- Tbx1 Regulates Proliferation and Differentiation of Multipotent Heart Progenitors
[作者：Chen, L; Fulcoli, FG; Tang, S; Baldini, A,期刊：Circulation Research, 页码：842-U38 , 文章类型： Review，,卷期：2009年105-9]
- Rationale: TBX1 encodes a T-box transcription factor implicated in DiGeorge syndrome, which affects the development of many organs, including the heart. Loss of Tbx1 results into hypoplasia of heart regions derived from ...
- Aldosterone-Induced Activation of Signaling Pathways Requires Activity of Angiotensin Type 1a Receptors
[作者：Lemarie, CA; Simeone, SMC; Nikonova, A; Ebrahimian, T; Deschenes, ME; Coffman, TM; Paradis, P; Schiffrin, EL,期刊：Circulation Research, 页码：852-U50 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Aldosterone has been shown to induce vascular damage, endothelial dysfunction, and myocardial fibrosis, which depend in part on activation of angiotensin II (Ang II)-mediated pathways. However, mechanisms unde...
- Concurrent Vasculogenesis and Neurogenesis From Adult Neural Stem Cells
[作者：Ii, M; Nishimura, H; Sekiguchi, H; Kamei, N; Yokoyama, A; Horii, M; Asahara, T,期刊：Circulation Research, 页码：860-U67 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Recent reports have demonstrated that signals from vascular endothelial cells are necessary for organogenesis that may precede vasculogenesis. However, the origin of these neovascular cells in regenerating tis...
- Shear Stress Regulates Angiotensin Type 1 Receptor Expression in Endothelial Cells
[作者：Ramkhelawon, B; Vilar, J; Rivas, D; Mees, B; de Crom, R; Tedgui, A; Lehoux, S,期刊：Circulation Research, 页码：869-U77 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Shear stress (SS) has an established role in atherosclerotic plaque localization, but how it exerts its protective effect is not fully understood. Objective: To test the hypothesis that SS may downregulate ang...
- Ultrastructural and Functional Remodeling of the Coupling Between Ca2+ Influx and Sarcoplasmic Reticulum Ca2+ Release in Right Atrial Myocytes From Experimental Persistent Atrial Fibrillation
[作者：Lenaerts, I; Bito, V; Heinzel, FR; Driesen, RB; Holemans, P; D'hooge, J; Heidbuchel, H; Sipido, KR; Willems, R,期刊：Circulation Research, 页码：876-U111 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Persistent atrial fibrillation (AF) has been associated with structural and electric remodeling and reduced contractile function. \ Objective: To unravel mechanisms underlying reduced sarcoplasmic reticulum (S...
- Transcriptional Upregulation of Mitochondrial Uncoupling Protein 2 Protects Against Oxidative Stress-Associated Neurogenic Hypertension
[作者：Chan, SHH; Wu, CA; Wu, KLH; Ho, YH; Chang, AYW; Chan, JYH,期刊：Circulation Research, 页码：886-U145 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Mitochondrial uncoupling proteins (UCPs) belong to a superfamily of mitochondrial anion transporters that uncouple ATP synthesis from oxidative phosphorylation and mitigates mitochondrial reactive oxygen speci...
- Insulin-Like Growth Factor Binding Protein-3 Mediates Vascular Repair by Enhancing Nitric Oxide Generation
[作者：Kielczewski, JL; Jarajapu, YPR; McFarland, EL; Cai, J; Afzal, A; Calzi, SL; Chang, KH; Lydic, T; Shaw, LC; Busik, J; Hughes, J; Cardounel, AJ; Wilson, K; Lyons, TJ; Boulton, ME; Mames, RN; Chan-Ling, T; Grant, MB,期刊：Circulation Research, 页码：897-U174 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Insulin-like growth factor binding protein (IGFBP)-3 modulates vascular development by regulating endothelial progenitor cell (EPC) behavior, specifically stimulating EPC cell migration. This study was underta...
- Periadventitial Adipose Tissue Plays a Critical Role in Vascular Remodeling
[作者：Takaoka, M; Nagata, D; Kihara, S; Shimomura, I; Kimura, Y; Tabata, Y; Saito, Y; Nagai, R; Sata, M,期刊：Circulation Research, 页码：906-U185 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Obesity is associated with a high incidence of cardiovascular complications. However, the molecular link between obesity and vascular disease is not fully understood. Most previous studies have focused on the ...
- Myeloid Differentiation Factor-88/Interleukin-1 Signaling Controls Cardiac Fibrosis and Heart Failure Progression in Inflammatory Dilated Cardiomyopathy
[作者：Blyszczuk, P; Kania, G; Dieterle, T; Marty, RR; Valaperti, A; Berthonneche, C; Pedrazzini, T; Berger, CT; Dirnhofer, S; Matter, CM; Penninger, JM; Luscher, TF; Eriksson, U,期刊：Circulation Research, 页码：912-U204 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: The myeloid differentiation factor (MyD)88/interleukin (IL)-1 axis activates self-antigen-presenting cells and promotes autoreactive CD4(+) T-cell expansion in experimental autoimmune myocarditis, a mouse mode...
- A Role of Matrix Metalloproteinase-8 in Atherosclerosis
[作者：Laxton, RC; Hu, YH; Duchene, J; Zhang, F; Zhang, ZY; Leung, KY; Xiao, QZ; Scotland, RS; Hodgkinson, CP; Smith, K; Willeit, J; Lopez-Otin, C; Simpson, IA; Kiechl, S; Ahluwalia, A; Xu, QB; Ye, S,期刊：Circulation Research, 页码：921-U231 , 文章类型： Article，,卷期：2009年105-9]
- Rationale: Atherosclerotic lesions express matrix metalloproteinase (MMP)8, which possesses proteolytic activity on matrix proteins particularly fibrillar collagens and on nonmatrix proteins such as angiotensin (Ang) I. ...
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