- A Breath of Fresh Air in Lung Regeneration
[作者：Beronja, S; Fuchs, E,期刊：Cell, 页码：481-483 , 文章类型： Editorial Material，,卷期：2011年147-3]
- Enhancing the ability of the lungs to regenerate following injury could revolutionize the treatment of a wide range of different diseases. In this issue, Kumar et al. (2011) and Ding et al. (2011) dissect the cellular an...
- You AhR What You Eat: Linking Diet and Immunity
[作者：Hooper, LV,期刊：Cell, 页码：486-490 , 文章类型： Editorial Material，,卷期：2011年147-3]
- The aryl hydrocarbon receptor (AhR) is responsible for the toxic effects of environmental pollutants such as dioxin, but little is known about its normal physiological functions. Li et al. (2011) now show that specific d...
- Dueling Ca(2+) Sensors in Neurotransmitter Release
[作者：Xue, MS; Giagtzoglou, N; Bellen, HJ,期刊：Cell, 页码：490-492 , 文章类型： Editorial Material，,卷期：2011年147-3]
- Ca(2+)-triggered neurotransmitter release is characterized by two kinetically distinct components: a fast synchronous phase and a slow asynchronous phase. Yao et al. (2011) now report that double C2 domain (Doc2) protein...
- Two Routes for Remembering the Past
[作者：Suzuki, W; Naya, Y,期刊：Cell, 页码：492-495 , 文章类型： Editorial Material，,卷期：2011年147-3]
- Which brain circuits underlie retrieval of distant memories? Goshen et al. (2011) use a powerful optogenetic-based approach to reveal the critical contribution of the hippocampus to remote memory retrieval. In so doing, ...
- Drop that Pipette: Science by Design
[作者：Bernstein, R,期刊：Cell, 页码：496-497 , 文章类型： Editorial Material，,卷期：2011年147-3]
- An unexpected collaboration between a synthetic biology lab at UCSF and a Palo Alto-based design firm is stirring up the way that research is conceived and conducted, by integrating innovation and "design thinking'' into...
- The Seeds of Neurodegeneration: Prion-like Spreading in ALS
[作者：Polymenidou, M; Cleveland, DW,期刊：Cell, 页码：498-508 , 文章类型： Article，,卷期：2011年147-3]
- Misfolded proteins accumulating in several neurodegenerative diseases (including Alzheimer, Parkinson, and Huntington diseases) can cause aggregation of their native counterparts through a mechanism similar to the infect...
- Molecular Mechanisms of Fear Learning and Memory
[作者：Johansen, JP; Cain, CK; Ostroff, LE; LeDoux, JE,期刊：Cell, 页码：509-524 , 文章类型： Review，,卷期：2011年147-3]
- Pavlovian fear conditioning is a particularly useful behavioral paradigm for exploring the molecular mechanisms of learning and memory because a well-defined response to a specific environmental stimulus is produced thro...
- Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection
[作者：Kumar, PA; Hu, YY; Yamamoto, Y; Hoe, NB; Wei, TS; Mu, DK; Sun, Y; Joo, LS; Dagher, R; Zielonka, EM; Wang, DY; Lim, B; Chow, VT; Crum, CP; Xian, W; McKeon, F,期刊：Cell, 页码：525-538 , 文章类型： Article，,卷期：2011年147-3]
- The extent of lung regeneration following catastrophic damage and the potential role of adult stem cells in such a process remains obscure. Sublethal infection of mice with an H1N1 influenza virus related to that of the ...
- Endothelial-Derived Angiocrine Signals Induce and Sustain Regenerative Lung Alveolarization
[作者：Ding, BS; Nolan, DJ; Guo, PP; Babazadeh, AO; Cao, ZW; Rosenwaks, Z; Crystal, RG; Simons, M; Sato, TN; Worgall, S; Shido, K; Rabbany, SY; Rafii, S,期刊：Cell, 页码：539-553 , 文章类型： Article，,卷期：2011年147-3]
- To identify pathways involved in adult lung regeneration, we employ a unilateral pneumonectomy (PNX) model that promotes regenerative alveolarization in the remaining intact lung. We show that PNX stimulates pulmonary ca...
- The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma
[作者：Oricchio, E; Nanjangud, G; Wolfe, AL; Schatz, JH; Mavrakis, KJ; Jiang, M; Liu, XP; Bruno, J; Heguy, A; Olshen, AB; Socci, ND; Teruya-Feldstein, J; Weis-Garcia, F; Tam, W; Shaknovich, R; Melnick, A; Himanen, JP; Chaganti, RSK; Wendel, HG,期刊：Cell, 页码：554-564 , 文章类型： Article，,卷期：2011年147-3]
- Insights into cancer genetics can lead to therapeutic opportunities. By cross-referencing chromosomal changes with an unbiased genetic screen we identify the ephrin receptor A7 (EPHA7) as a tumor suppressor in follicular...
- Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-beta Signaling
[作者：Mullen, AC; Orlando, DA; Newman, JJ; Loven, J; Kumar, RM; Bilodeau, S; Reddy, J; Guenther, MG; DeKoter, RP; Young, RA,期刊：Cell, 页码：565-576 , 文章类型： Article，,卷期：2011年147-3]
- Transforming growth factor beta (TGF-beta) signaling, mediated through the transcription factors Smad2 and Smad3 (Smad2/3), directs different responses in different cell types. Here we report that Smad3 co-occupies the g...
- Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration
[作者：Trompouki, E; Bowman, TV; Lawton, LN; Fan, ZP; Wu, DC; DiBiase, A; Martin, CS; Cech, JN; Sessa, AK; Leblanc, JL; Li, PL; Durand, EM; Mosimann, C; Heffner, GC; Daley, GQ; Paulson, RF; Young, RA; Zon, LI,期刊：Cell, 页码：577-589 , 文章类型： Article，,卷期：2011年147-3]
- BMP and Wnt signaling pathways control essential cellular responses through activation of the transcription factors SMAD (BMP) and TCF (Wnt). Here, we show that regeneration of hematopoietic lineages following acute inju...
- Molecular Architecture of the Transport Channel of the Nuclear Pore Complex
[作者：Solmaz, SR; Chauhan, R; Blobel, G; Melcak, I,期刊：Cell, 页码：590-602 , 文章类型： Article，,卷期：2011年147-3]
- The nuclear pore complex encloses a central channel for nucleocytoplasmic transport, which is thought to consist of three nucleoporins, Nup54, Nup58, and Nup62. However, the structure and composition of the channel are e...
- Altered Modes of Stem Cell Division Drive Adaptive Intestinal Growth
[作者：O'Brien, LE; Soliman, SS; Li, XH; Bilder, D,期刊：Cell, 页码：603-614 , 文章类型： Article，,卷期：2011年147-3]
- Throughout life, adult organs continually adapt to variable environmental factors. Adaptive mechanisms must fundamentally differ from homeostatic maintenance, but little is known about how physiological factors elicit ti...
- Arc/Arg3.1 Regulates an Endosomal Pathway Essential for Activity-Dependent beta-Amyloid Generation
[作者：Wu, J; Petralia, RS; Kurushima, H; Patel, H; Jung, MY; Volk, L; Chowdhury, S; Shepherd, JD; Dehoff, M; Li, Y; Kuhl, D; Huganir, RL; Price, DL; Scannevin, R; Troncoso, JC; Wong, PC; Worley, PF,期刊：Cell, 页码：615-628 , 文章类型： Article，,卷期：2011年147-3]
- Assemblies of beta-amyloid (A beta) peptides are pathological mediators of Alzheimer's Disease (AD) and are produced by the sequential cleavages of amyloid precursor protein (APP) by beta-secretase (BACE1) and gamma-secr...
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