- Keratin gene mutations in disorders of human skin and its appendages
[作者:Chamcheu, JC; Siddiqui, IA; Syed, DN; Adhami, VM; Liovic, M; Mukhtar, H,期刊:Archives of Biochemistry and Biophysics , 页码:123-137 , 文章类型: Review,,卷期:2011年508-2]
- Keratins, the major structural protein of all epithelia are a diverse group of cytoskeletal scaffolding proteins that form intermediate filament networks, providing structural support to keratinocytes that maintain the i...
- Aquaporin-3 in keratinocytes and skin: Its role and interaction with phospholipase D2
[作者:Qin, HX; Zheng, XJ; Zhong, XF; Shetty, AK; Elias, PM; Bollag, WB,期刊:Archives of Biochemistry and Biophysics , 页码:138-143 , 文章类型: Review,,卷期:2011年508-2]
- Aquaporin 3 (AQP3) is an aquaglyceroporin that transports water and glycerol and is expressed in the epidermis, among other epithelial tissues. We have recently shown that there is an association between this glycerol ch...
- The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges
[作者:Ndiaye, M; Philippe, C; Mukhtar, H; Ahmad, N,期刊:Archives of Biochemistry and Biophysics , 页码:164-170 , 文章类型: Review,,卷期:2011年508-2]
- Resveratrol, a phytoalexin antioxidant found in red grapes, has been shown to have both chemopreventive and therapeutic effects against many diseases and disorders, including those of the skin. Studies have shown protect...
- Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by Toll-like receptor-4
[作者:Lewis, W; Simanyi, E; Li, H; Thompson, CA; Nasti, TH; Jaleel, T; Xu, H; Yusuf, N,期刊:Archives of Biochemistry and Biophysics , 页码:171-177 , 文章类型: Article,,卷期:2011年508-2]
- UVB radiation is a potent immunosuppressive agent that inhibits cell-mediated immune responses. The mechanisms by which UVB radiation influences cell-mediated immune responses have been the subject of extensive investiga...
- Role of beta-TrCP ubiquitin ligase receptor in UVB mediated responses in skin
[作者:Bhatia, N; Demmer, TA; Sharma, AK; Elcheva, I; Spiegelman, VS,期刊:Archives of Biochemistry and Biophysics , 页码:178-184 , 文章类型: Article,,卷期:2011年508-2]
- Skin cancers are the most common cancers in the United States. Exposure to UVB radiation is a major risk factor for skin cancer induction. SCF beta-TrCP E3 ubiquitin ligase has been found to be involved in cell cycle, ce...
- Structural alterations of the FAS gene in cutaneous T-cell lymphoma (CTCL)
[作者:Wu, JQ; Siddiqui, J; Nihal, M; Vonderheid, EC; Wood, GS,期刊:Archives of Biochemistry and Biophysics , 页码:185-191 , 文章类型: Article,,卷期:2011年508-2]
- FAS (TNF receptor superfamily member 6, also known as CD95) plays a major role in T-cell apoptosis and is often dysregulated in CTCL. We searched for structural alterations of the FAS gene with the potential to affect it...
- Liver kinase B1 (LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma
[作者:Byekova, YA; Herrmann, JL; Xu, JM; Elmets, CA; Athar, M,期刊:Archives of Biochemistry and Biophysics , 页码:204-211 , 文章类型: Article,,卷期:2011年508-2]
- LKB1, a known tumor suppressor, is mutated in Peutz-Jeghers Syndrome (PJS). It is responsible for the enhanced cancer risk in patients with PJS. Dysregulation of LKB1-dependent signaling also occurs in various epithelial...
- Active transport of contact allergens in human monocyte-derived dendritic cells is mediated by multidrug resistance related proteins
[作者:Skazik, C; Heise, R; Ott, H; Czaja, K; Marquardt, Y; Merk, HF; Baron, JM,期刊:Archives of Biochemistry and Biophysics , 页码:212-216 , 文章类型: Article,,卷期:2011年508-2]
- The multidrug resistance related proteins (MRPs) function as efflux transporters of a variety of large organic anions or their conjugates. In recent studies we demonstrated that antigen-presenting cells express a specifi...
- Identification of novel small molecules that inhibit protein-protein interactions between MAGE and KAP-1
[作者:Bhatia, N; Yang, B; Xiao, TZ; Peters, N; Hoffmann, MF; Longley, BJ,期刊:Archives of Biochemistry and Biophysics , 页码:217-221 , 文章类型: Article,,卷期:2011年508-2]
- The Class I MACE proteins are normally expressed only in developing germ cells but are often aberrantly expressed in malignancies, particularly melanoma, making them good therapeutic targets. MACE proteins promote tumor ...
- Interactions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes
[作者:Kedlaya, R; Kandala, G; Liu, TF; Maddodi, N; Devi, S; Setaluri, V,期刊:Archives of Biochemistry and Biophysics , 页码:227-233 , 文章类型: Article,,卷期:2011年508-2]
- By virtue of the presence of multiple protein-protein interaction and signaling domains, PDZ proteins play important roles in assembling protein complexes that participate in diverse cell biological processes. GIPC is a ...
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