- Cytotoxic Activity of New Acetoxycoumarin Derivatives in Cancer Cell Lines
[作者:Musa, MA; Badisa, VLD; Latinwo, LM; Cooperwood, J; Sinclair, A; Abdullah, A,期刊:Anticancer Research, 页码:2017-2022 , 文章类型: Article,,卷期:2011年31-6]
- Background: Coumarin and their derivatives are important and useful compounds with diverse pharmacological properties. In the present study, we evaluated the in vitro cytotoxic activity of new acetoxycoumarin derivatives...
- Characterization of the Effect of In Vivo Doxorubicin Treatment on Skeletal Muscle Function in the Rat
[作者:Hydock, DS; Lien, CY; Jensen, BT; Schneider, CM; Hayward, R,期刊:Anticancer Research, 页码:2023-2028 , 文章类型: Article,,卷期:2011年31-6]
- Doxorubicin (DOX)-induced muscle dysfunction may contribute to patient fatigue, but the nature of this myotoxicity remains unclear. The purpose of this study was to characterize the muscle function dose-response to DOX. ...
- LLL12 Inhibits Endogenous and Exogenous Interleukin-6-induced STAT3 Phosphorylation in Human Pancreatic Cancer Cells
[作者:Liu, AG; Liu, Y; Li, PK; Li, CL; Lin, JY,期刊:Anticancer Research, 页码:2029-2035 , 文章类型: Article,,卷期:2011年31-6]
- Pancreatic cancer is one of the most serious types of cancer, with a five-year survival rate at only 6%. There is a critical need to develop more effective treatments for pancreatic cancer. Growing evidence shows that ch...
- Overexpression of K-Actin Alters Growth Properties of Hepatoma Cells and Predicts Poor Postoperative Prognosis
[作者:Chang, KW; Chou, A; Lee, CC; Yeh, C; Lai, MW; Yeh, TS; Chen, TC; Liang, KH; Yeh, CT,期刊:Anticancer Research, 页码:2037-2044 , 文章类型: Article,,卷期:2011年31-6]
- Since Rho-mediated signaling can regulate liver cancer cell proliferation, amino acid sequence changes of its downstream targets, actins, might alter the properties of cell growth. Here, we investigated the function of a...
- Predicting Response to Benzamide Riboside Chemotherapy in Hepatocellular Carcinoma Using Apparent Diffusion Coefficient of Water
[作者:Babsky, AM; Ju, SH; George, B; Bennett, S; Huang, MS; Jayaram, HN; McLennan, G; Bansal, N,期刊:Anticancer Research, 页码:2045-2051 , 文章类型: Article,,卷期:2011年31-6]
- Aim: To monitor the effects of the apoptotic agent benzamide riboside (BR) on tumor volume and water apparent diffusion coefficient (ADC) in rat hepatocellular carcinoma (HCC). Materials and Methods: Water ADC of the tum...
- Identification of Differentially Expressed Proteins in Tumour Necrosis Factor-alpha-resistant and -sensitive Rat Hepatoma Cells
[作者:Kuramitsu, Y; Zhang, XL; Wang, YF; Nakamura, K,期刊:Anticancer Research, 页码:2059-2063 , 文章类型: Article,,卷期:2011年31-6]
- Background: Our earlier studies reported that ONO-4007, a synthetic lipid A analogue with low endotoxic activity, had shown much effect on tumour necrosis factor (TNF)-alpha-sensitive rat hepatoma cells, even though it h...
- The Therapeutic Effects of R8-Liposome-BCG-CWS on BBN-Induced Rat Urinary Bladder Carcinoma
[作者:Miyazaki, J; Nishiyama, H; Yano, I; Nakaya, A; Kohama, H; Kawai, K; Joraku, A; Nakamura, T; Harashima, H; Akaza, H,期刊:Anticancer Research, 页码:2065-2071 , 文章类型: Article,,卷期:2011年31-6]
- Background: The present gold standard for bladder cancer is Mycobacterium bovis bacillus Calmette-Guerin (BCG) immunotherapy, but serious side-effects are common. We previously reported that C3H/HeN mice vaccinated with ...
- Ischemic Time Impacts Biological Integrity of Phospho-proteins in PI3K/Akt, Erk/MAPK, and p38 MAPK Signaling Networks
[作者:Holzer, TR; Fulford, AD; Arkins, AM; Grondin, JM; Mundy, CW; Nasir, A; Schade, AE,期刊:Anticancer Research, 页码:2073-2081 , 文章类型: Article,,卷期:2011年31-6]
- Post-translational modifications of proteins, such as phosphorylation, are labile events dynamically regulated by opposing kinase and phosphatase activities. Preanalytical factors, such as ischemic time before fixation, ...
- Phase II Trial of Weekly Alternating Sequential BIBF 1120 and Afatinib for Advanced Colorectal Cancer
[作者:Bouche, O; Maindrault-Goebel, F; Ducreux, M; Lledo, G; Andre, T; Stopfer, P; Amellal, N; Merger, M; De Gramont, A,期刊:Anticancer Research, 页码:2271-2281 , 文章类型: Article,,卷期:2011年31-6]
- Aim: The feasibility of an alternating regimen of BIBF 1120, a potent, oral, triple angiokinase inhibitor, and afatinib (BIBW 2992), a potent ErbB family blocker, was explored in patients with advanced pretreated colorec...
- Endoglin (CD105): A Review of its Role in Angiogenesis and Tumor Diagnosis, Progression and Therapy
[作者:Nassiri, F; Cusimano, MD; Scheithauer, BW; Rotondo, F; Fazio, A; Yousef, GM; Syro, LV; Kovacs, K; Lloyd, RV,期刊:Anticancer Research, 页码:2283-2290 , 文章类型: Review,,卷期:2011年31-6]
- Endoglin (CD105) is an accessory receptor for transforming growth factor beta (TGF-beta) and its expression is up-regulated in actively proliferating endothelial cells. Endoglin has been suggested as an appropriate marke...
- Percutaneous Radiofrequency Ablation of Hepatocellular Carcinoma Compared to Percutaneous Ethanol Injection in Treatment of Cirrhotic Patients: An Italian Randomized Controlled Trial
[作者:Giorgio, A; Di Sarno, A; De Stefano, G; Scognamiglio, U; Farella, N; Mariniello, A; Esposito, V; Coppola, C; Giorgio, V,期刊:Anticancer Research, 页码:2291-2295 , 文章类型: Article,,卷期:2011年31-6]
- Aim: To compare 5-year survival of patients with a single hepatocellular carcinoma <= 3 cm randomly assigned to receive percutaneous ethanol injection or radiofrequency ablation. Patients and Methods: A total of 285 pati...
- Efficacy and Safety of Bortezomib plus Dexamethasone Therapy for Refractory or Relapsed Multiple Myeloma: Once-weekly Administration of Bortezomib may Reduce the Incidence of Gastrointestinal Adverse Events
[作者:Fukushima, T; Nakamura, T; Iwao, H; Nakajima, A; Miki, M; Sato, T; Sakai, T; Sawaki, T; Fujita, Y; Tanaka, M; Masaki, Y; Nakajima, H; Motoo, Y; Umehara, H,期刊:Anticancer Research, 页码:2297-2302 , 文章类型: Article,,卷期:2011年31-6]
- Background: To establish the clinical use of bortezomib with fewer adverse events, we retrospectively analyzed the efficacy and safety of bortezomib plus dexamethasone (BD) therapy for relapsed or refractory multiple mye...
- Expression of p53, Ki-67, E-Cadherin, N-Cadherin and TOP2A in Triple-negative Breast Cancer
[作者:Nakagawa, M; Bando, Y; Nagao, T; Morimoto, M; Takai, C; Ohnishi, T; Honda, J; Moriya, T; Izumi, K; Takahashi, M; Sasa, M; Tangoku, A,期刊:Anticancer Research, 页码:2389-2393 , 文章类型: Article,,卷期:2011年31-6]
- Background: Elucidation of the biological features of triple negative breast cancer (TNBC) is important for deciding treatment strategies. The expression of a number of biomarkers in TNBC was analyzed to elucidate those ...
- Methylenetetrahydrofolate Reductase (MTHFR) Genotype, Smoking Habit, Metastasis and Oral Cancer in Taiwan
[作者:Tsai, CW; Hsu, CF; Tsai, MH; Tsou, YA; Hua, CH; Chang, WS; Lin, CC; Bau, DT,期刊:Anticancer Research, 页码:2395-2399 , 文章类型: Article,,卷期:2011年31-6]
- The aim of this study was to evaluate the association and interaction of genotypic polymorphism in methylenetetrahydrofolate reductase (MTHFR) with smoking habits and oral cancer in Taiwan. Two well-known polymorphic var...
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