- Taking Charge: Feeding Malaria via Anion Channels
[作者：Ekland, EH; Akabas, MH; Fidock, DA,期刊：Cell, 页码：645-647 , 文章类型： Editorial Material，,卷期：2011年145-5]
- The human malaria parasite Plasmodium falciparum increases red blood cell membrane permeability during infection to allow for import of nutrients and other solutes. Nguitragool et al. (2011) have now identified parasite-...
- PK-M2 Makes Cells Sweeter on HIF1
[作者：Tennant, DA,期刊：Cell, 页码：647-649 , 文章类型： Editorial Material，,卷期：2011年145-5]
- The transcription factor hypoxia-inducible factor 1 (HIF1) facilitates the induction of enzymes necessary for anaerobic glycolysis. Luo et al. (2011) now identify pyruvate kinase (PK)-M2 as an intriguing new interacting ...
- Malaria Parasite clag3 Genes Determine Channel-Mediated Nutrient Uptake by Infected Red Blood Cells
[作者：Nguitragool, W; Bokhari, AAB; Pillai, AD; Rayavara, K; Sharma, P; Turpin, B; Aravind, L; Desai, SA,期刊：Cell, 页码：665-677 , 文章类型： Article，,卷期：2011年145-5]
- Development of malaria parasites within vertebrate erythrocytes requires nutrient uptake at the host cell membrane. The plasmodial surface anion channel (PSAC) mediates this transport and is an antimalarial target, but i...
- Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions
[作者：Ruthenburg, AJ; Li, HT; Milne, TA; Dewell, S; McGinty, RK; Yuen, M; Ueberheide, B; Dou, YL; Muir, TW; Patel, DJ; Allis, CD,期刊：Cell, 页码：692-706 , 文章类型： Article，,卷期：2011年145-5]
- Little is known about how combinations of histone marks are interpreted at the level of nucleosomes. The second PHD finger of human BPTF is known to specifically recognize histone H3 when methylated on lysine 4 (H3K4me2/...
- Maternal Epigenetic Pathways Control Parental Contributions to Arabidopsis Early Embryogenesis
[作者：Autran, D; Baroux, C; Raissig, MT; Lenormand, T; Wittig, M; Grob, S; Steimer, A; Barann, M; Klostermeier, UC; Leblanc, O; Vielle-Calzada, JP; Rosenstiel, P; Grimanelli, D; Grossniklaus, U,期刊：Cell, 页码：707-719 , 文章类型： Article，,卷期：2011年145-5]
- Defining the contributions and interactions of paternal and maternal genomes during embryo development is critical to understand the fundamental processes involved in hybrid vigor, hybrid sterility, and reproductive isol...
- An Intercellular Heme-Trafficking Protein Delivers Maternal Heme to the Embryo during Development in C. elegans
[作者：Chen, CY; Samuel, TK; Sinclair, J; Dailey, HA; Hamza, I,期刊：Cell, 页码：720-731 , 文章类型： Article，,卷期：2011年145-5]
- Extracellular free heme can intercalate into membranes and promote damage to cellular macromolecules. Thus it is likely that specific intercellular pathways exist for the directed transport, trafficking, and delivery of ...
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
[作者：Luo, WB; Hu, HX; Chang, R; Zhong, J; Knabel, M; O'Meally, R; Cole, RN; Pandey, A; Semenza, GL,期刊：Cell, 页码：732-744 , 文章类型： Article，,卷期：2011年145-5]
- The pyruvate kinase isoforms PKM1 and PKM2 are alternatively spliced products of the PKM2 gene. PKM2, but not PKM1, alters glucose metabolism in cancer cells and contributes to tumorigenesis by mechanisms that are not ex...
- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
[作者：Elinav, E; Strowig, T; Kau, AL; Henao-Mejia, J; Thaiss, CA; Booth, CJ; Peaper, DR; Bertin, J; Eisenbarth, SC; Gordon, JI; Flavell, RA,期刊：Cell, 页码：745-757 , 文章类型： Article，,卷期：2011年145-5]
- Inflammasomes are multiprotein complexes that function as sensors of endogenous or exogenous damage-associated molecular patterns. Here, we show that deficiency of NLRP6 in mouse colonic epithelial cells results in reduc...
- Enhanced Polyubiquitination of Shank3 and NMDA Receptor in a Mouse Model of Autism
[作者：Bangash, MA; Park, JM; Melnikova, T; Wang, DH; Jeon, SK; Lee, D; Syeda, S; Kim, J; Kouser, M; Schwartz, J; Cui, YY; Zhao, X; Speed, HE; Kee, SE; Tu, JC; Hu, JH; Petralia, RS; Linden, DJ; Powell, CM; Savonenko, A; Xiao, B; Worley, PF,期刊：Cell, 页码：758-772 , 文章类型： Article，,卷期：2011年145-5]
- We have created a mouse genetic model that mimics a human mutation of Shank3 that deletes the C terminus and is associated with autism. Expressed as a single copy [Shank3(+/Delta C) mice], Shank3 Delta C protein interact...
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