, S; Motohashi, H; Yamamoto, M,期刊:Molecular and Cellular Biology, 页码:2668-2680 , 文章类型: Article,,卷期:2010年30-11]
- GATA1 and NF-E2 p45 are two important regulators of megakaryopoiesis. Whereas GATA1 is known to regulate the p45 gene, details of the GATA1 contribution to the spatiotemporal expression of the p45 gene remain to be eluci...
- DDB2, an Essential Mediator of Premature Senescence
[作者:Roy, N; Stoyanova, T; Dominguez-Brauer, C; Park, HJ; Bagchi, S; Raychaudhuri, P,期刊:Molecular and Cellular Biology, 页码:2681-2692 , 文章类型: Article,,卷期:2010年30-11]
- Reactive oxygen species (ROS) is critical for premature senescence, a process significant in tumor suppression and cancer therapy. Here, we reveal a novel function of the nucleotide excision repair protein DDB2 in the ac...
- Allele-Specific H3K79 Di-versus Trimethylation Distinguishes Opposite Parental Alleles at Imprinted Regions
[作者:Singh, P; Han, L; Rivas, GE; Lee, DH; Nicholson, TB; Larson, GP; Chen, TP; Szabo, PE,期刊:Molecular and Cellular Biology, 页码:2693-2707 , 文章类型: Article,,卷期:2010年30-11]
- Imprinted gene expression corresponds to parental allele-specific DNA CpG methylation and chromatin composition. Histone tail covalent modifications have been extensively studied, but it is not known whether modification...
- The Calcium-Dependent Interaction between S100B and the Mitochondrial AAA ATPase ATAD3A and the Role of This Complex in the Cytoplasmic Processing of ATAD3A
[作者:Gilquin, B; Cannon, BR; Hubstenberger, A; Moulouel, B; Falk, E; Merle, N; Assard, N; Kieffer, S; Rousseau, D; Wilder, PT; Weber, DJ; Baudier, J,期刊:Molecular and Cellular Biology, 页码:2724-2736 , 文章类型: Article,,卷期:2010年30-11]
- S100 proteins comprise a multigene family of EF-hand calcium binding proteins that engage in multiple functions in response to cellular stress. In one case, the S100B protein has been implicated in oligodendrocyte progen...
- Disruption of CK2 beta in Embryonic Neural Stem Cells Compromises Proliferation and Oligodendrogenesis in the Mouse Telencephalon
[作者:Huillard, E; Ziercher, L; Blond, O; Wong, M; Deloulme, JC; Souchelnytskyi, S; Baudier, J; Cochet, C; Buchou, T,期刊:Molecular and Cellular Biology, 页码:2737-2749 , 文章类型: Article,,卷期:2010年30-11]
- Genetic programs that govern neural stem/progenitor cell (NSC) proliferation and differentiation are dependent on extracellular cues and a network of transcription factors, which can be regulated posttranslationally by p...
- Arginine Methylation Controls the Subcellular Localization and Functions of the Oncoprotein Splicing Factor SF2/ASF
[作者:Sinha, R; Allemand, E; Zhang, Z; Karni, R; Myers, MP; Krainer, AR,期刊:Molecular and Cellular Biology, 页码:2762-2774 , 文章类型: Article,,卷期:2010年30-11]
- Alternative splicing and posttranslational modifications (PTMs) are major sources of protein diversity in eukaryotic proteomes. The SR protein SF2/ASF is an oncoprotein that functions in pre-mRNA splicing, with additiona...
- Targeted Deletion of Capn4 in Cells of the Chondrocyte Lineage Impairs Chondrocyte Proliferation and Differentiation
[作者:Kashiwagi, A; Schipani, E; Fein, MJ; Greer, PA; Shimada, M,期刊:Molecular and Cellular Biology, 页码:2799-2810 , 文章类型: Article,,卷期:2010年30-11]
- Calpains are calcium-dependent intracellular cysteine proteases, which include ubiquitously expressed mu- and m-calpains. Both calpains are heterodimers consisting of a large catalytic subunit and a small regulatory subu...
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