- Toll-Like Receptor (TLR) 2 and TLR9 Expressed in Trigeminal Ganglia are Critical to Viral Control During Herpes Simplex Virus 1 Infection
[作者:Lima, GK; Zolini, GP; Mansur, DS; Lima, BHF; Wischhoff, U; Astigarraga, RG; Dias, MF; Silva, MDA; Bela, SR; Antonelli, LRD; Arantes, RM; Gazzinelli, RT; Bafica, A; Kroon, EG; Campos, MA,期刊:American Journal of Pathology, 页码:2433-2445 , 文章类型: Article,,卷期:2010年177-5]
- Herpes simplex virus 1 (HSV-1) is a neurotropic DNA virus that is responsible for several clinical manifestations in humans, including encephalitis. HSV-1 triggers toll-like receptors (TLRs), which elicit cytokine produc...
- Insulin-Like Growth Factor 2 Receptor Is an IFN gamma-Inducible Microglial Protein that Facilitates Intracellular HIV Replication
[作者:Suh, HS; Cosenza-Nashat, M; Choi, N; Zhao, ML; Li, JF; Pollard, JW; Jirtle, RL; Goldstein, H; Lee, SC,期刊:American Journal of Pathology, 页码:2446-2458 , 文章类型: Article,,卷期:2010年177-5]
- Insulin-like growth factor 2 receptor (IGF2R), also known as cation-independent mannose 6-phosphate (M6P) receptor, is a transmembrane glycoprotein localized in the trans-Golgi region and is involved in targeting both M6...
- Dual Roles of CD40 on Microbial Containment and the Development of Immunopathology in Response to Persistent Fungal Infection in the Lung
[作者:Chen, GH; Osterholzer, JJ; Choe, MY; McDonald, RA; Olszewski, MA; Huffnagle, GB; Toews, GB,期刊:American Journal of Pathology, 页码:2459-2471 , 文章类型: Article,,卷期:2010年177-5]
- Persistent pulmonary infection with Cryptococcus neoformans in C57BL/6 mice results in chronic inflammation that is characterized by an injurious Th2 immune response. In this study, we performed a comparative analysis of...
- The Implication of Aberrant GM-CSF Expression in Decidual Cells in the Pathogenesis of Preeclampsia
[作者:Huang, SJ; Zenclussen, AC; Chen, CP; Basar, M; Yang, H; Arcuri, F; Li, M; Kocamaz, E; Buchwalder, L; Rahman, M; Kayisli, U; Schatz, F; Toti, P; Lockwood, CJ,期刊:American Journal of Pathology, 页码:2472-2482 , 文章类型: Article,,卷期:2010年177-5]
- Preeclampsia is characterized by an exaggerated systemic inflammatory state as well as shallow placentation. In the decidual implantation site, preeclampsia is accompanied by an excessive number of both macrophages and d...
- Absence of High-Risk Human Papillomavirus (HPV) Detection in Endocervical Adenocarcinoma with Gastric Morphology and Phenotype
[作者:Kusanagi, Y; Kojima, A; Mikami, Y; Kiyokawa, T; Sudo, T; Yamaguchi, S; Nishimura, R,期刊:American Journal of Pathology, 页码:2169-2175 , 文章类型: Article,,卷期:2010年177-5]
- A subset of endocervical-type mucinous adenocarcinomas (ACs) of the uterine cervix exhibit a gastric phenotype and morphology, as reported in cases of minimal deviation AC in which the presence of human papillomavirus (H...
- CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia
[作者:van der Windt, GJW; Florquin, S; de Vos, AF; van't Veer, C; Queiroz, KCS; Liang, JR; Jiang, DH; Noble, PW; van der Poll, T,期刊:American Journal of Pathology, 页码:2483-2494 , 文章类型: Article,,卷期:2010年177-5]
- Klebsiella pneumoniae is a frequently isolated causative pathogen in respiratory tract infections. CD44 is a transmembrane adhesion molecule that has been implicated in several immunological processes. To determine the r...
- Olfactomedin-4 Regulation by Estrogen in the Human Endometrium Requires Epidermal Growth Factor Signaling
[作者:Dassen, H; Punyadeera, C; Delvoux, B; Schulkens, I; Marchetti, C; Kamps, R; Klomp, J; Dijcks, F; de Goeij, A; D'Hooghe, T; Kyama, C; Ederveen, A; Dunselman, G; Groothuis, P; Romano, A,期刊:American Journal of Pathology, 页码:2495-2508 , 文章类型: Article,,卷期:2010年177-5]
- Olfactomedin-4 (OLFM-4) is an extracellular matrix protein that is highly expressed in human endometrium. We have examined the regulation and function of OLFM-4 in normal endometrium and in cases of endometriosis and end...
- An Omega-3 Fatty Acid-Enriched Diet Prevents Skeletal Muscle Lesions in a Hamster Model of Dystrophy
[作者:Fiaccavento, R; Carotenuto, F; Vecchini, A; Binaglia, L; Forte, G; Capucci, E; Maccari, AM; Minieri, M; Di Nardo, P,期刊:American Journal of Pathology, 页码:2176-2184 , 文章类型: Article,,卷期:2010年177-5]
- Currently, despite well-known mutational causes, a universal treatment for neuromuscular disorders is still lacking, and current therapeutic efforts are mainly restricted to symptomatic treatments. In the present study, ...
- Highly Pathogenic Avian Influenza Virus H7N7 Isolated From a Fatal Human Case Causes Respiratory Disease in Cats but Does Not Spread Systemically
[作者:van Riel, D; Rimmelzwaan, GF; van Amerongen, G; Osterhaus, ADME; Kuiken, T,期刊:American Journal of Pathology, 页码:2185-2190 , 文章类型: Article,,卷期:2010年177-5]
- Highly pathogenic avian influenza viruses (HPAIV) of the 115 and H7 subtypes primarily infect poultry but are occasionally transmitted to humans and other mammalian species, often causing severe disease. Previously we ha...
- Cotinine Exposure Increases Fallopian Tube PROKR1 Expression via Nicotinic AChR alpha-7 A Potential Mechanism Explaining the Link between Smoking and Tubal Ectopic Pregnancy
[作者:Shaw, JLV; Oliver, E; Lee, KF; Entrican, G; Jabbour, HN; Critchley, HOD; Horne, AW,期刊:American Journal of Pathology, 页码:2509-2515 , 文章类型: Article,,卷期:2010年177-5]
- Tubal ectopic pregnancy (EP) is the most common cause of maternal mortality in the first trimester of pregnancy; however, its etiology is uncertain. In EP, embryo retention within the Fallopian tube (FT) is thought to be...
- Enamel Protein Regulation and Dental and Periodontal Physiopathology in Msx2 Mutant Mice
[作者:Molla, M; Descroix, V; Aioub, M; Simon, S; Castaneda, B; Hotton, D; Bolanos, A; Simon, Y; Lezot, F; Goubin, G; Berdal, A,期刊:American Journal of Pathology, 页码:2516-2526 , 文章类型: Article,,卷期:2010年177-5]
- Signaling pathways that underlie postnatal dental and periodontal physiopathology are less studied than those of early tooth development. Members of the muscle segment homeobox gene (Msx) family encode homeoproteins that...
- Collagen XIII Induced in Vascular Endothelium Mediates alpha 1 beta 1 Integrin-Dependent Transmigration of Monocytes in Renal Fibrosis
[作者:Dennis, J; Meehan, DT; Delimont, D; Zallocchi, M; Perry, GA; O'Brien, S; Tu, HM; Pihlajaniemi, T; Cosgrove, D,期刊:American Journal of Pathology, 页码:2527-2540 , 文章类型: Article,,卷期:2010年177-5]
- Alport syndrome is a common hereditary basement membrane disorder caused by mutations in the collagen IV alpha 3, alpha 4, or alpha 5 genes that results in progressive glomerular and interstitial renal disease. Interstit...
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