- Histidine-Rich Glycoprotein Modulates the Anti-Angiogenic Effects of Vasculostatin
[作者:Klenotic, PA; Huang, P; Palomo, J; Kaur, B; Van Meir, EG; Vogelbaum, MA; Febbraio, M; Gladson, CL; Silverstein, RL,期刊:American Journal of Pathology, 页码:2039-2050 , 文章类型: Article,,卷期:2010年176-4]
- Brain angiogenesis inhibitor 1 (BAI1) is a transmembrane protein expressed on glial cells within the brain. Its expression is dramatically down-regulated in many glioblastomas, consistent with its functional ability to i...
- Elusive Identities and Overlapping Phenotypes of Proangiogenic Myeloid Cells in Tumors
[作者:Coffelt, SB; Lewis, CE; Naldini, L; Brown, JM; Ferrara, N; De Palma, M,期刊:American Journal of Pathology, 页码:1564-1576 , 文章类型: Review,,卷期:2010年176-4]
- It is now established that bone marrow-derived myeloid cells regulate tumor angiogenesis. This was originally inferred from studies of human tumor biopsies in which a positive correlation was seen between the number of t...
- Transglutaminase1 Preferred Substrate Peptide K5 Is an Efficient Tool in Diagnosis of Lamellar Ichthyosis
[作者:Akiyama, M; Sakai, K; Yanagi, T; Fukushima, S; Ihn, H; Hitomi, K; Shimizu, H,期刊:American Journal of Pathology, 页码:1592-1599 , 文章类型: Article,,卷期:2010年176-4]
- Lamellar ichthyosis (LI) is a genetically heterogeneous, severe genodermatosis showing widespread hyperkeratosis of the skin. Transglutaminase 1 (TGase1) deficiency by TGase1 gene (TGM1) mutations is the most prevalent c...
- Removal of Toxoplasma gondii Cysts from the Brain by Perforin-Mediated Activity of CD8(+) T Cells
[作者:Suzuki, Y; Wang, XS; Jortner, BS; Payne, L; Ni, YY; Michie, SA; Xu, BH; Kudo, T; Perkins, S,期刊:American Journal of Pathology, 页码:1607-1613 , 文章类型: Article,,卷期:2010年176-4]
- Chronic infection with Toxoplasma gondii is one of the most common parasitic infections in humans. Formation of tissue cysts is the basis of persistence of the parasite in infected hosts, and this cyst stage has generall...
- Seasonal and Pandemic Human Influenza Viruses Attach Better to Human Upper Respiratory Tract Epithelium than Avian Influenza Viruses
[作者:van Riel, D; den Bakker, MA; Leijten, LME; Chutinimitkul, S; Munster, VJ; de Wit, E; Rimmelzwaan, GF; Fouchier, RAM; Osterhaus, ADME; Kuiken, T,期刊:American Journal of Pathology, 页码:1614-1618 , 文章类型: Article,,卷期:2010年176-4]
- Influenza viruses vary markedly in their efficiency of human-to-human transmission. This variation has been speculated to be determined in part by the tropism of influenza virus for the human upper respiratory tract. To ...
- Adriamycin Nephropathy A Failure of Endothelial Progenitor Cell-Induced Repair
[作者:Yasuda, K; Park, HC; Ratliff, B; Addabbo, F; Hatzopoulos, AK; Chander, P; Goligorsky, MS,期刊:American Journal of Pathology, 页码:1685-1695 , 文章类型: Article,,卷期:2010年176-4]
- Adriamycin-associated nephropathy (AAN) remains poorly understood. We hypothesized that adriamycin affects endothelial progenitor cells (EPCs), leading to impaired regeneration. We analyzed renal hematopoietic stem cells...
- Intragraft Expression of the IL-10 Gene Is Up-Regulated in Renal Protocol Biopsies with Early Interstitial Fibrosis, Tubular Atrophy, and Subclinical Rejection
[作者:Hueso, M; Navarro, E; Moreso, F; O'Valle, F; Perez-Riba, M; del Moral, RG; Grinyo, JM; Seron, D,期刊:American Journal of Pathology, 页码:1696-1704 , 文章类型: Article,,卷期:2010年176-4]
- Grafts with subclinical rejection associated with interstitial fibrosis and tubular atrophy (SCR+IF/TA) show poorer survival than grafts with subclinical rejection without IF/TA (SCR). Aiming to detect differences among ...
- Effects of CXCR4 Gene Transfer on Cardiac Function After Ischemia-Reperfusion Injury
[作者:Chen, JQ; Chemaly, E; Liang, LF; Kho, C; Lee, A; Park, J; Altman, P; Schecter, AD; Hajjar, RJ; Tarzami, ST,期刊:American Journal of Pathology, 页码:1705-1715 , 文章类型: Article,,卷期:2010年176-4]
- Acute coronary occlusion is the leading cause of death in the Western world. There is an unmet need for the development of treatments to limit the extent of myocardial infarction (MI) during the acute phase of occlusion....
- Tim3 Is Upregulated and Protective in Nephrotoxic Serum Nephritis
[作者:Schroll, A; Eller, K; Huber, JM; Theurl, IM; Wolf, AM; Weiss, G; Rosenkranz, AR,期刊:American Journal of Pathology, 页码:1716-1724 , 文章类型: Article,,卷期:2010年176-4]
- T cell immunoglobulin and mucin protein-3 (Tim3) is mainly expressed on the cell surface of T-helper lymphocytes (T-H) that negatively regulates T-H-type 1 (T-H-1) responses. Because blockade of Tim3 aggravates disease a...
- Hypoxic Regulation of Nucleus Pulposus Cell Survival From Niche to Notch
[作者:Risbud, MV; Schipani, E; Shapiro, IM,期刊:American Journal of Pathology, 页码:1577-1583 , 文章类型: Review,,卷期:2010年176-4]
- This minireview examines the role of hypoxia, and hypoxia inducible factors (HIF-1 and HIF-2), in regulating the metabolism, function, and fate of cells of the nucleus pulposus in the intervertebral disk. We focus on the...
- Bone Marrow-Derived Cells Contribute to Fibrosis in the Chronically Failing Heart
[作者:Chu, PY; Mariani, J; Finch, S; McMullen, JR; Sadoshima, J; Marshall, T; Kaye, DM,期刊:American Journal of Pathology, 页码:1735-1742 , 文章类型: Article,,卷期:2010年176-4]
- Cardiac fibrosis contributes significantly to the phenotype of the chronically failing heart. It is not clear whether in this setting the fibrosis is contributed by native cardiac fibroblasts or alternatively by recruitm...
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