- Reconstructing a solid-solid phase transformation pathway in CdSe nanosheets with associated soft ligands
[作者:Wang, ZW; Wen, XD; Hoffmann, R; Son, JS; Li, RP; Fang, CC; Smilgies, DM; Hyeon, T,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17119-17124 , 文章类型: Article,,卷期:2010年107-40]
- Integrated single-crystal-like small and wide-angle X-ray diffraction images of a CdSe nanosheet under pressure provide direct experimental evidence for the detailed pathway of transformation of the CdSe from a wurtzite ...
- Response of Colorado River runoff to dust radiative forcing in snow
[作者:Painter, TH; Deems, JS; Belnap, J; Hamlet, AF; Landry, CC; Udall, B,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17125-17130 , 文章类型: Article,,卷期:2010年107-40]
- The waters of the Colorado River serve 27 million people in seven states and two countries but are overallocated by more than 10% of the river's historical mean. Climate models project runoff losses of 7-20% from the bas...
- The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I kappa B kinase subunit IKK alpha
[作者:Gouin, E; Adib-Conquy, M; Balestrino, D; Nahori, MA; Villiers, V; Colland, F; Dramsi, S; Dussurget, O; Cossart, P,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17333-17338 , 文章类型: Article,,卷期:2010年107-40]
- Listeria monocytogenes is an intracellular pathogen responsible for severe foodborne infections. It can replicate in both phagocytic and nonphagocytic mammalian cells. The infectious process at the cellular level has bee...
- Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses
[作者:St Vincent, MR; Colpitts, CC; Ustinov, AV; Muqadas, M; Joyce, MA; Barsby, NL; Epand, RF; Epand, RM; Khramyshev, SA; Valueva, OA; Korshun, VA; Tyrrell, DLJ; Schang, LM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17339-17344 , 文章类型: Article,,卷期:2010年107-40]
- Antiviral drugs targeting viral proteins often result in prompt selection for resistance. Moreover, the number of viral targets is limited. Novel antiviral targets are therefore needed. The unique characteristics of fusi...
- Direct search for a ferromagnetic phase in a heavily overdoped nonsuperconducting copper oxide
[作者:Sonier, JE; Kaiser, CV; Pacradouni, V; Sabok-Sayr, SA; Cochrane, C; MacLaughlin, DE; Komiya, S; Hussey, NE,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17131-17134 , 文章类型: Article,,卷期:2010年107-40]
- The doping of charge carriers into the CuO2 planes of copper oxide Mott insulators causes a gradual destruction of antiferromagnetism and the emergence of high-temperature superconductivity. Optimal superconductivity is ...
- Storage of nuclear magnetization as long-lived singlet order in low magnetic field
[作者:Pileio, G; Carravetta, M; Levitt, MH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17135-17139 , 文章类型: Article,,卷期:2010年107-40]
- Hyperpolarized nuclear states provide NMR signals enhanced by many orders of magnitude, with numerous potential applications to analytical NMR, in vivo NMR, and NMR imaging. However, the lifetime of hyperpolarized magnet...
- Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis
[作者:Heaton, NS; Perera, R; Berger, KL; Khadka, S; LaCount, DJ; Kuhn, RJ; Randall, G,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17345-17350 , 文章类型: Article,,卷期:2010年107-40]
- Dengue virus (DENV) modifies cellular membranes to establish its sites of replication. Although the 3D architecture of these structures has recently been described, little is known about the cellular pathways required fo...
- Periplasmic domain of the sensor-kinase BvgS reveals a new paradigm for the Venus flytrap mechanism
[作者:Herrou, J; Bompard, C; Wintjens, R; Dupre, E; Willery, E; Villeret, V; Locht, C; Antoine, R; Jacob-Dubuisson, F,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17351-17355 , 文章类型: Article,,卷期:2010年107-40]
- Two-component sensory transduction systems control important bacterial programs. In Bordetella pertussis, expression of the virulence regulon is controlled by the unorthodox BvgAS two-component system. BvgS is the protot...
- Defining the mechanism of polymerization in the serpinopathies
[作者:Ekeowa, UI; Freeke, J; Miranda, E; Gooptu, B; Bush, MF; Perez, J; Teckman, J; Robinson, CV; Lomas, DA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17146-17151 , 文章类型: Article,,卷期:2010年107-40]
- The serpinopathies result from the ordered polymerization of mutants of members of the serine proteinase inhibitor (serpin) superfamily. These polymers are retained within the cell of synthesis where they cause a toxic g...
- Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action
[作者:Dunkle, JA; Xiong, LQ; Mankin, AS; Cate, JHD,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17152-17157 , 文章类型: Article,,卷期:2010年107-40]
- Differences between the structures of bacterial, archaeal, and eukaryotic ribosomes account for the selective action of antibiotics. Even minor variations in the structure of ribosomes of different bacterial species may ...
- Oscillatory phase coupling coordinates anatomically dispersed functional cell assemblies
[作者:Canolty, RT; Ganguly, K; Kennerley, SW; Cadieu, CF; Koepsell, K; Wallis, JD; Carmena, JM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17356-17361 , 文章类型: Article,,卷期:2010年107-40]
- Hebb proposed that neuronal cell assemblies are critical for effective perception, cognition, and action. However, evidence for brain mechanisms that coordinate multiple coactive assemblies remains lacking. Neuronal osci...
- Structural context shapes the aquaporin selectivity filter
[作者:Savage, DF; O'Connell, JD; Miercke, LJW; Finer-Moore, J; Stroud, RM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17164-17169 , 文章类型: Article,,卷期:2010年107-40]
- Aquaporins are transmembrane channels that facilitate the permeation of water and small, uncharged amphipathic molecules across cellular membranes. One distinct aquaporin subfamily contains pure water channels, whereas a...
- Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
[作者:Li, HM; Wang, BP; Wang, ZL; Guo, QX; Tabuchi, K; Hammer, RE; Sudhof, TC; Zheng, H,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:17362-17367 , 文章类型: Article,,卷期:2010年107-40]
- Amyloidogenic processing of the amyloid precursor protein (APP) generates a large secreted ectodomain fragment (APPs beta), beta-amyloid (A beta) peptides, and an APP intracellular domain (AICD). Whereas A beta is viewed...
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