- Phosphorylated filamin A regulates actin-linked caveolae dynamics
[作者：Muriel, O; Echarri, A; Hellriegel, C; Pavon, DM; Beccari, L; Del Pozo, MA,期刊：Journal of cell science, 页码：2763-2776 , 文章类型： Article，,卷期：2011年124-16]
- Caveolae are relatively stable membrane invaginations that compartmentalize signaling, regulate lipid metabolism and mediate viral entry. Caveolae are closely associated with actin fibers and internalize in response to d...
- MET signaling in GABAergic neuronal precursors of the medial ganglionic eminence restricts GDNF activity in cells that express GFR alpha 1 and a new transmembrane receptor partner
[作者：Perrinjaquet, M; Sjostrand, D; Moliner, A; Zechel, S; Lamballe, F; Maina, F; Ibanez, CF,期刊：Journal of cell science, 页码：2797-2805 , 文章类型： Article，,卷期：2011年124-16]
- GDNF (glial cell line-derived neurotrophic factor) promotes the differentiation and migration of GABAergic neuronal precursors of the medial ganglionic eminence (MGE). These functions are dependent on the GPI-anchored re...
- Peripheral lymphangiogenesis in mice depends on ectodermal connexin-26 (Gjb2)
[作者：Dicke, N; Pielensticker, N; Degen, J; Hecker, J; Tress, O; Bald, T; Gellhaus, A; Winterhager, E; Willecke, K,期刊：Journal of cell science, 页码：2806-2815 , 文章类型： Article，,卷期：2011年124-16]
- In order to study the specific function of connexin-26 (Cx26, also known as gap junction beta-2 protein; Gjb2), we generated knockin mice that expressed either a floxed lacZ reporter or, after Cre-mediated deletion, conn...
- SCF(beta TrCP) mediates stress-activated MAPK-induced Cdc25B degradation
[作者：Uchida, S; Watanabe, N; Kudo, Y; Yoshioka, K; Matsunaga, T; Ishizaka, Y; Nakagama, H; Poon, RYC; Yamashita, K,期刊：Journal of cell science, 页码：2816-2825 , 文章类型： Article，,卷期：2011年124-16]
- Cdc25A, which is one of the three mammalian CDK-activating Cdc25 protein phosphatases (Cdc25A, B and C), is degraded through SCF(beta TrCP)-mediated ubiquitylation following genomic insult; however, the regulation of the...
- MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2
[作者：Shatseva, T; Lee, DY; Deng, ZQ; Yang, BB,期刊：Journal of cell science, 页码：2826-2836 , 文章类型： Article，,卷期：2011年124-16]
- Recent advances in the study of microRNAs indicate that they have an important role in regulating cellular activities such as proliferation, morphogenesis, apoptosis and differentiation by regulating the expression of va...
- Meiotic functions of RAD18
[作者：Inagaki, A; Sleddens-Linkels, E; Wassenaar, E; Ooms, M; van Cappellen, WA; Hoeijmakers, JHJ; Seibler, J; Vogt, TF; Shin, MK; Grootegoed, JA; Baarends, WM,期刊：Journal of cell science, 页码：2837-2850 , 文章类型： Article，,卷期：2011年124-16]
- RAD18 is an ubiquitin ligase that is involved in replication damage bypass and DNA double-strand break (DSB) repair processes in mitotic cells. Here, we investigated the testicular phenotype of Rad18-knockdown mice to de...
- A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome
[作者：Keembiyehetty, CN; Krzeslak, A; Love, DC; Hanover, JA,期刊：Journal of cell science, 页码：2851-2860 , 文章类型： Article，,卷期：2011年124-16]
- Protein-O-linked N-Acetyl-beta-D-glucosaminidase (O-GlcNAcase, OGA; also known as hexosaminidase C) participates in a nutrient-sensing, hexosamine signaling pathway by removing O-linked N-acetylglucosamine (O-GlcNAc) fro...
- The C-terminal tail of tetraspanin protein CD9 contributes to its function and molecular organization
[作者：Wang, HX; Kolesnikova, TV; Denison, C; Gygi, SP; Hemler, ME,期刊：Journal of cell science, 页码：2702-2710 , 文章类型： Article，,卷期：2011年124-16]
- Tetraspanin protein CD9 supports sperm-egg fusion, and regulates cell adhesion, motility, metastasis, proliferation and signaling. The large extracellular loop and transmembrane domains of CD9 engage in functionally impo...
- PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer
[作者：Johnson, EO; Chang, KH; de Pablo, Y; Ghosh, S; Mehta, R; Badve, S; Shah, K,期刊：Journal of cell science, 页码：2711-2722 , 文章类型： Article，,卷期：2011年124-16]
- Aurora A kinase is overexpressed in the majority of breast carcinomas. A chemical genetic approach was used to identify the malignant targets of Aurora A, which revealed pleckstrin-homology-like domain protein PHLDA1 as ...
- Genetic deletion of Cyp26b1 negatively impacts limb skeletogenesis by inhibiting chondrogenesis
[作者：Dranse, HJ; Sampaio, AV; Petkovich, M; Underhill, TM,期刊：Journal of cell science, 页码：2723-2734 , 文章类型： Article，,卷期：2011年124-16]
- Cyp26b1, a retinoic acid (RA)-metabolising enzyme, is expressed in the developing limb bud, and Cyp26b1(-/-) mice present with severe limb defects. These malformations might be attributable to an RA-induced patterning de...
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