- The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720
[作者:Aronin, CEP; Shin, SJ; Naden, KB; Rios, PD; Sefcik, LS; Zawodny, SR; Bagayoko, ND; Cui, QJ; Khan, Y; Botchwey, EA,期刊:BIOMATERIALS, 页码:6417-6424 , 文章类型: Article,,卷期:2010年31-25]
- Poor vascularization coupled with mechanical instability is the leading cause of post-operative complications and poor functional prognosis of massive bone allografts. To address this limitation, we designed a novel cont...
- CD47-dependent molecular mechanisms of blood outgrowth endothelial cell attachment on cholesterol-modified polyurethane
[作者:Ueda, M; Alferiev, IS; Simons, SB; Hebbel, RP; Levy, RJ; Stachelek, SJ,期刊:BIOMATERIALS, 页码:6394-6399 , 文章类型: Article,,卷期:2010年31-25]
- We previously showed that blood outgrowth endothelial cells (BOECs) had a high affinity for polyurethane (PU) covalently configured with cholesterol residues (PU-Chol). However, the molecular mechanisms responsible for t...
- The quantification of single cell adhesion on functionalized surfaces for cell sheet engineering
[作者:Weder, G; Guillaume-Gentil, O; Matthey, N; Montagne, F; Heinzelmann, H; Voros, J; Liley, M,期刊:BIOMATERIALS, 页码:6436-6443 , 文章类型: Article,,卷期:2010年31-25]
- The use of force spectroscopy to measure and quantify the forces involved in the adhesion of 3T3 fibroblasts to different chemically functionalized surfaces has been investigated. Cells were grown on glass surfaces as we...
- Epoxy-amine synthesised hydrogel scaffolds for soft-tissue engineering
[作者:Hamid, ZAA; Blencowe, A; Ozcelik, B; Palmer, JA; Stevens, GW; Abberton, KM; Morrison, WA; Penington, AJ; Qiao, GG,期刊:BIOMATERIALS, 页码:6454-6467 , 文章类型: Article,,卷期:2010年31-25]
- Highly porous and biodegradable hydrogels based on poly(ethylene glycol) (PEG) and cystamine (Cys) were fabricated using epoxy-amine chemistry and investigated as scaffolds for soft-tissue engineering. Whereas the applic...
- Functionalization of matrices by cyclically stretched osteoblasts through matrix targeting of VEGF
[作者:Faure, C; Vico, L; Tracqui, P; Laroche, N; Linossier, MT; Rattner, A; Guignandon, A,期刊:BIOMATERIALS, 页码:6477-6484 , 文章类型: Article,,卷期:2010年31-25]
- Vascular endothelial growth factor A (VEGF) plays a central role in load-induced bone gain. We previously showed that increasing cyclic stretch frequency from 0.05 to 5 Hz induce parallel increased in entrapment of VEGF ...
- Effect of functionalized polycaprolactone on the behaviour of murine preosteoblasts
[作者:Drevelle, O; Bergeron, E; Senta, H; Lauzon, MA; Roux, S; Grenier, G; Faucheux, N,期刊:BIOMATERIALS, 页码:6468-6476 , 文章类型: Article,,卷期:2010年31-25]
- The efficiency of biomaterials used in bone repair depends greatly on their ability to interact with bone cells. Hence, we have functionalized polycaprolactone (PCL) films by peptides derived from the bone sialoprotein c...
- The role of pharmacologically active microcarriers releasing TGF-beta 3 in cartilage formation in vivo by mesenchymal stem cells
[作者:Bouffi, C; Thomas, O; Bony, C; Giteau, A; Venier-Julienne, MC; Jorgensen, C; Montero-Menei, C; Noel, D,期刊:BIOMATERIALS, 页码:6485-6493 , 文章类型: Article,,卷期:2010年31-25]
- Cartilage engineering using mesenchymal stem cells (MSC) will require the use of a scaffold which will act as a support for cell adhesion keeping the cells in the cartilage defect. Optimally, a tissue engineered construc...
- Heparin immobilized gold nanoparticles for targeted detection and apoptotic death of metastatic cancer cells
[作者:Lee, K; Lee, H; Bae, KH; Park, TG,期刊:BIOMATERIALS, 页码:6530-6536 , 文章类型: Article,,卷期:2010年31-25]
- In the present study, heparin immobilized, multifunctional gold nanoparticles (AuNPs) were developed as a new class of theragnostic nanomaterials for metastatic cancer cell imaging and apoptosis. AuNPs were surface modif...
- Block-copolymer-stabilized iodinated emulsions for use as CT contrast agents
[作者:de Vries, A; Custers, E; Lub, J; van den Bosch, S; Nicolay, K; Grull, H,期刊:BIOMATERIALS, 页码:6537-6544 , 文章类型: Article,,卷期:2010年31-25]
- The objective of this study was to develop radiopaque iodinated emulsions for use as CT blood pool contrast agents. Three hydrophobic iodinated oils were synthesized based on the 2,3,5-triiodobenzoate moiety and formulat...
- The down regulation of target genes by photo activated DNA nanoscissors
[作者:Tsai, TL; Shieh, DB; Yeh, CS; Tzeng, Y; Htet, K; Chuang, KS; Hwu, JR; Su, WC,期刊:BIOMATERIALS, 页码:6545-6554 , 文章类型: Article,,卷期:2010年31-25]
- An artificial, targeted, light-activated nanoscissor (ATLANS) was developed for precision photonic cleavage of DNA at selectable target sequences. The ATLANS is comprised of nanoparticle core and a monolayer of hydrazone...
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