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  • The Ras Effector RASSF2 Controls the PAR-4 Tumor Suppressor
    [作者:Donninger, H; Hesson, L; Vos, M; Beebe, K; Gordon, L; Sidransky, D; Liu, JW; Schlegel, T; Payne, S; Hartmann, A; Latif, F; Clark, GJ,期刊:Molecular and Cellular Biology, 页码:2608-2620 , 文章类型: Article,,卷期:2010年30-11]
  • RASSF2 is a novel proapoptotic effector of K-Ras. Inhibition of RASSF2 expression enhances the transforming effects of K-Ras, and epigenetic inactivation of RASSF2 is frequently detected in mutant Ras-containing primary ...
  • DDB2, an Essential Mediator of Premature Senescence
    [作者:Roy, N; Stoyanova, T; Dominguez-Brauer, C; Park, HJ; Bagchi, S; Raychaudhuri, P,期刊:Molecular and Cellular Biology, 页码:2681-2692 , 文章类型: Article,,卷期:2010年30-11]
  • Reactive oxygen species (ROS) is critical for premature senescence, a process significant in tumor suppression and cancer therapy. Here, we reveal a novel function of the nucleotide excision repair protein DDB2 in the ac...