- Redox Potential of the Primary Plastoquinone Electron Acceptor Q(A) in Photosystem II from Thermosynechococcus elongatus Determined by Spectroelectrochemistry
[作者:Shibamoto, T; Kato, Y; Sugiura, M; Watanabe, T,期刊:Biochemistry, 页码:10682-10684 , 文章类型: Article,,卷期:2009年48-45]
- The redox potential of the primary plastoquinone electron acceptor Q(A), E-m(Q(A)/Q(A)(-)), in an oxygen-evolging photosystem (PS) 11 complex from a thermophilic cyanobacterium Thermosynechococcus elongatus was determine...
- Synthesis and Evaluation of a Novel Class of G-Quadruplex-Stabilizing Small Molecules Based on the 1,3-Phenylene-Bis(piperazinyl benzimidazole) System
[作者:Jain, AK; Reddy, VV; Paul, A; Muniyappa, K; Bhattacharya, S,期刊:Biochemistry, 页码:10693-10704 , 文章类型: Article,,卷期:2009年48-45]
- Achieving stabilization of telomeric DNA in G-quadruplex conformation by Various organic compounds has been an important goal for the medicinal chemists seeking to develop new anticancer agents. Several compounds are kno...
- Helix Formation in Arrestin Accompanies Recognition of Photoactivated Rhodopsin
[作者:Feuerstein, SE; Pulvermuller, A; Hartmann, R; Granzin, J; Stoldt, M; Henklein, P; Ernst, OP; Heck, M; Willbold, D; Koenig, BW,期刊:Biochemistry, 页码:10733-10742 , 文章类型: Article,,卷期:2009年48-45]
- Binding of arrestin to photoactivated phosphorylated rhodopsin terminates the amplification of visual signals in photoreceptor cells. Currently, there is no crystal structure of a rhodopsin-arrestin complex available, al...
- Fragment-Based Discovery of BACE1 Inhibitors Using Functional Assays
[作者:Godemann, R; Madden, J; Kramer, J; Smith, M; Fritz, U; Hesterkamp, T; Barker, J; Hoppner, S; Hallett, D; Cesura, A; Ebneth, A; Kemp, J,期刊:Biochemistry, 页码:10743-10751 , 文章类型: Article,,卷期:2009年48-45]
- Novel nonpeptidic inhibitors of beta-secretase (BACE1) have been discovered by employing a fragment-based biochemical screening approach. A diverse library of 20000 low-molecular weight compounds were screened and yielde...
- Directed "in Situ" Inhibitor Elongation as a Strategy To Structurally Characterize the Covalent Glycosyl-Enzyme Intermediate of Human Pancreatic alpha-Amylase
[作者:Zhang, R; Li, CM; Williams, LK; Rempel, BP; Brayer, GD; Withers, SG,期刊:Biochemistry, 页码:10752-10764 , 文章类型: Article,,卷期:2009年48-45]
- While covalent catalytic intermediates of retaining alpha-transglycosylases have been Structurally characterized previously, no Such information for a hydrolytic alpha-amylase has been obtained. This Study presents a new...
- Kinetic Studies of HPr, HPr(H15D), HPr(H15E), and HPr(His similar to P) Phosphorylation by the Streptococcus salivarius HPr(Ser) Kinase/Phosphorylase
[作者:Casabon, I; Couture, M; Vaillancourt, K; Vadeboncoeur, C,期刊:Biochemistry, 页码:10765-10774 , 文章类型: Article,,卷期:2009年48-45]
- HPr is a central protein of the phosphoenolpyruvate:sugar phosphotransferase transport system (PTS). In streptococci, HPr can be phosphorylated at His(15) at the expense of PEP by enzyme I (El) of the PTS. producing HPr(...
- Characterization of Covalent Adducts of Nucleosides and DNA Formed by Reaction with Levuglandin
[作者:Carrier, EJ; Amarnath, V; Oates, JA; Boutaud, O,期刊:Biochemistry, 页码:10775-10781 , 文章类型: Article,,卷期:2009年48-45]
- Enhanced expression of cyclooxygenase-2 (COX-2) is associated with development of several cancers. The product of COX-2, prostaglandin H-2(PGH(2)), call undergo spontaneous rearrangement and nonenzymatic ring cleavage to...
- Interdomain Contacts in Flavocytochrome b(2), a Mutational Analysis
[作者:Le, KHD; Boussac, A; Frangioni, B; Leger, C; Lederer, F,期刊:Biochemistry, 页码:10803-10809 , 文章类型: Article,,卷期:2009年48-45]
- Each flavocytochrome b(2) (L-lactate cytochrome c oxidoreductase) subunit consists of an N-terminal cytochrome domain and a C-terminal flavodehydrogenase (FDH) domain. In the enzyme crystal structure, only two heme domai...
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