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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共14条记录   Challenges to human embryonic stem cell patents [作者：Plomer, A; Taymor, KS; Scott, CT,期刊：Cell Stem Cell, 页码：13-17 , 文章类型： Article，,卷期：2008年2-1] The patenting of human embryonic stem (hES) cells has produced one of the most unusual and fraught situations in the history of science, ethics, and law. This Commentary examines legal and moral challenges to three found... Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary [作者：Jin, ZG; Kirilly, D; Weng, CJ; Kawase, E; Song, XQ; Smith, S; Schwartz, J; Xie, T,期刊：Cell Stem Cell, 页码：39-49 , 文章类型： Article，,卷期：2008年2-1] Rapid progress has recently been made regarding how the niche controls stem cell function, but little is yet known about how stem cells in the same niche interact with one another. In this study, we show that differentia... A temporal switch from Notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis [作者：Brack, AS; Conboy, IM; Conboy, MJ; Shen, J; Rando, TA,期刊：Cell Stem Cell, 页码：50-59 , 文章类型： Article，,卷期：2008年2-1] The temporal switch from progenitor cell proliferation to differentiation is essential for effective adult tissue repair. We previously reported the critical role of Notch signaling in the proliferative expansion of myog... Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood [作者：Nostro, MC; Cheng, X; Keller, GM; Gadue, P,期刊：Cell Stem Cell, 页码：60-71 , 文章类型： Article，,卷期：2008年2-1] The embryonic stem cell differentiation system was used to define the roles of the Activin/Nodal, BMP, and canonical Wnt signaling pathways at three distinct developmental stages during hematopoietic ontogeny: induction ... BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway [作者：Lengerke, C; Schmitt, S; Bowman, TV; Jang, IH; Maouche-Chretien, L; McKinney-Freeman, S; Davidson, AJ; Hammerschmidt, M; Rentzsch, F; Green, JBA; Zon, LI; Daley, GQ,期刊：Cell Stem Cell, 页码：72-82 , 文章类型： Article，,卷期：2008年2-1] The formation of blood in the embryo is dependent on bone morphogenetic protein (BMP), but how BMP signaling intersects with other regulators of hematopoietic development is unclear. Using embryonic stem (ES) cells, we s... The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation [作者：Feng, CG; Weksberg, DC; Taylor, GA; Sher, A; Goodell, MA,期刊：Cell Stem Cell, 页码：83-89 , 文章类型： Article，,卷期：2008年2-1] Hematopoietic stem cells (HSCs) are self-renewing bone marrow cells that give rise to all blood lineages and retain a remarkable capacity to proliferate in response to insult. Although some controls on HSC activation are... Niche regulation of muscle satellite cell self-renewal and differentiation [作者：Kuang, S; Gillespie, MA; Rudnicki, MA,期刊：Cell Stem Cell, 页码：22-31 , 文章类型： Review，,卷期：2008年2-1] Muscle satellite cells have been shown to be a heterogeneous population of committed myogenic progenitors and noncommitted stem cells. This hierarchical composition of differentiating progenitors and self-renewable stem ... Stem cell regulation and host defense: The logic and the paradox [作者：Karlsson, G; Karlsson, S,期刊：Cell Stem Cell, 页码：1-2 , 文章类型： Editorial Material，,卷期：2008年2-1] As a response against serious infection, there is often a need to produce more leukocytes to defend the organism against the infectious agent. In this issue of Cell Stem Cell, Goodell and colleagues (Feng et al., 2008) f... Selfish stem cells compete with each other [作者：Yamashita, YM,期刊：Cell Stem Cell, 页码：3-4 , 文章类型： Editorial Material，,卷期：2008年2-1] Stem cell interactions with their niche have been well documented; however, the influences of stem cells on one another are rarely addressed. In this issue of Cell Stem Cell, Jin et al. (2008) demonstrate that stem cells... New insights into the control of stem cell pluripotency [作者：Gokhale, PJ; Andrews, PW,期刊：Cell Stem Cell, 页码：4-5 , 文章类型： Editorial Material，,卷期：2008年2-1] Nanog is a transcription factor that is expressed by mouse and human embryonic stem (ES) cells and by primordial germ cells. New research published recently in Nature (Chambers et al., 2007) points to an unexpected role ... Wnt not, waste not [作者：Wagers, AJ,期刊：Cell Stem Cell, 页码：6-7 , 文章类型： Editorial Material，,卷期：2008年2-1] The molecular signals that regulate the regenerative function of satellite cells in the skeletal muscle remain largely obscure. In this issue of Cell Stem Cell, Bracket al. (2008) report that direct molecular crosstalk b... Do cells let-7 determine stemness? [作者：Droge, P; Davey, CA,期刊：Cell Stem Cell, 页码：8-9 , 文章类型： Editorial Material，,卷期：2008年2-1] During oncogenic transformation, microRNA levels of the translation-regulatory factor let-7 correlate inversely with expression of the HMGA2 oncoprotein. In a recent issue of Cell, Yu et al. (2007) now provide evidence t... c-Myc is dispensable for direct reprogramming of mouse fibroblasts [作者：Wernig, M; Meissner, A; Cassady, JP; Jaenisch, R,期刊：Cell Stem Cell, 页码：10-12 , 文章类型： Editorial Material，,卷期：2008年2-1] Why myc? An unexpected ingredient in the stem cell cocktail [作者：Knoepfler, PS,期刊：Cell Stem Cell, 页码：18-21 , 文章类型： Review，,卷期：2008年2-1] Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cells has identified a surprising new embryonic stem cell regulator, the myc proto-oncogene. Here the possible mechanisms b...