- Arf family GTP loading is activated by, and generates, positive membrane curvature
[作者:Lundmark, R; Doherty, GJ; Vallis, Y; Peter, BJ; Mcmahon, HT,期刊:Biochemical Journal, 页码:189-194 , 文章类型: Article,,卷期:2008年414-2]
- Small G-proteins belonging to the Arf (ADP-ribosylation factor) family serve as regulatory proteins for numerous cellular processes through GTP-dependent recruitment of effector molecules. In the present study we demonst...
- Assembly of a membrane receptor complex: roles of the uroplakin II prosequence in regulating uroplakin bacterial receptor oligomerization
[作者:Hu, CCA; Bachmann, T; Zhou, G; Liang, FX; Ghiso, J; Kreibich, G; Sun, TT,期刊:Biochemical Journal, 页码:195-203 , 文章类型: Article,,卷期:2008年414-2]
- The apical surface of the mammalian urothelium is almost completely covered by two-dimensional protein crystals (known Lis urothelial plaques) of hexagonally packed 16nm particles consisting of two UP (uroplakin) heterod...
- The HIV-1 p6/EIAV p9 docking site in Alix is autoinhibited as revealed by a conformation-sensitive anti-Alix monoclonal antibody
[作者:Zhou, X; Pan, SJ; Sun, L; Corvera, J; Lin, SH; Kuang, J,期刊:Biochemical Journal, 页码:215-220 , 文章类型: Article,,卷期:2008年414-2]
- Alix [ALG-2 (apoptosis-linked gene 2)-interacting protein X], a component of the endosomal sorting machinery, contains a three-dimensional docking site for HIV-I p6(Gag) or EIAV (equine infectious anaemia virus) p9(Gag),...
- Crucial role of the C-terminus of PTEN in antagonizing NEDD4-1-mediated PTEN ubiquitination and degradation
[作者:Wang, XJ; Shi, YJ; Wang, JR; Huang, GC; Jiang, XJ,期刊:Biochemical Journal, 页码:221-229 , 文章类型: Article,,卷期:2008年414-2]
- PTEN (phosphatase and tensin homologue deleted on chromosome 10), a potent tumour suppressor and multifunctional signalling protein, is under intricate regulation. In the present study, we have investigated the mechanism...
- The presence of an ER exit signal determines the protein sorting upon ER exit in yeast
[作者:Watanabe, R; Castillon, GA; Meury, A; Riezman, H,期刊:Biochemical Journal, 页码:237-245 , 文章类型: Article,,卷期:2008年414-2]
- In yeast, there are at least two vesicle populations upon ER (endoplasmic reticulum) exit, one containing Gap 1 p (general amino-acid permease) and a glycosylated alpha-factor, gp alpha F (glycosylated pro alpha-factor),...
- Identification of essential amino acid residues in a sterol 8,7-isomerase from Zea mays reveals functional homology and diversity with the isomerases of animal and fungal origin
[作者:Rahier, A; Pierre, S; Riveill, G; Karst, F,期刊:Biochemical Journal, 页码:247-259 , 文章类型: Article,,卷期:2008年414-2]
- A putative 8,7SI (sterol 8,7-isomerase) from Zea mays, termed 7m8,7SI, has been isolated from an EST (expressed sequence tag) library and subcloned into the yeast erg2 mutant lacking 8,7SI activity. Zm8,7SI restored endo...
- Critical roles of actin-interacting protein 1 in cytokinesis and chemotactic migration of mammalian cells
[作者:Kato, A; Kurita, S; Hayashi, A; Kaji, N; Ohashi, K; Mizuno, K,期刊:Biochemical Journal, 页码:261-270 , 文章类型: Article,,卷期:2008年414-2]
- Coll regulates actin filament dynamics by stimulating actin filament disassembly and plays a critical role in cytokinesis and chemotactic migration. Aip1 (actin-interacting protein 1), also called WDR1 (WID-repeat protei...
- Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid
[作者:Lloyd, MM; van Reykt, DM; Davies, MJ; Hawkins, CL,期刊:Biochemical Journal, 页码:271-280 , 文章类型: Article,,卷期:2008年414-2]
- Hypohalous acids are generated by activated leucocytes, via the formation of H2O2 and the release of peroxidase enzymes (myelo-peroxidase and eosinophil peroxidase). These species are important bactericidal agents, but H...
- A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism
[作者:Bennett, JP; Bertin, L; Moulton, B; Fairlamb, IJS; Brzozowski, AM; Walton, NJ; Grogan, G,期刊:Biochemical Journal, 页码:281-289 , 文章类型: Article,,卷期:2008年414-2]
- HCHL (hydroxycinnamoyl-CoA hydratase-lyase) catalyses the biotransformation of feruloyl-CoA to acetyl-CoA and the important flavour-fragrance compound vanillin (4-hydroxy-3-methoxy-benzaldehyde) and is exploited in whole...
- Mutation of Trp(29) of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity
[作者:Paproski, RJ; Visser, F; Zhang, J; Tackaberry, T; Damaraju, V; Baldwin, SA; Young, JD; Cass, CE,期刊:Biochemical Journal, 页码:291-300 , 文章类型: Article,,卷期:2008年414-2]
- hENT1 (human equilibrative nucleoside transporter 1) is inhibited by nanomolar concentrations of various structurally distinct coronary vasodilator drugs, including dipyridamole, dilazep, draflazine, soluflazine and NBMP...
- Contribution of Yap1 towards Saccharomyces cerevisiae adaptation to arsenic-mediated oxidative stress
[作者:Menezes, RA; Amaral, C; Batista-Nascimento, L; Santos, C; Ferreira, RB; Devaux, F; Eleutherio, ECA; Rodrigues-Pousada, C,期刊:Biochemical Journal, 页码:301-311 , 文章类型: Article,,卷期:2008年414-2]
- In the budding yeast Saccharomyces cerevisiae, arsenic detoxification involves the activation of Yap8, a member of the Yap (yeast AP-1-like) family of transcription factors, which in turn regulates ACR2 and ACR3, genes e...
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