Cell Stem Cell————————个性化文献订阅—

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
[作者：Brambrink, T; Foreman, R; Welstead, GG; Lengner, CJ; Wernig, M; Suh, H; Jaenisch, R,期刊：Cell Stem Cell, 页码：151-159 , 文章类型： Article，,卷期：2008年2-2]
Pluripotency can be induced in differentiated murine and human cells by retroviral transduction of Oct4, Sox2, Klf4, and c-Myc. We have devised a reprogramming strategy in which these four transcription factors are expre...

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3K4/K27 trimethylation
[作者：Fouse, SD; Shen, Y; Pellegrini, M; Cole, S; Meissner, A; Van Neste, L; Jaenisch, R; Fan, GP,期刊：Cell Stem Cell, 页码：160-169 , 文章类型： Article，,卷期：2008年2-2]
We report here genome-wide mapping of DNA methylation patterns at proximal promoter regions in mouse embryonic stem (mES) cells. Most methylated genes are differentiation associated and repressed in mES cells. By cont...

Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest
[作者：Takubo, K; Ohmura, M; Azuma, M; Nagamatsu, G; Yamada, W; Arai, F; Hirao, A; Suda, T,期刊：Cell Stem Cell, 页码：170-182 , 文章类型： Article，,卷期：2008年2-2]
Mammalian spermatogenesis is maintained by stem cell capacity within undifferentiated spermatogonial subpopulation. Here, using a combination of surface markers, we describe a purification method for undifferentiated spe...

Transparent adult zebrafish as a tool for in vivo transplantation analysis
[作者：White, RM; Sessa, A; Burke, C; Bowman, T; LeBlanc, J; Ceol, C; Bourque, C; Dovey, M; Goessling, W; Burns, CE; Zon, LI,期刊：Cell Stem Cell, 页码：183-189 , 文章类型： Article，,卷期：2008年2-2]
The zebrafish is a useful model for understanding normal and cancer stem cells, but analysis has been limited to embryogenesis due to the opacity of the adult fish. To address this, we have created a transparent adult ze...

Oct4 and its pseudogenes confuse stem cell research (vol 1, pg 364, 2007)
[作者：Liedtke, S; Enczmann, J; Waclawczyk, S; Wernet, P; Kogler, G,期刊：Cell Stem Cell, 页码：190-190 , 文章类型： Correction，,卷期：2008年2-2]

A critical time for stem cell research in Australia
[作者：Trounson, A; Harvey, RP,期刊：Cell Stem Cell, 页码：118-122 , 文章类型： Article，,卷期：2008年2-2]
Australia's strong historical foundation in stem cell science was boosted in 2002 by the formation of a virtual government-supported institute now called the Australian Stem Cell Centre. However, the inevitable "brain dr...

Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
[作者：Ren, GW; Zhang, LY; Zhao, X; Xu, GW; Zhang, YY; Roberts, AI; Zhao, RC; Shi, YF,期刊：Cell Stem Cell, 页码：141-150 , 文章类型： Article，,卷期：2008年2-2]
Mesenchymal stem cells (MSCs) can become potently immunosuppressive through unknown mechanisms. We found that the immunosuppressive function of MSCs is elicited by IFN gamma and the concomitant presence of any of three o...

Human ES cells and a blastocyst from one embryo: Exciting science but conflicting ethics?
[作者：Johnson, MH,期刊：Cell Stem Cell, 页码：103-104 , 文章类型： Editorial Material，,卷期：2008年2-2]
In this issue of Cell Stem Cell, Chung et al. (2008) remove a single blastomere to generate a human embryonic stem cell (hESC) line without prejudicing the development of the biopsied embryo. Their method stimulates new ...

A new role for an old friend: NFAT and stem cell quiescence
[作者：Oro, AE,期刊：Cell Stem Cell, 页码：104-106 , 文章类型： Editorial Material，,卷期：2008年2-2]
NFAT proteins are calcium-regulated transcription factors that play a critical role during the timing and activation of many vertebrate tissues. A recent paper in Cell (Horsley et al., 2008) demonstrates a role of the ca...

How do mesenchymal stromal cells suppress T cells?
[作者：Keating, A,期刊：Cell Stem Cell, 页码：106-108 , 文章类型： Editorial Material，,卷期：2008年2-2]
Accumulating information indicates that mesenchymal stem or stromal cells (MSCs) are immunomodulatory, but the data to explain the observations are frequently conflicting. In this issue of Cell Stem Cell, Ren et al. (200...

Germline stem cells: The first guards of heredity
[作者：Barroca, V; Fouchet, P,期刊：Cell Stem Cell, 页码：108-110 , 文章类型： Editorial Material，,卷期：2008年2-2]
The genes involved in the cellular response to DNA damage are crucial for ensuring DNA integrity during spermatogenesis. In this issue of Cell Stem Cell, Takubo et al. (2008) show that ATM, a key kinase of the DNA damage...

Foxa2: The rise and fall of dopamine neurons
[作者：Arenas, E,期刊：Cell Stem Cell, 页码：110-112 , 文章类型： Editorial Material，,卷期：2008年2-2]
Understanding the development and maintenance of dopamine neurons is essential to establish novel stem cell therapies and animal models of Parkinson's disease. A recent PLoS Biology report (Kittappa et al., 2007) reveals...

Human embryonic stem cell lines generated without embryo destruction
[作者：Chung, Y; Klimanskaya, I; Becker, S; Li, T; Maserati, M; Lu, SJ; Zdravkovic, T; Ilic, D; Genbacev, O; Fisher, S; Krtolica, A; Lanza, R,期刊：Cell Stem Cell, 页码：113-117 , 文章类型： Editorial Material，,卷期：2008年2-2]

Unraveling epigenetic regulation in embryonic stem cells
[作者：Bibikova, M; Laurent, LC; Ren, B; Loring, JF; Fan, JB,期刊：Cell Stem Cell, 页码：123-134 , 文章类型： Review，,卷期：2008年2-2]
Embryonic stem (ES) cells can replicate indefinitely while retaining the capacity to differentiate into functionally distinct cell types. ES cells proliferate and differentiate without detectable genetic changes, indicat...