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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Functional Association of the Microprocessor Complex with the Spliceosome [作者：Kataoka, N; Fujita, M; Ohno, M,期刊：Molecular and Cellular Biology, 页码：3243-3254 , 文章类型： Article，,卷期：2009年29-12] The majority of human microRNAs (miRNAs) are located in the introns of other genes (A. Rodriguez, S. Griffiths-Jones, J. L. Ashurst, and A. Bradley, Genome Res. 14: 1902-1910, 2004). Based on the discovery that artificia... A Novel Mechanism of Antagonism between ATP-Dependent Chromatin Remodeling Complexes Regulates RNR3 Expression [作者：Tomar, RS; Psathas, JN; Zhang, HS; Zhang, ZJ; Reese, JC,期刊：Molecular and Cellular Biology, 页码：3255-3265 , 文章类型： Article，,卷期：2009年29-12] Gene expression depends upon the antagonistic actions of chromatin remodeling complexes. While this has been studied extensively for the enzymes that covalently modify the tails of histones, the mechanism of how ATP-depe... Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo [作者：Juric, V; Chen, CC; Lau, LF,期刊：Molecular and Cellular Biology, 页码：3266-3279 , 文章类型： Article，,卷期：2009年29-12] Although Fas ligand (FasL) is primarily expressed by lymphoid cells, its receptor Fas (CD95/Apo-1) is broadly expressed in numerous nonlymphoid tissues and can mediate apoptosis of parenchymal cells upon injury and in... Cyclin T2 Is Essential for Mouse Embryogenesis [作者：Kohoutek, J; Li, QT; Blazek, D; Luo, ZP; Jiang, HM; Peterlin, BM,期刊：Molecular and Cellular Biology, 页码：3280-3285 , 文章类型： Article，,卷期：2009年29-12] The positive transcription elongation factor b (P-TEFb) is essential for the elongation of transcription and cotranscriptional processing by RNA polymerase II. In mammals, it contains predominantly the C-type cyclin cycl... All-trans-Retinoic Acid Represses Obesity and Insulin Resistance by Activating both Peroxisome Proliferation-Activated Receptor beta/delta and Retinoic Acid Receptor [作者：Berry, DC; Noy, N,期刊：Molecular and Cellular Biology, 页码：3286-3296 , 文章类型： Article，,卷期：2009年29-12] Many biological activities of all-trans-retinoic acid (RA) are mediated by the ligand-activated transcription factors termed retinoic acid receptors (RARs), but this hormone can also activate the nuclear receptor peroxis... Phospholipase D1 Regulates Lymphocyte Adhesion via Upregulation of Rap1 at the Plasma Membrane [作者：Mor, A; Wynne, JP; Ahearn, IM; Dustin, ML; Du, GW; Philips, MR,期刊：Molecular and Cellular Biology, 页码：3297-3306 , 文章类型： Article，,卷期：2009年29-12] Rap1 is a small GTPase that modulates adhesion of T cells by regulating inside-out signaling through LFA-1. The bulk of Rap1 is expressed in a GDP-bound state on intracellular vesicles. Exocytosis of these vesicles deliv... Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity [作者：Kim, HC; Huibregtse, JM,期刊：Molecular and Cellular Biology, 页码：3307-3318 , 文章类型： Article，,卷期：2009年29-12] Polyubiquitination can mediate several different biochemical functions, determined in part by which lysine of ubiquitin is used to link the polyubiquitin chain. Among the HECT domain ubiquitin ligases, some, such as huma... A Naturally Occurring HER2 Carboxy-Terminal Fragment Promotes Mammary Tumor Growth and Metastasis [作者：Pedersen, K; Angelini, PD; Laos, S; Bach-Faig, A; Cunningham, MP; Ferrer-Ramon, C; Luque-Garcia, A; Garcia-Castillo, J; Parra-Palau, JL; Scaltriti, M; Cajal, SRY; Baselga, J; Arribas, J,期刊：Molecular and Cellular Biology, 页码：3319-3331 , 文章类型： Article，,卷期：2009年29-12] HER2 is a tyrosine kinase receptor causally involved in cancer. A subgroup of breast cancer patients with particularly poor clinical outcomes expresses a heterogeneous collection of HER2 carboxy-terminal fragments (CTFs)... Cell Density-Dependent Inhibition of Epidermal Growth Factor Receptor Signaling by p38 alpha Mitogen-Activated Protein Kinase via Sprouty2 Downregulation [作者：Swat, A; Dolado, I; Rojas, JM; Nebreda, AR,期刊：Molecular and Cellular Biology, 页码：3332-3343 , 文章类型： Article，,卷期：2009年29-12] Contact inhibition is a fundamental process in multicellular organisms aimed at inhibiting proliferation at high cellular densities through poorly characterized intracellular signals, despite availability of growth facto... Human DNA Polymerase eta Is Required for Common Fragile Site Stability during Unperturbed DNA Replication [作者：Rey, L; Sidorova, JM; Puget, N; Boudsocq, F; Biard, DSF; Monnat, RJ; Cazaux, C; Hoffmann, JS,期刊：Molecular and Cellular Biology, 页码：3344-3354 , 文章类型： Article，,卷期：2009年29-12] Human DNA polymerase eta (Pol eta) modulates susceptibility to skin cancer by promoting translesion DNA synthesis (TLS) past sunlight-induced cyclobutane pyrimidine dimers. Despite its well-established role in TLS synthe... Direct Interaction between Myocyte Enhancer Factor 2 (MEF2) and Protein Phosphatase 1 alpha Represses MEF2-Dependent Gene Expression [作者：Perry, RLS; Yang, C; Soora, N; Salma, J; Marback, M; Naghibi, L; Ilyas, H; Chan, J; Gordon, JW; McDermott, JC,期刊：Molecular and Cellular Biology, 页码：3355-3366 , 文章类型： Article，,卷期：2009年29-12] The myocyte enhancer factor 2 (MEF2) transcription factors play important roles in neuronal, cardiac, and skeletal muscle tissues. MEF2 serves as a nuclear sensor, integrating signals from several signaling cascades thro... Regulation of Jak2 Function by Phosphorylation of Tyr(317) and Tyr(637) during Cytokine Signaling [作者：Robertson, SA; Koleva, RI; Argetsinger, LS; Carter-Su, C; Marto, JA; Feener, EP; Myers, MG,期刊：Molecular and Cellular Biology, 页码：3367-3378 , 文章类型： Article，,卷期：2009年29-12] Jak2, the cognate tyrosine kinase for numerous cytokine receptors, undergoes multisite phosphorylation during cytokine stimulation. To understand the role of phosphorylation in Jak2 regulation, we used mass spectrometry ... Extracellular Signal-Regulated Kinase 2-Dependent Phosphorylation Induces Cytoplasmic Localization and Degradation of p21(Cip1) [作者：Hwang, CY; Lee, C; Kwon, KS,期刊：Molecular and Cellular Biology, 页码：3379-3389 , 文章类型： Article，,卷期：2009年29-12] p21(Cip1) is an inhibitor of cell cycle progression that promotes G(1)-phase arrest by direct binding to cycl-independent kinase and proliferating cell nuclear antigen. Here we demonstrate that mitogenic stimuli, such as... The Cell Surface Receptor Tartan Is a Potential In Vivo Substrate for the Receptor Tyrosine Phosphatase Ptp52F [作者：Bugga, L; Ratnaparkhi, A; Zinn, K,期刊：Molecular and Cellular Biology, 页码：3390-3400 , 文章类型： Article，,卷期：2009年29-12] Receptor-linked protein-tyrosine phosphatases (RPTPs) are essential regulators of axon guidance and synaptogenesis in Drosophila, but the signaling pathways in which they function are poorly defined. We identified the ce... Ubiquitin-Regulated Recruitment of I kappa B Kinase e to the MAVS Interferon Signaling Adapter [作者：Paz, S; Vilasco, M; Arguello, M; Sun, Q; Lacoste, J; Nguyen, TLA; Zhao, TJ; Shestakova, EA; Zaari, S; Bibeau-Poirier, A; Servant, MJ; Lin, RT; Meurs, EF; Hiscott, J,期刊：Molecular and Cellular Biology, 页码：3401-3412 , 文章类型： Article，,卷期：2009年29-12] Induction of the antiviral interferon response is initiated upon recognition of viral RNA structures by the RIG-I or Mda-5 DEX(D/H) helicases. A complex signaling cascade then converges at the mitochondrial adapter MAVS,... Coactivator Function Defines the Active Estrogen Receptor Alpha Cistrome [作者：Lupien, M; Eeckhoute, J; Meyer, CA; Krum, SA; Rhodes, DR; Liu, XS; Brown, M,期刊：Molecular and Cellular Biology, 页码：3413-3423 , 文章类型： Article，,卷期：2009年29-12] Proper activation of transcriptional networks in complex organisms is central to the response to stimuli. We demonstrate that the selective activation of a subset of the estrogen receptor alpha (ER alpha) cistrome in MCF...